Generation of superoxide anion by brain endothelial cell xanthine oxidase

A simplified method for the quantitative assay of small amounts of protein in biologic material

1973 • 1,802 citations

Characterization of ameboid microglia isolated from developing mammalian brain

1986 • 1,287 citations

The microestimation of succinate and the extinction coefficient of cytochrome c

1959 • 751 citations

Superoxide production in experimental brain injury

1986 • 420 citations

Permeation of the erythrocyte stroma by superoxide radical

1978 • 367 citations

The molecular basis of brain injury and brain edema

1990 • 355 citations

Significance of xanthine oxidase in capillary endothelial cells.

1986 • 333 citations

The Molecular Basis of Brain Injury and Brain Edema: The Role of Oxygen Free Radicals

1990 • 321 citations

Brain microvessel endothelial cells in tissue culture: A model for study of blood‐brain barrier permeability

1983 • 320 citations

Appearance of superoxide anion radical in cerebral extracellular space during increased prostaglandin synthesis in cats.

1985 • 296 citations

Identification of Hypoxanthine Transport and Xanthine Oxidase Activity in Brain Capillaries

1985 • 239 citations

Oxygen toxicity and reactive oxygen metabolites in mammals

1989 • 228 citations

Oxygen radicals mediate the cerebral arteriolar dilation from arachidonate and bradykinin in cats.

1984 • 215 citations

Xanthine oxidase-derived hydrogen peroxide contributes to ischemia reperfusion-induced edema in gerbil brains.

1988 • 208 citations

Molecular Basis of the Biological Function of Molybdenum

1974 • 205 citations

Role of xanthine oxidase and neutrophils in ischemia-reperfusion injury in rabbit lung

1990 • 182 citations

Hyperoxia increases H2O2 production by brain in vivo

1987 • 155 citations

Xanthine oxidase produces hydrogen peroxide which contributes to reperfusion injury of ischemic, isolated, perfused rat hearts.

1988 • 142 citations

Cerebral vasospasm: contractile activity of hemoglobin in isolated canine basilar arteries

1980 • 136 citations

Xanthine oxidase mediates elastase-induced injury to isolated lungs and endothelium

1987 • 87 citations

Oxygen Free Radicals in the Genesis of Traumatic and Peritumoral Brain Edema

1989 • 66 citations

Hyperoxia Damages Cultured Endothelial Cells Causing Increased Neutrophil Adherence

1983 • 66 citations

Superoxide production by human umbilical vein endothelial cells in an anoxia-reoxygenation model

1989 • 61 citations

Hyperoxia and self- or neutrophil-generated O2 metabolites inactivate xanthine oxidase

1988 • 49 citations

Regional distribution of α‐adrenoceptor subtypes in the female rabbit urethra

1986 • 42 citations

Effect of 4-hydroxypyrazolo (3,4-d) pyrimidine (allopurinol) on postirradiation cerebral blood flow: Implications of free radical involvement

1988 • 11 citations

Increased Uric Acid in the Developing Brain and Spinal Cord Following Cytomegalovirus Infection

1989 • 8 citations