Where do triptans act in the treatment of migraine?
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Abstract
References (37)
The trigeminovascular system and migraine: Studies characterizing cerebrovascular and neuropeptide changes seen in humans and cats
1993 • 1,097 citations
Sensitization of meningeal sensory neurons and the origin of headaches
1996 • 667 citations
Migraine Headache Triggered Specifically by Sunlight: Report of 16 Cases
2013 • 646 citations
Triptans (Serotonin, 5-HT1B/1D Agonists) in Migraine: Detailed Results and Methods of A Meta-Analysis of 53 Trials
2002 • 576 citations
MECHANISM OF MIGRAINE HEADACHE AND ACTION OF ERGOTAMINE TARTRATE
1938 • 519 citations
Cortical spreading depression activates and upregulates MMP-9
2004 • 446 citations
Cortical spreading depression activates and upregulates MMP-9
2004 • 413 citations
Deconstructing migraine headache into peripheral and central sensitization
2001 • 354 citations
Disruption of communication between peripheral and central trigeminovascular neurons mediates the antimigraine action of 5HT 1B/1D receptor agonists
2004 • 247 citations
Inhibition by sumatriptan of central trigeminal neurones only after blood‐brain barrier disruption
1993 • 223 citations
Activation of 5‐HT1B/1D receptor in the periaqueductal gray inhibits nociception
2004 • 187 citations
Subcutaneous sumatriptan in the acute treatment of cluster headache: a dose comparison study
2009 • 185 citations
Preclinical Studies on the Anti-Migraine Drug, Sumatriptan
1991 • 171 citations
Comparison of the effects of sumatriptan and the NK1 antagonist CP-99,994 on plasma extravasation in dura mater and c-fos mRNA expression in trigeminal nucleus caudalis of rats
1995 • 169 citations
Sumatriptan: A Receptor-Targeted Treatment for Migraine
1993 • 168 citations
STIMULATION OF THE SUPERIOR SAGITTAL SINUS INCREASES METABOLIC ACTIVITY AND BLOOD FLOW IN CERTAIN REGIONS OF THE BRAINSTEM AND UPPER CERVICAL SPINAL CORD OF THE CAT
1991 • 162 citations
Peptidergic Nociceptors of Both Trigeminal and Dorsal Root Ganglia Express Serotonin 1D Receptors: Implications for the Selective Antimigraine Action of Triptans
2003 • 156 citations
Rizatriptan has central antinociceptive effects against durally evoked responses
1997 • 149 citations
Microiontophoretic application of serotonin (5HT)1B/1D agonists inhibits trigeminal cell firing in the cat
1997 • 129 citations
Detailed mapping of serotonin 5-HT1B and 5-HT1D receptor messenger RNA and ligand binding sites in guinea-pig brain and trigeminal ganglion: clues for function
1997 • 118 citations
The antimigraine 5‐HT1B/1D receptor agonists, sumatriptan, zolmitriptan and dihydroergotamine, attenuate pain‐related behaviour in a rat model of trigeminal neuropathic pain
2002 • 95 citations
Safety and efficacy of PNU-142633, a selective 5-HT1D agonist, in patients with acute migraine.
2001 • 90 citations
Differential effects of the 5HT1B/1D receptor agonist naratriptan on trigeminal versus spinal nociceptive responses
1998 • 89 citations
Safety and efficacy of PNU-142633, a selective 5-HT1D agonist, in patients with acute migraine
2001 • 82 citations
Changes in cerebral blood flow velocity after treatment with sumatriptan or placebo and implications for the pathophysiology of migraine
1996 • 76 citations
Comparison of More and Less Lipophilic Serotonin (5HT1B/1D) Agonists in a Model of Trigeminovascular Nociception in Cat
1998 • 53 citations
Lack of Antinociceptive Activity of Sumatriptan in Rodents
1990 • 52 citations
Inhibition of Inflammation-Induced Thermal Hypersensitivity by Sumatriptan through Activation of 5-HT1B/1D Receptors
2001 • 49 citations
Evidence for postjunctional serotonin (5‐HT1) receptors in the trigeminocervical complex
2001 • 48 citations
Expression of the 5-HT1B receptor by subtypes of rat trigeminal ganglion cells
1999 • 47 citations
Effects of sumatriptan on rat medullary dorsal horn neurons
2004 • 44 citations
Chronic Paroxysmal Hemicrania and Hemicrania Continua: Lack of Efficacy of Sumatriptan
1998 • 43 citations
Atypical facial pain: A double-blind placebo-controlled crossover pilot study of subcutaneous sumatriptan.
1997 • 36 citations
Migraine‐Associated Seizure: A Case of Reversible MRI Abnormalities and Persistent Nondominant Hemisphere Syndrome
2000 • 35 citations
Is myofascial pain of the temporal muscles relieved by oral sumatriptan? A cross-over pilot study
1995 • 32 citations
Cns Effects of Sumatriptan and Rizatriptan in Healthy Female Volunteers
2002 • 21 citations
Effect of sumatriptan in different models of pain in rats
2004 • 19 citations