Positive cooperativity without domains or subunits in a monomeric membrane channel

Formation of Bimolecular Membranes from Lipid Monolayers and a Study of Their Electrical Properties

1972 • 1,746 citations

Principles of enzyme kinetics

1976 • 468 citations

Allosteric Receptors after 30 Years

1998 • 430 citations

Is cooperative oxygen binding by hemoglobin really understood?

1999 • 315 citations

Polymer inaccessible volume changes during opening and closing of a voltage-dependent ionic channel

1986 • 289 citations

Principles of Enzyme Kinetics

1976 • 282 citations

Selectivity Changes in Site-Directed Mutants of the VDAC Ion Channel: Structural Implications

1990 • 269 citations

Protonation dynamics of the alpha-toxin ion channel from spectral analysis of pH-dependent current fluctuations

1995 • 194 citations

Amino-terminal Myristoylation Induces Cooperative Calcium Binding to Recoverin

1995 • 192 citations

Current noise reveals protonation kinetics and number of ionizable sites in an open protein ion channel

1993 • 192 citations

Structure of the outer mitochondrial membrane: ordered arrays of porelike subunits in outer-membrane fractions from neurospora crassa mitochondria

1982 • 162 citations

Cooperative Interactions of Hemoglobin

1975 • 160 citations

ATP Transport Through a Single Mitochondrial Channel, VDAC, Studied by Current Fluctuation Analysis

1998 • 148 citations

Evidence for cooperative interactions in potassium channel gating

1992 • 144 citations

Allosteric activation and tuning of ligand efficacy in cyclic-nucleotide-gated channels

1997 • 105 citations

The Topology of VDAC as Probed by Biotin Modification

1998 • 104 citations

Zero-current potentials in a large membrane channel: a simple theory accounts for complex behavior

1993 • 72 citations

Surface topography and molecular stoichiometry of the mitochondrial channel, VDAC, in crystalline arrays*1

1991 • 65 citations

Ionization-linked Changes in Protein Conformation. I. Theory

1961 • 64 citations

pH‐Dependent Interactions of Cd²⁺ and a Carboxylate Blocker with the Rat ClC‐1 Chloride Channel and Its R304E Mutant in the Sf‐9 Insect Cell Line

1997 • 49 citations

Diameter of the mitochondrial outer membrane channel: Evidence from electron microscopy of frozen‐hydrated membrane crystals

1989 • 44 citations

Determination of the number of polypeptide subunits in a functional VDAC channel fromSaccharomyces cerevisiae

1992 • 44 citations

[27] Isolation and properties of the porin of the outer mitochondrial membrane from Neurospora crassa

1983 • 30 citations

Effects of intracellular pH on ATP‐sensitive K+ channels in mouse pancreatic beta‐cells.

1994 • 30 citations

Two-sided action of protons on an inward rectifier K + channel (IRK1)

1997 • 28 citations

Thermodynamic and kinetic cooperativity in ligand binding to multiple sites on a protein: Ca2+ activation of an ATP-driven Ca pump.

1985 • 22 citations

Contributions of individual molecular species to the hill coefficient for ligand binding by an oligomeric protein

1997 • 13 citations