Manganese Superoxide Dismutase Deficiency Exacerbates Cerebral Infarction After Focal Cerebral Ischemia/Reperfusion in Mice

Oxygen-Derived Free Radicals in Postischemic Tissue Injury

1985 • 5,488 citations

Oxidative Stress, Glutamate, and Neurodegenerative Disorders

1993 • 3,746 citations

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

1995 • 1,892 citations

A Semiautomated Method for Measuring Brain Infarct Volume

1990 • 1,610 citations

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

1980 • 1,609 citations

Biological effects of the superoxide radical

1986 • 1,446 citations

Role of Oxidants in Ischemic Brain Damage

1996 • 1,037 citations

Flow Cytometric Analysis of Respiratory Burst Activity in Phagocytes With Hydroethidine and 2′,7′-Dichlorofluorescin

1990 • 869 citations

Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine

1996 • 868 citations

Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate

1995 • 779 citations

Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia.

1994 • 571 citations

Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical

1998 • 489 citations

Mitochondrial Susceptibility to Oxidative Stress Exacerbates Cerebral Infarction That Follows Permanent Focal Cerebral Ischemia in Mutant Mice with Manganese Superoxide Dismutase Deficiency

1998 • 474 citations

Requirement for Superoxide in Excitotoxic Cell Death

1996 • 437 citations

Reduction of CuZn-Superoxide Dismutase Activity Exacerbates Neuronal Cell Injury and Edema Formation after Transient Focal Cerebral Ischemia

1997 • 436 citations

Overexpression of SOD1 in Transgenic Rats Protects Vulnerable Neurons Against Ischemic Damage After Global Cerebral Ischemia and Reperfusion

1998 • 335 citations

Manganese Superoxide Dismutase Mediates the Early Release of Mitochondrial Cytochrome C and Subsequent DNA Fragmentation after Permanent Focal Cerebral Ischemia in Mice

1999 • 315 citations

Transient Formation of Superoxide Radicals in Polyunsaturated Fatty Acid‐Induced Brain Swelling

1980 • 267 citations

Postischemic generation of superoxide anion by newborn pig brain

1988 • 175 citations

10-N Nonyl-Acridine Orange: A fluorescent probe which stains mitochondria independently of their energetic state

1989 • 156 citations

A simple fluorometric method for the determination of RNA and DNA in tissues.

1972 • 151 citations

Cellular distribution of superoxide dismutases in the rat CNS

2000 • 149 citations

Excitotoxicity is Required for Induction of Oxidative Stress and Apoptosis in Mouse Striatum by the Mitochondrial Toxin, 3-Nitropropionic Acid

2000 • 118 citations

Overexpression of copper/zinc superoxide dismutase does not prevent neonatal lethality in mutant mice that lack manganese superoxide dismutase

2000 • 103 citations

Chemiluminescence in hypoxic brain--the first report. Correlation between energy metabolism and free radical reaction.

1984 • 103 citations

Anti-death properties of TNF against metabolic poisoning: mitochondrial stabilization by MnSOD

1999 • 101 citations

Generation of superoxide anion by brain endothelial cell xanthine oxidase

1991 • 100 citations

Involvement of Oxidative Stress and Caspase-3 in Cortical Infarction after Photothrombotic Ischemia in Mice

2000 • 70 citations

Sr2+ activates cross-bridge phosphorylation and latch state in smooth muscle

1988 • 59 citations

Oxidative Stress and Neuronal DNA Fragmentation Mediate Age-Dependent Vulnerability to the Mitochondrial Toxin, 3-Nitropropionic Acid, in the Mouse Striatum

2001 • 59 citations

Early Decrease in DNA Repair Proteins, Ku70 and Ku86, and Subsequent DNA Fragmentation After Transient Focal Cerebral Ischemia in Mice

2001 • 51 citations

Reduced mitochondrial manganese-superoxide dismutase activity exacerbates glutamate toxicity in cultured mouse cortical neurons

1998 • 51 citations