Evidence for higher rates of nucleotide substitution in rodents than in man.

A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences

1980 • 28,067 citations

The structure and evolution of the human β-globin gene family

1980 • 1,398 citations

Biochemical Evolution

1977 • 1,283 citations

Human fetal gγ- and Aγ-globin genes: Complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes

1980 • 947 citations

Immunological Time Scale for Hominid Evolution

1967 • 726 citations

Sequence of the human insulin gene

1980 • 553 citations

Rate of Fixation of Nucleotide Substitutions in Evolution

1969 • 506 citations

The nucleotide sequence of the human β-globin gene

1980 • 502 citations

The structure and evolution of the two nonallelic rat preproinsulin genes

1979 • 500 citations

Structure and Evolution of the Growth Hormone Gene Family

1983 • 402 citations

Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments

1980 • 402 citations

The evolution and sequence comparison of two recently diverged mouse chromosomal β-globin genes

1979 • 337 citations

The complete sequence of a chromosomal mouse α-globin gene reveals elements conserved throughout vertebrate evolution

1979 • 317 citations

Nucleotide sequence divergence and functional constraint in mRNA evolution.

1980 • 249 citations

Cloning and complete nucleotide sequence of mouse immunoglobulin γ1 chain gene

1979 • 230 citations

Structure of a genomic clone encoding biologically active human relaxin

1983 • 227 citations

The gene encoding the common alpha subunit of the four human glycoprotein hormones.

1981 • 225 citations

Complete amino acid sequence of mouse pro-opiomelanocortin derived from the nucleotide sequence of pro-opiomelanocortin cDNA.

1983 • 207 citations

Nucleotide sequence of the rat skeletal muscle actin gene

1982 • 207 citations

The primary structure of the human ε-globin gene

1980 • 195 citations

Phylogenetic origins and adaptive evolution of avian and mammalian haemoglobin genes

1982 • 194 citations

Nucleotide sequence of cloned cDNAs encoding human preproparathyroid hormone.

1981 • 183 citations

Structural organization of human genomic DNA encoding the pro-opiomelanocortin peptide.

1980 • 181 citations

Molecular cloning and characterization of cDNA sequences coding for rat relaxin

1981 • 164 citations

alpha Subunit of rat pituitary glycoprotein hormones. Primary structure of the precursor determined from the nucleotide sequence of cloned cDNAs.

1982 • 160 citations

The nucleotide sequence of a human immnnoglobulin C_γlgene

1982 • 158 citations

Complete nucleotide sequence of the human δ-globin gene

1980 • 146 citations

A new troponin T and cDNA clones for 13 different muscle proteins, found by shotgun sequencing

1983 • 139 citations

Cloning and complete nucleotide sequence of human 5'-alpha-globin gene.

1980 • 136 citations

Complete nucleotide sequence of the human corticotropin-β-lipotropin precursor gene

1983 • 124 citations

Gene encoding parathyroid hormone. Nucleotide sequence of the rat gene and deduced amino acid sequence of rat preproparathyroid hormone.

1984 • 120 citations

Isolation and characterization of the mouse corticotropin‐β‐lipotropin precursor gene and a related pseudogene

1983 • 105 citations

Structure and evolution of goat γ-, βC- and βA-globin genes: Three developmentally regulated genes contain inserted elements

1981 • 104 citations

Isolation and Characterization of the Bovine Corticotropin/β-Lipotropin Precursor Gene

2005 • 100 citations

Isolation and characterization of cDNA clones for human skeletal muscle α actin

1983 • 93 citations

Gene conversion of two functional goat alpha-globin genes preserves only minimal flanking sequences.

1982 • 93 citations

Estimating the total number of nucleotide substitutions since the common ancestor of a pair of homologous genes: Comparison of several methods and three beta hemoglobin messenger RNA's

1980 • 75 citations

Porcine Relaxin: Molecular Cloning and cDNA Structure

1982 • 73 citations

Two mouse early embryonic beta-globin gene sequences. Evolution of the nonadult beta-globins.

1984 • 70 citations

Cloning and nucleotide sequence analysis of the dog insulin gene. Coded amino acid sequence of canine preproinsulin predicts an additional C-peptide fragment.

1983 • 58 citations

Nucleotide sequence of a cDNA for the common alpha subunit of the bovine pituitary glycoprotein hormones. Conservation of nucleotides in the 3'-untranslated region of bovine and human pre-alpha subunit mRNAs.

1983 • 56 citations

Comparison of the beta-like globin gene families of rabbits and humans indicates that the gene cluster 5'-epsilon-gamma-delta-beta-3' predates the mammalian radiation.

1984 • 55 citations

Rabbit immunoglobulin kappa genes: structure of a germline b4 allotype J-C locus and evidence for several b4-related sequences in the rabbit genome.

1983 • 53 citations

The sequence of a mouse embryonic beta-globin gene. Evolution of the gene and its signal region.

1982 • 52 citations

A maximum likelihood estimate of the sex ratio of mutation rates in Haemophilia A

1983 • 38 citations

Molecular cloning of rabbit γ heavy chain mRNA

1982 • 11 citations