Microiontophoretic application of serotonin (5HT)1B/1D agonists inhibits trigeminal cell firing in the cat

Nonparametric Statistics for the Behavioral Sciences

1958 • 36,277 citations

International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).

1994 • 2,935 citations

Vasoactive peptide release in the extracerebral circulation of humans during migraine headache

1990 • 1,514 citations

The trigeminovascular system and migraine: Studies characterizing cerebrovascular and neuropeptide changes seen in humans and cats

1993 • 1,097 citations

Headache and Other Head Pain

1949 • 815 citations

EXPERIMENTAL STUDIES ON HEADACHE

1940 • 751 citations

Alignment of receptor nomenclature with the human genome: classification of 5-HT1B and 5-HT1D receptor subtypes

1996 • 285 citations

Increase in plasma calcitonin gene-related peptide from the extracerebral circulation during nitroglycerin-induced cluster headache attack

1995 • 267 citations

Expression of c-Fos-like immunoreactivity in the caudal medulla and upper cervical spinal cord following stimulation of the superior sagittal sinus in the cat

1993 • 253 citations

Vasoactive Peptide Levels in The Plasma of Young Migraine Patients With and Without Aura Assessed Both Interictally and Ictally

1995 • 245 citations

The tentorial nerves and localization of intracranial pain in man

1960 • 226 citations

Inhibition by sumatriptan of central trigeminal neurones only after blood‐brain barrier disruption

1993 • 223 citations

Stimulation of the superior sagittal sinus in the cat causes release of vasoactive peptides

1990 • 223 citations

The distribution of trigeminovascular afferents in the nonhuman primate brain Macaca nemestrina: a c‐fos immunocytochemical study

1997 • 220 citations

Inhibition of trigeminal neurons by intravenous administration of the serotonin (5HT)1B/D receptor agonist zolmitriptan (311C90): are brain stem sites therapeutic target in migraine ?

1996 • 183 citations

Preclinical Studies on the Anti-Migraine Drug, Sumatriptan

1991 • 171 citations

A Double-blind Study of Subcutaneous Dihydroergotamine vs Subcutaneous Sumatriptan in the Treatment of Acute Migraine

1996 • 169 citations

Central activation of the trigeminovascular pathway in the cat is inhibited by dihydroergotamine

1996 • 169 citations

Peripheral and Central Trigeminovascular Activation in Cat is Blocked by the Serotonin (5HT)‐I D Receptor Agonist 311C90

1994 • 169 citations

Comparison of the effects of sumatriptan and the NK1 antagonist CP-99,994 on plasma extravasation in dura mater and c-fos mRNA expression in trigeminal nucleus caudalis of rats

1995 • 169 citations

Sumatriptan: A Receptor-Targeted Treatment for Migraine

1993 • 168 citations

STIMULATION OF THE SUPERIOR SAGITTAL SINUS INCREASES METABOLIC ACTIVITY AND BLOOD FLOW IN CERTAIN REGIONS OF THE BRAINSTEM AND UPPER CERVICAL SPINAL CORD OF THE CAT

1991 • 162 citations

Neural Processing of Craniovascular Pain: A Synthesis of the Central Structures Involved in Migraine

1991 • 158 citations

The Mode of Action of Sumatriptan is Vascular? A Debate

1994 • 155 citations

Localization of ³H‐Dihydroergotamine‐binding sites in the cat central nervous system: Relevance to migraine

1991 • 132 citations

Activation of trigeminal brain-stem nociceptive neurons by dural artery stimulation

1986 • 130 citations

Oral sumatriptan in acute migraine

1991 • 125 citations

Endothelin antagonist bosentan blocks neurogenic inflammation, but is not effective in aborting migraine attacks

1996 • 122 citations

Sumatriptan can inhibit trigeminal afferents by an exclusively neural mechanism

1996 • 117 citations

Direct Evidence for Central Sites of Action of Zolmitriptan (311C90)

1997 • 79 citations

Innervation of the posterior fossa dura of the cat

1985 • 78 citations

311C90, A new central and peripherally acting 5-HT _1D receptor agonist in the acute oral treatment of migraine

1996 • 71 citations

Comparative effects of stimulation of the trigeminal ganglion and the superior sagittal sinus on cerebral blood flow and evoked potentials in the cat

1988 • 70 citations

[3H]Sumatriptan binding sites in human brain: regional-dependent labelling of 5-HT1D and 5-HT1F receptors

1996 • 69 citations

Role of endothelin in mediating neurogenic plasma extravasation in rat dura mater

1996 • 66 citations

The spinal cord processing of input from the superior sagittal sinus: pathway and modulation by ergot alkaloids

1992 • 57 citations

Headaches During Intracranial Endovascular Procedures: A Possible Model of Vascular Headache

1993 • 49 citations

Alniditan in the Acute Treatment of Migraine Attacks

1996 • 43 citations

Autoradiographic mapping of [3H]sumatriptan binding in cat brain stem and spinal cord

1995 • 41 citations

[3H]dihydroergotamine as a high-affinity, slowly dissociating radioligand for 5-HT1B binding sites in rat brain membranes: evidence for guanine nucleotide regulation of agonist affinity states.

1987 • 41 citations

Focal Headache During Balloon Inflation in the Vertebral and Basilar Arteries

1993 • 40 citations

The in vivo pharmacological profile of a 5‐HT₁ receptor agonist, CP‐122, 288, a selective inhibitor of neurogenic inflammation

1995 • 37 citations

Cerebrovascular application of bradykinin excites central sensory neurons

1988 • 36 citations

Bench to bedside

1997 • 12 citations