Activation of a low specific activity form of DNA polymerase α by inositol-1,4-bisphosphate

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Early Signals in the Mitogenic Response

1986 • 1,498 citations

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

1988 • 1,027 citations

RECEPTORS AND PHOSPHOINOSITIDE-GENERATED SECOND MESSENGERS

1985 • 722 citations

The Metabolism of Phosphoinositide-Derived Messenger Molecules

1986 • 717 citations

Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerol.

1984 • 476 citations

Ras -Transformed Cells: Altered Levels of Phosphatidylinositol-4,5-Bisphosphate and Catabolites

1986 • 450 citations

Growth factor-stimulated protein phosphorylation in 3T3-L1 cells. Evidence for protein kinase C-dependent and -independent pathways.

1985 • 351 citations

An 81 kd protein complexed with middle T antigen and pp60c-src: A possible phosphatidylinositol kinase

1987 • 346 citations

The Molecular Basis of Communication within the Cell

1985 • 282 citations

Preparation and preliminary characterization of monoclonal antibodies against human DNA polymerase alpha.

1982 • 257 citations

Mitogens increase phosphorylation of phosphoinositides in thymocytes

1984 • 223 citations

Phospholipid Turnover in Hormone Action

1984 • 178 citations

Mutants of Chinese hamster ovary cells with altered membrane phospholipid composition. Replacement of phosphatidylinositol by phosphatidylglycerol in a myo-inositol auxotroph.

1980 • 174 citations

Mediators in cell growth and differentiation.

1984 • 166 citations

DNA primase from KB cells. Characterization of a primase activity tightly associated with immunoaffinity-purified DNA polymerase-alpha.

1984 • 160 citations

Growth and metabolism of inositol-starved Saccharomyces cerevisiae

1977 • 131 citations

Purification of a DNA polymerase-DNA primase complex from calf thymus glands.

1984 • 109 citations

Phorbol myristate acetate stimulates formation of phosphatidyl inositol 4-phosphate and phosphatidyl inositol 4,5-bisphosphate in human platelets

1984 • 103 citations

Stockpiling of DNA polymerases during oogenesis and embryogenesis in the frog, Xenopus laevis.

1985 • 65 citations

Phytohemagglutinin induces rapid degradation of phosphatidylinositol 4,5-bisphosphate and transient accumulation of phosphatidic acid and diacylglycerol in a human T lymphoblastoid cell line, CCRF-CEM.

1983 • 65 citations

Phosphatidylinositol turnover and transformation of cells by Abelson murine leukaemia virus.

1985 • 61 citations

A new possible regulatory system for protein phosphorylation in human peripheral lymphocytes. II. Possible relation to phosphatidylinositol turnover induced by mitogens.

1981 • 59 citations

Exposure of HeLa DNA polymerase alpha to protein kinase C affects its catalytic properties.

1987 • 58 citations

Stimulation of cell proliferation and polyphosphoinositide metabolism in Saccharomycescerevisiae GL7 by ergosterol

1985 • 54 citations

Phosphatidylinositol kinase activities in normal and Rous sarcoma virus-transformed cells.

1985 • 53 citations

Enzymological characterization of KB cell DNA polymerase-alpha. II. Specificity of the protein-nucleic acid interaction.

1979 • 53 citations

Phytohemagglutinin induces rapid degradation of phosphatidylinositol 4, 5-bisphosphate and transient accumulation of phosphatidic acid and diacylglycerol in a human T lymphoblastoid cell line, CCRF-CEM

1983 • 48 citations

Regulation of Cell Proliferation at the Onset of DNA Synthesis

1986 • 46 citations

Evidence from two transformed cell lines that the phosphorylations of peptide tyrosine and phosphatidylinositol are catalyzed by different proteins.

1985 • 39 citations

Evidence that a critical threshold of DNA polymerase‐alpha activity may be required for the initiation of DNA synthesis in mammalian cell heterokaryons

1982 • 33 citations

Involvement of the Ca2+/phospholipid-dependent protein kinase in the G1 transit of T51B rat liver epithelial cells

1985 • 27 citations

Stimulated Phosphatidylinositol Turnover A Brief Appraisal

1982 • 26 citations

A tumor promoter enhances the phosphorylation of polyphosphoinositides while decreasing phosphatidylinositol labelling in lymphocytes

1985 • 24 citations

Phosphatidylinositol-dependent activation of DNA polymerase alpha

1986 • 23 citations

Cell-cycle dependence and properties of the HeLa cell DNA polymerase system.

1985 • 22 citations

Detergent solubilization and hydrophobic chromatography of rat brain phosphatidylinositol kinase

1981 • 22 citations

Contemporary Metabolism

1982 • 19 citations

Lability of DNA polymerase alpha correlated with decreased DNA synthesis and increased age in human cells.

1987 • 14 citations

Monoclonal antibody that blocks phosphoinositide-dependent activation of mouse tumor DNA polymerase alpha

1986 • 13 citations

Repair of benzo[a]pyrene-initiated DNA damage in human cells requires activation of DNA polymerase alpha

1987 • 6 citations