Mutants of Chinese hamster ovary cells with altered membrane phospholipid composition. Replacement of phosphatidylinositol by phosphatidylglycerol in a myo-inositol auxotroph.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

PLAQUE FORMATION AND ISOLATION OF PURE LINES WITH POLIOMYELITIS VIRUSES

1954 • 3,832 citations

The Role of Polyamines in the Neutralization of Bacteriophage Deoxyribonucleic Acid

1960 • 2,598 citations

Inositol phospholipids and cell surface receptor function

1975 • 2,458 citations

AN ELECTRON-TRANSPORT SYSTEM ASSOCIATED WITH THE OUTER MEMBRANE OF LIVER MITOCHONDRIA

1967 • 2,311 citations

Measurement of Low Energy Beta-Emitters in Aqueous Solution by Liquid Scintillation Counting of Emulsions.

1965 • 1,475 citations

Form and function of phospholipids

1973 • 1,072 citations

Regulation of membrane enzymes by lipids

1978 • 906 citations

CLONAL GROWTH OF MAMMALIAN CELLS IN A CHEMICALLY DEFINED, SYNTHETIC MEDIUM

1965 • 833 citations

Techniques of Lipidology

1973 • 777 citations

A simplified spectrophotometric determination of ester groups in lipids

1959 • 595 citations

A simple method for the determination of serum cholesterol

1960 • 526 citations

Genetics of somatic mammalian cells, VII. Induction and isolation of nutritional mutants in Chinese hamster cells.

1968 • 460 citations

Enzymology, genetics, and regulation of membrane phospholipid synthesis in Escherichia coli

1978 • 321 citations

THE MINIMUM VITAMIN REQUIREMENTS OF THE L AND H<scp>E</scp>L<scp>A</scp> CELLS IN TISSUE CULTURE, THE PRODUCTION OF SPECIFIC VITAMIN DEFICIENCIES, AND THEIR CURE

1955 • 318 citations

Transfer of phospholipids between membrane

1974 • 314 citations

myo-INOSITOL AS AN ESSENTIAL GROWTH FACTOR FOR NORMAL AND MALIGNANT HUMAN CELLS IN TISSUE CULTURE

1957 • 268 citations

The Biosynthesis of Phosphatidylglycerol

1963 • 254 citations

Intracellular sites of lipid synthesis and the biogenesis of mitochondria

1972 • 218 citations

Phosphatidylglycerol in lung surfactant. III. Possible modifier of surfactant function

1976 • 195 citations

Membrane lipid biogenesis in Escherichia coli: identification of genetic loci for phosphatidylglycerophosphate synthetase and construction of mutants lacking phosphatidylglycerol.

1979 • 192 citations

Lipid Metabolism in Mammals

1977 • 184 citations

A two-dimensional thin-layer chromatographic procedure for the estimation of plasmalogens

1966 • 167 citations

Alteration of fatty acid composition of LM cells by lipid supplementation and temperature

1975 • 149 citations

Growth and metabolism of inositol-starved Saccharomyces cerevisiae

1977 • 131 citations

Subcellular and submitochondrial localization of the biosynthesis of cardiolipin and related phospholipids in rat liver

1972 • 128 citations

Use of a fluorescent probe to determine the viscosity of LM cell membranes with altered phospholipid compositions

1977 • 112 citations

Turnover of inositol and phosphorus containing lipids in Saccharomyces cerevisiae; extracellular accumulation of glycerophosphorylinositol derived from phosphatidylinositol

1972 • 110 citations

Isolation of Escherichia coli mutants defective in enzymes of membrane lipid synthesis.

1975 • 108 citations

The mechanism of cardiolipin biosynthesis in liver mitochondria

1972 • 105 citations

Changes in phospholipids of Saccharomyces cerevisiae associated with inositol-less death

1977 • 104 citations

Wildiers' Bios

1928 • 93 citations

Cyclitols and Phosphoinositides

1978 • 92 citations

Glycerophospholipid variation in choline and inositol auxotrophs of Neurospora crassa. Internal compensation among zwitterionic and anionic species.

1975 • 84 citations

Replica plating and in situ enzymatic assay of animal cell colonies established on filter paper.

1978 • 67 citations

THE SYNTHESIS OF INOSITOL IN THE IMMATURE RAT AND CHICK EMBRYO

1955 • 62 citations

Isolation and partial characterization of a cholesterol-requiring mutant of Chinese hamster ovary cells.

1977 • 61 citations

Isolation of lysosomal α-mannosidase mutants of Chinese hamster ovary cells

1979 • 57 citations

Animal cell mutants defective in sterol metabolism: A specific selection procedure and partial characterization of defects

1977 • 51 citations

Accumulation of neutral lipids in Saccharomyces carlsbergensis by myo-inositol deficiency and its mechanism. Reciprocal regulation of yeast acetyl-CoA carboxylase by fructose bisphosphate and citrate.

1976 • 49 citations

The effects of phosphatidylinositol on tyrosine hydroxylase. Stimulation and inactivation.

1979 • 44 citations

Mechanism of phosphatidylinostiol stimulation of lysosomal bis (monoacylglyceryl)phosphate synthesis.

1978 • 41 citations

On the solubility, stability and partial purification of CDPdiacyl-sn-glycerol-:lnosltol transferase from rat brain

1974 • 32 citations

THE FUNCTION OF CYTIDINE DIPHOSPHATE DIGLYCERIDE IN THE ENZYMATIC SYNTHESIS OF INOSITOL MONOPHOSPHATIDE¹

1959 • 17 citations

Action of FdUrd and dCyd on the incorporation of brdurd in Chinese hamster somatic cell DNA and the isolation of auxotrophic mutants

1977 • 10 citations