Altered Kinetics of Tap-1 Gene Expression in Macrophages Following Stimulation with both IFN-γ and LPS

Antigen Recognition by Class I-Restricted T Lymphocytes

1989 • 1,207 citations

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.

1991 • 1,132 citations

A Mechanism for the Specific Immunogenicity of Heat Shock Protein-Chaperoned Peptides

1995 • 838 citations

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4−8+ T cells

1992 • 726 citations

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters

1990 • 717 citations

A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway

1990 • 644 citations

Identification of human cancers deficient in antigen processing.

1993 • 625 citations

ANTIGEN PROCESSING AND PRESENTATION BY THE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX

1996 • 613 citations

Selective and ATP-Dependent Translocation of Peptides by the MHC-Encoded Transporter

1993 • 556 citations

Transport Protein Genes in the Murine MHC: Possible Implications for Antigen Processing

1990 • 438 citations

A new foreign policy: MHC class I molecules monitor the outside world

1996 • 422 citations

Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter

1991 • 413 citations

Absence of B7-dependent responses in CD28-deficient mice

1994 • 386 citations

TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective

1993 • 365 citations

MHC class l/β2-microglobulin complexes associate with TAP transporters before peptide binding

1994 • 356 citations

Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter

1991 • 329 citations

Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer

1992 • 322 citations

A role for the ubiquitin-dependent proteolytic pathway in MHC class l-restricted antigen presentation

1993 • 317 citations

Rapid cloning of HLA-A,B cDNA by using the polymerase chain reaction: frequency and nature of errors produced in amplification.

1990 • 306 citations

Interaction of MHC Class I Molecules with the Transporter Associated with Antigen Processing

1994 • 300 citations

Ham-2 corrects the class I antigen-processing defect in RMA-S cells

1992 • 289 citations

Regulation of c-myc transcription and mRNA abundance by serum growth factors and cell contact.

1986 • 254 citations

Polymorphism in a second ABC transporter gene located within the class II region of the human major histocompatibility complex.

1992 • 190 citations

Dependence of Peptide Binding by MHC Class I Molecules on Their Interaction with TAP

1995 • 189 citations

Human transporters associated with antigen processing possess a promiscuous peptide-binding site

1994 • 178 citations

Macrophages as accessory cells for class I MHC-restricted immune responses.

1991 • 148 citations

Cytotoxic T lymphocytes after oral immunization with attenuated vaccine strains of Salmonella typhi in humans.

1995 • 128 citations

Cytokines increase transporter in antigen processing-1 expression more rapidly than HLA class I expression in endothelial cells.

1992 • 115 citations

Major histocompatibility complex (MHC)-encoded HAM2 is necessary for antigenic peptide loading onto class I MHC molecules.

1992 • 111 citations

Kinetically coordinated induction of TAP1 and HLA class I by IFN-gamma: the rapid induction of TAP1 by IFN-gamma is mediated by Stat1 alpha.

1996 • 104 citations

Induction of c-fos and c-myc expression during B cell activation by IL-4 and immunoglobulin binding ligands.

1989 • 91 citations

Comparison of cell lines deficient in antigen presentation reveals a functional role for TAP-1 alone in antigen processing.

1994 • 89 citations

HIV-Infected Macrophages as Efficient Stimulator Cells for Detection of Cytotoxic T Cell Responses to HIV in Seronegative and Seropositive Vaccine Recipients

1994 • 12 citations

Target Cells of Cytotoxic T Lymphocytes Directed to the Individual Structural Proteins of Rabies Virus

1994 • 11 citations