Human plasma platelet-activating factor acetylhydrolase. Purification and properties.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*

1964 • 18,916 citations

The Role of Polyamines in the Neutralization of Bacteriophage Deoxyribonucleic Acid

1960 • 2,598 citations

Platelet-activating factor. Evidence for 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine as the active component (a new class of lipid chemical mediators).

1979 • 1,203 citations

Transphosphatidylation by Phospholipase D

1967 • 563 citations

Antihypertensive activity of an alkyl ether analog of phosphatidylcholine

1979 • 562 citations

Determination of Lecithin: Cholesterol Acyltransfer in Human Blood Plasma

1971 • 559 citations

Preparative and quantitative isolation of plasma lipoproteins: rapid, single discontinuous density gradient ultracentrifugation in a vertical rotor.

1980 • 549 citations

Physicochemical and Functional Identity of Rabbit Platelet-Activating Factor (PAF) Released in Vivo during IgE Anaphylaxis with PAF Released in Vitro from IgE Sensitized Basophils

1979 • 454 citations

Human endothelial cells in culture produce platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with thrombin.

1984 • 442 citations

A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid).

1981 • 440 citations

The release of platelet-activating factor from human endothelial cells in culture.

1983 • 436 citations

Human plasma platelet-activating factor acetylhydrolase. Association with lipoprotein particles and role in the degradation of platelet-activating factor.

1987 • 404 citations

Subfractionation of human high density lipoproteins by heparin-Sepharose affinity chromatography.

1980 • 349 citations

Glycerophospholipid synthesis: improved general method and new analogs containing photoactivable groups.

1977 • 315 citations

Lipoprotein-Polyanion-Metal Interactions1 1This investigation was supported in part by U. S. Public Health Service Research Grant HE-02965, and Training Grant TI HE-5273 and PO-AM 13430.

1973 • 272 citations

THE DISTRIBUTION AND METABOLISM OF ARACHIDONIC ACID IN RABBIT PLATELETS DURING AGGREGATION AND ITS MODIFICATION BY DRUGS

1977 • 264 citations

Platelet‐activating factor and macrophages. I. Evidence for the release from rat and mouse peritoneal macrophages and not from mastocytes

1979 • 244 citations

[6] Characterization of sialic acids

1978 • 243 citations

1-O-Alkyl-sn-glyceryl-3-phosphorylcholines: a novel class of neutrophil stimulants.

1981 • 237 citations

Preliminary studies of an acid-labile factor (ALF) in human sera that inactivates platelet-activating factor (PAF)

1980 • 207 citations

Association of Platelet-Activating Factor with Primary Acquired Cold Urticaria

1985 • 191 citations

Activities of enzymes that metabolize platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) in neutrophils and eosinophils from humans and the effect of a calcium ionophore

1982 • 174 citations

MULTIPLE SCLEROSIS

1975 • 174 citations

Inactivation of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine by a plasma acetylhydrolase: Higher activities in hypertensive rats

1983 • 169 citations

Biosynthesis of platelet activating factor in rabbit polymorphonuclear neutrophils.

1983 • 160 citations

9 Phospholipases

1983 • 159 citations

The molecular species distribution of platelet-activating factor synthesized by rabbit and human neutrophils.

1984 • 155 citations

Identification of phospholipid platelet-activating factor (1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine) in human amniotic fluid and urine

1983 • 140 citations

Contraction of guinea pig ileal smooth muscle by acetyl glyceryl ether phosphorylcholine

1981 • 134 citations

Regulation of platelet activating factor synthesis: Modulation of 1-alkyl-2-lyso-sn-glycero-3-phosphocholine:Acetyl-CoA acetyltransferase by phosphorylation and dephosphorylation in rat spleen microsomes

1984 • 104 citations

Presence of platelet-activating factor in blood from humans and experimental animals. Its absence in anephric individuals

1984 • 90 citations

Platelet-activating factor-mediated vasoconstriction and glycogenolysis in the perfused rat liver.

1986 • 86 citations

Substrate specificity and partial characterization of the PAF-acylhydrolase in human serum that rapidly inactivates platelet-activating factor.

1986 • 67 citations

AGGREGATION OF HUMAN PLATELETS BY PLATELET-ACTIVATING FACTOR

1975 • 66 citations

Fc receptor triggering induces expression of surface activation antigens and release of platelet-activating factor in large granular lymphocytes.

1986 • 65 citations

The presence of platelet-activating factor (PAF) in normal human mixed saliva.

1981 • 65 citations

Metabolism of platelet‐activating factor by blood platelets and plasma

1983 • 51 citations

Purification and characterization of a lysophospholipase from human amnionic membranes.

1984 • 50 citations

A sialic acid-specific O-acetylesterase in human erythrocytes: possible identity with esterase D, the genetic marker of retinoblastomas and Wilson disease.

1986 • 38 citations

Macrophage Activation by PAF Incorporated into Dipalmitoylphosphatidylcholine-Cholesterol Liposomes1

1985 • 26 citations

Human plasma carboxyl esterase-catalyzed triolein hydrolysis. Existence of promoting factor in serum.

1985 • 13 citations

Antigenic relatedness between human lecithin-cholesterol acyltransferase and phospholipases of the A2 family

1986 • 9 citations

228 Microvascular response to platelet activating factor (PAF-acether)

1983 • 7 citations