Adjuvant therapy for cutaneous malignant melanoma
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Abstract
References (151)
Surg Clin North Am.
1986 • 8,793 citations
Cancer: Principles and Practice of Oncology.
1991 • 8,402 citations
Technical Details of Intraoperative Lymphatic Mapping for Early Stage Melanoma
1992 • 4,391 citations
A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma
1991 • 3,493 citations
Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684.
1996 • 2,073 citations
Cancer: Principles and Practice of Oncology
1994 • 1,825 citations
The Importance of Beta, the Type II Error and Sample Size in the Design and Interpretation of the Randomized Control Trial
1978 • 1,634 citations
Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor.
1994 • 1,108 citations
Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells
1980 • 1,094 citations
The Interferon System
1979 • 1,035 citations
Adjuvant Cyclophosphamide, Methotrexate, and Fluorouracil in Node-Positive Breast Cancer — The Results of 20 Years of Follow-up
1995 • 1,027 citations
The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas.
1993 • 986 citations
A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas.
1994 • 934 citations
Chemotherapy of Cancer
1958 • 874 citations
Randomized versus historical controls for clinical trials
1982 • 833 citations
Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes.
1994 • 771 citations
The Orderly Progression of Melanoma Nodal Metastases
1994 • 755 citations
High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma.
1992 • 730 citations
Melanocyte lineage-specific antigen gp100 is recognized by melanoma-derived tumor-infiltrating lymphocytes.
1994 • 584 citations
Improved survival in stage III melanoma patients with GM2 antibodies: a randomized trial of adjuvant vaccination with GM2 ganglioside.
1994 • 522 citations
Reporting on Methods in Clinical Trials
1982 • 503 citations
Immunological factors which influence response to immunotherapy in malignant melanoma.
1970 • 462 citations
Prolongation of Survival in Metastatic Melanoma After Active Specific Immunotherapy With a New Polyvalent Melanoma Vaccine
1992 • 410 citations
Demonstration of antibodies against human malignant melanoma by immunofluorescence.
1968 • 390 citations
A Multifactorial Analysis of Melanoma
1981 • 368 citations
Treatment of metastatic melanoma with an autologous tumor-cell vaccine: clinical and immunologic results in 64 patients.
1990 • 300 citations
A Randomized Trial of Adjuvant Chemotherapy and Immunotherapy in Cutaneous Melanoma
1982 • 282 citations
Multivariate Analysis
1983 • 280 citations
Lymphatic Drainage of Skin to a Sentinel Lymph Node in a Feline Model
1991 • 280 citations
Detection of Submicroscopic Lymph Node Metastases with Polymerase Chain Reaction in Patients with Malignant Melanoma
1994 • 280 citations
Drug-Induced Restoration of Cutaneous Delayed Hypersensitivity in Anergic Patients with Cancer
1973 • 264 citations
Sample Size Nomograms For Interpreting Negative Clinical Studies
1983 • 261 citations
Fraction size in external beam radiation therapy in the treatment of melanoma
1991 • 258 citations
An Additional Basic Science for Clinical Medicine: II. The Limitations of Randomized Trials
1983 • 257 citations
Randomized, surgical adjuvant clinical trial of recombinant interferon alfa-2a in selected patients with malignant melanoma.
1995 • 253 citations
Active specific immunotherapy for melanoma: phase I trial of allogeneic lysates and a novel adjuvant.
1988 • 239 citations
BCG and Cancer
1974 • 238 citations
Vaccines containing purified GM2 ganglioside elicit GM2 antibodies in melanoma patients.
1987 • 224 citations
Surface antigens of melanoma and melanocytes. Specificity of induction of Ia antigens by human gamma-interferon.
1984 • 224 citations
ŒSTROGEN RECEPTORS IN HUMAN MALIGNANT MELANOMA
1976 • 220 citations
Treatment of patients with melanoma of the extremity using hyperthermic isolated limb perfusion with melphalan, tumor necrosis factor, and interferon gamma: results of a tumor necrosis factor dose-escalation study.
1996 • 212 citations
Quality-of-life-adjusted survival analysis of interferon alfa-2b adjuvant treatment of high-risk resected cutaneous melanoma: an Eastern Cooperative Oncology Group study.
1996 • 206 citations
Management of Early-Stage Melanoma by Intraoperative Lymphatic Mapping and Selective Lymphadenectomy: An Alternative to Routine Elective Lymphadenectomy or “Watch and Wait”
1992 • 201 citations
Immunotherapy of Human Cancer
1983 • 174 citations
Ganglioside GM2 as a human tumor antigen (OFA-I-1).
1983 • 174 citations
Melanoma cells and normal melanocytes share antigens recognized by HLA-A2-restricted cytotoxic T cell clones from melanoma patients.
1993 • 173 citations
Prognostic Factors in Patients Undergoing Lymphadenectomy of Malignant Melanoma
1977 • 163 citations
Factors Prognostic for Survival in Patients with Malignant Melanoma Spread to the Regional Lymph Nodes
1982 • 163 citations
Spontaneous regression of human melanoma.Clinical and experimental studies
1960 • 156 citations
Polymerase Chain Reaction Detection of Circulating Melanocytes as a Prognostic Marker in Patients With Melanoma
1995 • 150 citations
Malignant melanoma patients with positive nodes and relatively good prognoses: Microstaging retains prognostic significance in clinical stage I melanoma patients with metastases to regional nodes
1981 • 142 citations
Clinical Trials and Statistical Verdicts: Probable Grounds for Appeal
1983 • 139 citations
Regional hyperthermic perfusion with melphalan after surgery for recurrent malignant melanoma of the extremities. Swedish Melanoma Study Group.
1991 • 135 citations
Adjuvant radiation therapy for regional nodal metastases from malignant melanoma. A randomized, prospective study
1978 • 133 citations
Characterization of the Inhibitory Effects of Retinoids on the In Vitro Growth of Two Malignant Murine Melanomas2
1978 • 132 citations
The prognosis of primary and metastasising melanoma. An evaluation of the TNM classification in 2,495 patients
1992 • 128 citations
DTIC and combination therapy for melanoma: III. DTIC (NSC 45388) surgical adjuvant study COG PROTOCOL 7040
1981 • 126 citations
In transit metastases of malignant melanoma treated by high dose rTNFα in combination with interferon‐γ and melphalan in isolation perfusion
1992 • 124 citations
Corynebacterium parvum as an immunotherapeutic anticancer agent.
1974 • 124 citations
Regional Radiotherapy as Adjuvant Treatment for Head and Neck Malignant Melanoma: Preliminary Results
1990 • 123 citations
A phase III randomized, doúble-blind, multiinstitutional trial of vaccinia melanoma oncolysate-active specific immunotherapy for patients with stage II melanoma
1995 • 121 citations
Inhibition of the Growth and Development of a Transplantable Murine Melanoma by Vitamin A
1975 • 116 citations
Randomized Trial of Adjuvant Human Interferon Gamma Versus Observation in High-Risk Cutaneous Melanoma: a Southwest Oncology Group Study
1995 • 111 citations
Immunotherapy of Human Cancer
1982 • 110 citations
Levamisole Inhibits and Cures a Solid Malignant Tumour and its Pulmonary Metastases in Mice
1972 • 110 citations
Administration of recombinant interferon gamma to cancer patients enhances monocyte secretion of hydrogen peroxide.
1985 • 110 citations
A membrane antigen common to human cancer and fetal brain tissues.
1976 • 106 citations
Active Specific Immunotherapy of Melanoma with Allogeneic Cell Lysates Rationale, Results, and Possible Mechanisms of Actiona
1993 • 97 citations
Regional non-nodal metastases of cutaneous melanoma.
1986 • 94 citations
Relationship between immune response to melanoma vaccine immunization and clinical outcome in stage II malignant melanoma
1992 • 89 citations
Angiogenesis and the skin: A primer
1996 • 86 citations
Spontaneous regression of melanoma. Report of a case
1953 • 82 citations
Improved survival in patients with poor-prognosis malignant melanoma treated with adjuvant levamisole: a phase III study by the National Cancer Institute of Canada Clinical Trials Group.
1991 • 81 citations
Recombinant gamma-interferon induces changes in expression and shedding of antigens associated with normal human melanocytes, nevus cells, and primary and metastatic melanoma cells.
1985 • 81 citations
Adjuvant Immunotherapy or Chemotherapy for Malignant Melanoma: Preliminary Report of the National Cancer Institute Randomized Clinical Trial
1981 • 79 citations
Pooled Analysis of the Efficacy of Bacille Calmette‐Guerin (BCG) Immunotherapy in Malignant Melanoma
1993 • 78 citations
A randomized trial of levamisole versus placebo as adjuvant therapy in malignant melanoma.
1991 • 76 citations
Identification of tumour rejection antigens recognized by T lymphocytes.
1992 • 72 citations
Understanding and evaluating clinical trials
1996 • 71 citations
A randomized prospective clinical trial of adjuvant C. parvum immunotherapy in 260 patients with clinically localized melanoma (Stage I):Prognostic factors analysis and preliminary results of immunotherayp
1982 • 70 citations
Controlled trial of active immunotherapy in management of stage IIB malignant melanoma.
1977 • 67 citations
Clinical and histologic involvement of regional lymph nodes in malignant melanoma. Adjuvant vindesine improves survival
1994 • 67 citations
Studies of interferons in the therapy of melanoma.
1991 • 67 citations
Favorable prognostic factors in recurrent and metastatic melanoma
1996 • 67 citations
An Additional Basic Science for Clinical Medicine: III. The Challenges of Comparison and Measurement
1983 • 65 citations
Active Immunotherapy of Human Melanoma Exploiting the Immunopotentiating Effects of Cyclophosphamide
1988 • 63 citations
Cutaneous Malignant Melanoma: Prognostic Guidelines for Physicians and Patients
1982 • 63 citations
Improved survival of patients with melanoma with an antibody response to immunization to a polyvalent melanoma vaccine
1995 • 62 citations
Corynebacterium parvum versus bacille Calmette-Guérin adjuvant immunotherapy of stage II malignant melanoma.
1991 • 60 citations
Positron Emission Tomography and Ultrasonography
1995 • 58 citations
Evaluation of efficacy of adjuvant rIFN-alfa-2a in melanoma patients with regional nodal metastases (abstract)
1995 • 57 citations
The role of elective lymph node dissection in the management of patients with thick cutaneous melanoma
1990 • 57 citations
Hyperthermic perfusion with chemotherapy for melanoma of the extremities
1989 • 55 citations
Corynebacterium parvum versus BCG adjuvant immunotherapy in human malignant melanoma
1983 • 54 citations
Long-term adjuvant immunotherapy in stage I high risk malignant melanoma, comparing two BCG preparations versus non-treatment in a randomised multicentre study (EORTC protocol 18781)
1993 • 53 citations
Prognosis of Thick Cutaneous Melanoma of the Trunk and Extremity
1990 • 52 citations
A randomized phase I/II study of continuous versus intermittent intravenous interferon gamma in patients with metastatic melanoma.
1987 • 52 citations
The identification and mapping of melanoma regional nodal metastases: minimally invasive surgery for the diagnosis of nodal metastases.
1995 • 49 citations
Randomized trial of adjuvant therapy for "high risk" primary malignant melanoma.
1978 • 47 citations
DTIC and combination therapy for melanoma
1981 • 47 citations
Randomized trial of vitamin A versus observation as adjuvant therapy in high-risk primary malignant melanoma: a Southwest Oncology Group study.
1994 • 47 citations
Late Recurrence (Beyond Ten Years) of Cutaneous Malignant Melanoma
1984 • 46 citations
ADJUVANT BCG IMMUNOTHERAPY FOR MALIGNANT MELANOMA?
1983 • 45 citations
Historic milestones in curative chemotherapy.
1979 • 44 citations
Illusion and reality: practical pitfalls in interpreting clinical trials.
1984 • 41 citations
Phase II study of recombinant interferon-gamma in patients with disseminated malignant melanoma.
1987 • 40 citations
Randomized Trial of High Dose Chemotherapy With Autologous Bone Marrow Support as Adjuvant Therapy for High-Risk, Multi-Node Positive Malignant Melanoma
1993 • 40 citations
The Role of Selective Lymphadenectomy in the Management of Patients with Malignant Melanoma
1995 • 39 citations
The female superiority in survival in clinical stage. II. Cutaneous malignant melanoma
1982 • 38 citations
Natural history of malignant melanoma as related to therapy.
1976 • 38 citations
Multivariate analysis. Some guidelines for physicians
1983 • 34 citations
Adjuvant immunotherapy of malignant melanoma
1979 • 34 citations
The significance of conversion of skin reactivity to efficacy of bacillus Calmette-Gu�rin (BCG) vaccinations given immediately after radical surgery in stage II melanoma patients
1989 • 34 citations
Double blind randomized prospective trial of levamisole/placebo in stage I cutaneous malignant melanoma.
1987 • 34 citations
A Prospective, Randomized Controlled Trial of Megestrol Acetate Among High-Risk Patients with Resected Malignant Melanoma
1989 • 33 citations
New approaches in metastatic melanoma: biological and molecular targeted therapies
2007 • 32 citations
Randomized controlled trial of transfer factor in stage II malignant melanoma
1983 • 30 citations
A randomized trial of adjuvant chemotherapy and immunotherapy in stage I and stage II cutaneous melanoma. An interim report
1985 • 30 citations
Randomized trial of adjuvant therapy for “high risk” primary malignant melanoma
1979 • 29 citations
Randomized study of Corynebacterium parvum adjuvant therapy following surgery for (Stage II) malignant melanoma
1986 • 29 citations
Improved Graphs for Calculating Sample Sizes When Comparing Two Independent Binomial Distributions
1979 • 27 citations
Specific active immunotherapy does not prolong survival in surgically treated patients with stage IIB malignant melanoma and may promote early recurrence
1978 • 27 citations
A randomized, double-blind, placebo-controlled trial of transfer factor as adjuvant therapy for malignant melanoma
1988 • 26 citations
Lack of benefit of adjunctive chemotherapy in stage I malignant melanoma: a Southwest Oncology Group Study.
1987 • 26 citations
Adjuvant therapy of cutaneous malignant melanoma: A critical review
1985 • 26 citations
Predictors of Late deaths among patients with clinical stage I melanoma who have not had bony or visceral metastases within the first 5 years after diagnosis
1983 • 26 citations
Adjuvant treatment of malignant melanoma with DTIC + estracyt or BCG
1987 • 25 citations
A quality‐adjusted survival meta‐analysis of adjuvant chemotherapy for premenopausal breast cancer
1995 • 25 citations
Multimodal Primary Cancer Treatment (Adjuvant Chemotherapy): Current Results and Future Prospects
1979 • 24 citations
A review of transfer factor immunotherapy in cancer
1974 • 23 citations
Clinical Activity of a Polyvalent Melanoma Antigen Vaccine
1995 • 23 citations
The use of tumour necrosis factor (TNF) in isolated perfusion: results and side effects. The NCI results.
1994 • 20 citations
Lack of effect of cyclophosphamide on the immunogenicity of a melanoma antigen vaccine.
1991 • 19 citations
Chemoimmunotherapy (DTIC and Corynebacterium parvum) as adjuvant treatment in malignant melanoma.
1979 • 18 citations
Comparison of the Potentiation of Specific Tumor Immunity in Mice by Corynebacterium parvum or BCG 2
1976 • 18 citations
Tumour regression and survival of patients with disseminated malignant melanoma treated with chemotherapy and specific active immunotherapy
1977 • 17 citations
Patients and physicians as obstacles to a randomized trial.
1981 • 16 citations
Regional lymph node dissection for malignant melanoma of the extremities.
1981 • 16 citations
Surgical Adjuvant Therapy for Malignant Melanoma
1981 • 16 citations
Role of beta1 integrins in melanocyte cell spreading and migration on ECM and their possible role in the process of tumor invasion and metastasis
1994 • 14 citations
BCG immunotherapy in stage I melanoma patients
1986 • 14 citations
Randomized controlled trial of adjuvant chemoimmunotherapy with DTIC and BCG after complete excision of primary melanoma with a poor prognosis or melanoma metastases.
1983 • 13 citations
Adjuvant Chemotherapy for Cancer
1977 • 12 citations
Phase III adjuvant studies in operable malignant melanoma (review).
1987 • 11 citations
Adjuvant Treatment in Stage I and II Malignant Melanoma: A Randomized Trial between Chemoimmunotherapy and Immunotherapy
1991 • 10 citations
Regional lymph node dissection for malignant melanoma of the extremities
1981 • 8 citations
Adjuvant chemotherapy in cancer.
1977 • 4 citations
Cancer Vaccines, Disappointing In the Past, Show Promise
1996 • 3 citations
Adjuvant Cancer Therapy: Rationale for Its Use
1981 • 2 citations
Endocrinology of melanoma
1996 • 2 citations
Deleted Work
1955 • 0 citations
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