Electrophysiological Study of a Novel Large Pore Formed by Bax and the Voltage-dependent Anion Channel That Is Permeable to Cytochrome c

Mitochondria and Apoptosis

1998 • 8,909 citations

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

1997 • 7,177 citations

Caspases: Enemies Within

1998 • 6,923 citations

The Bcl-2 Protein Family: Arbiters of Cell Survival

1998 • 5,359 citations

The mitochondrial permeability transition

1995 • 2,412 citations

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

1999 • 2,157 citations

Bax directly induces release of cytochrome c from isolated mitochondria

1998 • 1,514 citations

Bax and Adenine Nucleotide Translocator Cooperate in the Mitochondrial Control of Apoptosis

1998 • 1,183 citations

Inhibition of Bax Channel-Forming Activity by Bcl-2

1997 • 1,023 citations

Bax interacts with the permeability transition pore to induce permeability transition and cytochromecrelease in isolated mitochondria

1998 • 932 citations

Bcl-xL forms an ion channel in synthetic lipid membranes

1997 • 817 citations

Bax-induced Caspase Activation and Apoptosis via Cytochromec Release from Mitochondria Is Inhibitable by Bcl-xL

1999 • 717 citations

Bcl‐2 family: Life‐or‐death switch

2000 • 665 citations

Bax-induced Cytochrome C Release from Mitochondria Is Independent of the Permeability Transition Pore but Highly Dependent on Mg2+ Ions

1998 • 645 citations

Channel formation by antiapoptotic protein Bcl-2

1997 • 604 citations

Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane

1994 • 561 citations

Structure-Function Analysis of Bcl-2 Protein

1995 • 419 citations

Voltage gating in the mitochondrial channel, VDAC

1989 • 296 citations

Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel.

1993 • 239 citations

The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4

1998 • 237 citations

The protein bcl-2 alpha does not require membrane attachment, but two conserved domains to suppress apoptosis.

1994 • 186 citations

The mitochondrial permeability transition pore may comprise VDAC molecules

1993 • 166 citations

Investigation of bax‐induced release of cytochrome c from yeast mitochondria

1999 • 131 citations

Functional Dissection of the Human Bcl2 Protein: Sequence Requirements for Inhibition of Apoptosis

1996 • 126 citations

VDAC/porin is present in sarcoplasmic reticulum from skeletal muscle

1996 • 121 citations

Evidence for α-Helical Conformation of an Essential N-terminal Region in the Human Bcl2 Protein

1996 • 50 citations

Channel Active Mammalian Porin, Purified from Crude Membrane Fractions of Human B Lymphocytes or Bovine Skeletal Muscle, Reversibly Binds the Stilbene-Disulfonate Group of the Chloride Channel Blocker DIDS

1994 • 49 citations

Novel Aspects of the Electrophysiology of Mitochondrial Porin

1998 • 39 citations

Binding of a synthetic targeting peptide to a mitochondrial channel protein

1992 • 15 citations

ATP-Sensitive Anion Channel from Rat Brain Synaptosomal Membranes Incorporated into Planar Lipid Bilayers

1997 • 5 citations