Disruption of communication between peripheral and central trigeminovascular neurons mediates the antimigraine action of 5HT 1B/1D receptor agonists

Local effector functions of capsaicin-sensitive sensory nerve endings: Involvement of tachykinins, calcitonin gene-related peptide and other neuropeptides

1988 • 1,673 citations

Prevalence of Migraine Headache in the United States

1992 • 1,484 citations

Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model

2002 • 1,179 citations

An association between migraine and cutaneous allodynia

2000 • 953 citations

Sensitization of meningeal sensory neurons and the origin of headaches

1996 • 667 citations

Migraine Headache Triggered Specifically by Sunlight: Report of 16 Cases

2013 • 646 citations

Defeating migraine pain with triptans: A race against the development of cutaneous allodynia

2003 • 597 citations

Chemical Stimulation of the Intracranial Dura Induces Enhanced Responses to Facial Stimulation in Brain Stem Trigeminal Neurons

1998 • 576 citations

Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro

1992 • 490 citations

Neurogenically mediated leakage of plasma protein occurs from blood vessels in dura mater but not brain

1987 • 434 citations

The antimigraine drug, sumatriptan (GR43175), selectively blocks neurogenic plasma extravasation from blood vessels in dura mater

1990 • 422 citations

Migraine pain associated with middle cerebral artery dilatation: reversal by sumatriptan

1991 • 376 citations

Neurogenic inflammation in the pathophysiology and treatment of migraine.

1993 • 361 citations

Analgesic triptan action in an animal model of intracranial pain: A race against the development of central sensitization

2003 • 350 citations

A dominant role of acid pH in inflammatory excitation and sensitization of nociceptors in rat skin, in vitro

1995 • 285 citations

Mode of action of the anti-migraine drug sumatriptan

1991 • 249 citations

Neurovascular and molecular mechanisms in migraine headaches.

1993 • 226 citations

Differential Distribution of 5Ht_1D-and 5HT_1B-Immunoreactivity within the Human Trigemino-Cerebrovascular System: Implications for the Discovery of New Antimigraine Drugs

1997 • 225 citations

Peptidergic Nociceptors of Both Trigeminal and Dorsal Root Ganglia Express Serotonin 1D Receptors: Implications for the Selective Antimigraine Action of Triptans

2003 • 156 citations

5-HT1B and 5-HT1D receptors in the human trigeminal ganglion: co-localization with calcitonin gene-related peptide, substance P and nitric oxide synthase

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Inflammatory mediators potentiate pain induced by experimental tissue acidosis

1996 • 133 citations

The Site of Pain Origin During Migraine Attacks

1981 • 125 citations

Mechanical Response Properties of A and C Primary Afferent Neurons Innervating the Rat Intracranial Dura

2002 • 122 citations

Stimulation of the Calcitonin Gene-Related Peptide Enhancer by Mitogen-Activated Protein Kinases and Repression by an Antimigraine Drug in Trigeminal Ganglia Neurons

2003 • 117 citations

Calcitonin gene-related peptide is involved in the spinal processing of mechanosensory input from the rat's knee joint and in the generation and maintenance of hyperexcitability of dorsal horn neurons during development of acute inflammation

1996 • 107 citations

Colocalization of CGRP with 5‐HT_1B/1D receptors and substance P in trigeminal ganglion neurons in rats

2001 • 106 citations

Primary Afferent Neurons Innervating Guinea Pig Dura

1997 • 103 citations

Co-localization of 5-HT1B/1D/1F receptors and glutamate in trigeminal ganglia in rats

2001 • 96 citations

Endogenous monoamines inhibit glutamate transmission in the spinal trigeminal nucleus of the guinea‐pig.

1996 • 87 citations

Distinct sensitizing effects of the cAMP‐PKA second messenger cascade on rat dural mechanonociceptors

2002 • 85 citations

Differential Effects of 5-HT 1B/1D Receptor Agonists on Neurogenic Dural Plasma Extravasation and Vasodilation in Anaesthetized Rats

1997 • 73 citations

The Role of Spinal Neurokinin‐2 Receptors in the Processing of Nociceptive Information from the Joint and in the Generation and Maintenance of Inflammation‐evoked Hyperexcitability of Dorsal Horn Neurons in the Rat

1996 • 61 citations

Long-term clinical and electrophysiological results of local steroid injection in patients with carpal tunnel syndrome.

2000 • 49 citations

Serotonergic effects and extracellular brain levels of eletriptan, zolmitriptan and sumatriptan in rat brain

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Detection of loss of cerebral vascular tone by correlation of arterial and intracranial pressure signals

1995 • 40 citations

Endothelial expression of the 5-hydroxytryptamine1B antimigraine drug receptor in rat and human brain microvessels

1998 • 39 citations

Central and peripheral mechanisms of migraine.

2000 • 30 citations

Release of immunoreactive substance P in the brain stem upon stimulation of the cranial dura mater with low pH – inhibition by the serotonin (5‐HT₁) receptor agonist CP 93,129

1998 • 23 citations

Calcitonin gene-related peptide 8-37 inhibits the evoked discharge frequency of wide dynamic range neurons in dorsal horn of the spinal cord in rats

1999 • 23 citations

Spinal lamina I neurones that express neurokinin 1 receptors: II. Electrophysiological characteristics, responses to primary afferent stimulation and effects of a selective μ-opioid receptor agonist

2002 • 23 citations

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