Ca2+-dependent Control of the Permeability Properties of the Mitochondrial Outer Membrane and Voltage-dependent Anion-selective Channel (VDAC)

The versatility and universality of calcium signalling

2000 • 5,407 citations

The Pathophysiology of Mitochondrial Cell Death

2004 • 3,258 citations

Close Contacts with the Endoplasmic Reticulum as Determinants of Mitochondrial Ca ²⁺ Responses

1998 • 2,130 citations

The mitochondrial calcium uniporter is a highly selective ion channel

2004 • 1,348 citations

Microdomains with High Ca ²⁺ Close to IP ₃ -Sensitive Channels that Are Sensed by Neighboring Mitochondria

1993 • 1,167 citations

Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins

1998 • 1,094 citations

The internal structure of mitochondria

2000 • 810 citations

Properties of the Permeability Transition Pore in Mitochondria Devoid of Cyclophilin D

2005 • 787 citations

Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death

1999 • 610 citations

Quasi-synaptic calcium signal transmission between endoplasmic reticulum and mitochondria

1999 • 530 citations

VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release

2001 • 507 citations

Bcl-xL Prevents Cell Death following Growth Factor Withdrawal by Facilitating Mitochondrial ATP/ADP Exchange

1999 • 496 citations

VDAC: The channel at the interface between mitochondria and the cytosol

2003 • 470 citations

A candidate for the permeability pathway of the outer mitochondrial membrane

1979 • 459 citations

Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria

2002 • 432 citations

Evolutionary conservation of biogenesis of β-barrel membrane proteins

2003 • 425 citations

Mitochondrial ADP/ATP Carrier Can Be Reversibly Converted into a Large Channel by Ca²⁺

1996 • 421 citations

Voltage-dependent anion channel (VDAC) as mitochondrial governator—Thinking outside the box

2005 • 421 citations

In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death

2004 • 389 citations

Calcium binding and translocation by the voltage-dependent anion channel: a possible regulatory mechanism in mitochondrial function

2001 • 350 citations

Mitochondrial Depolarization Accompanies Cytochrome cRelease During Apoptosis in PC6 Cells

1999 • 347 citations

Electrophysiological Study of a Novel Large Pore Formed by Bax and the Voltage-dependent Anion Channel That Is Permeable to Cytochrome c

2000 • 335 citations

Perinuclear, perigranular and sub-plasmalemmal mitochondria have distinct functions in the regulation of cellular calcium transport

2001 • 312 citations

pH difference across the outer mitochondrial membrane measured with a green fluorescent protein mutant

2004 • 284 citations

Role of mitochondrial membrane permeabilization in apoptosis and cancer

2004 • 271 citations

Selectivity Changes in Site-Directed Mutants of the VDAC Ion Channel: Structural Implications

1990 • 269 citations

ATP Flux Is Controlled by a Voltage-gated Channel from the Mitochondrial Outer Membrane

1996 • 235 citations

Calcium binding and translocation by the voltage-dependent anion channel: a possible regulatory mechanism in mitochondrial function

2001 • 232 citations

Oligomeric states of the voltage-dependent anion channel and cytochrome c release from mitochondria

2005 • 201 citations

NADH regulates the gating of VDAC, the mitochondrial outer membrane channel.

1994 • 200 citations

Life's smile, death's grin: vital functions of apoptosis-executing proteins

2004 • 187 citations

The mitochondrial permeability transition pore may comprise VDAC molecules

1993 • 172 citations

The mitochondrial permeability transition pore may comprise VDAC molecules

1993 • 166 citations

Old players in a new role: mitochondria-associated membranes, VDAC, and ryanodine receptors as contributors to calcium signal propagation from endoplasmic reticulum to the mitochondria

2002 • 161 citations

Ca ²⁺ marks: Miniature calcium signals in single mitochondria driven by ryanodine receptors

2002 • 148 citations

The cationically selective state of the mitochondrial outer membrane pore: a study with intact mitochondria and reconstituted mitochondrial porin

1990 • 147 citations

Retarded diffusion of ADP in cardiomyocytes: possible role of mitochondrial outer membrane and creatine kinase in cellular regulation of oxidative phosphorylation

1993 • 134 citations

Modulation of Neisseria Porin (PorB) by Cytosolic ATP/GTP of Target Cells: Parallels between Pathogen Accommodation and Mitochondrial Endosymbiosis

1996 • 133 citations

Porin pores of mitochondrial outer membranes from high and low eukaryotic cells: biochemical and biophysical characterization

1987 • 127 citations

Molecular genetics of the VDAC ion channel: Structural model and sequence analysis

1987 • 121 citations

Beginnings of a signal-transduction pathway for bioenergetic control of cell survival

2004 • 114 citations

The Voltage-dependent Anion Channel Is the Target for a New Class of Inhibitors of the Mitochondrial Permeability Transition Pore

2003 • 106 citations

A simple and rapid method for the purification of the mitochondrial porin from mammalian tissues

1987 • 98 citations

Sorting of calcium signals at the junctions of endoplasmic reticulum and mitochondria

2001 • 96 citations

Prolonged Activation of Mitochondrial Conductances During Synaptic Transmission

1999 • 93 citations

Plasticity of Mitochondrial Calcium Signaling

2003 • 84 citations

tcBid promotes Ca2+ signal propagation to the mitochondria: control of Ca2+ permeation through the outer mitochondrial membrane

2002 • 81 citations

Bax increases the pore size of rat brain mitochondrial voltage-dependent anion channel in the presence of tBid

2004 • 79 citations

A soluble mitochondrial protein increases the voltage dependence of the mitochondrial channel, VDAC

1992 • 59 citations

Nucleotide-binding Sites in the Voltage-dependent Anion Channel

2005 • 56 citations

Circular dichroism studies of the mitochondrial channel, VDAC, from Neurospora crassa

1996 • 53 citations

New Insights into the Mechanism of Permeation through Large Channels

2005 • 49 citations

Positive cooperativity without domains or subunits in a monomeric membrane channel

2000 • 43 citations

Cytoplasmic Cellular Structures Control Permeability of Outer Mitochondrial-Membrane for ADP and Oxidative-Phosphorylation in Rat-Liver Cells

1995 • 38 citations

Evidence for a novel voltage‐activated channel in the outer mitochondrial membrane

1987 • 30 citations

Ionic permeability of the mitochondrial outer membrane

1992 • 28 citations

Transport properties and inhibitor sensitivity of isolated and reconstituted porin differ from those of intact mitochondria

1993 • 20 citations

The voltage-dependent anion channel as a biological transistor: theoretical considerations

2003 • 9 citations