Renal proximal tubular cells in suspension or in primary culture as in vitro models to study nephrotoxicity

Chapter 4 Preparation of Isolated Rat Liver Cells

1976 • 5,335 citations

"Panning" for lymphocytes: a method for cell selection.

1978 • 1,319 citations

Polarized monolayers formed by epithelial cells on a permeable and translucent support

1978 • 869 citations

Casarett and Doull's toxicology: The basic science of poisons

1987 • 798 citations

The chemistry, biochemistry and biology of cadmium

1980 • 646 citations

The origin and characteristics of a pig kidney cell strain, LLC-PK1

1976 • 604 citations

Studies on the Renal Glomerular Basement Membrane

1967 • 506 citations

Effect of cyclosporine administration on renal hemodynamics in conscious rats

1985 • 416 citations

Criteria of Viability of Isolated Liver Cells

1975 • 411 citations

RENAL TUBULAR TRANSPORT: ACCUMULATION OF P-AMINOHIPPURATE BY RABBIT KIDNEY SLICES

1950 • 407 citations

D-valine as a selective agent for normal human and rodent epithelial cells in culture

1975 • 392 citations

Functions of Glutathione in Liver and Kidney

1978 • 352 citations

Isolation of a pure suspension of rat proximal tubules

1981 • 349 citations

Characterization of an Established Line of Canine Kidney Cells (MDCK).

1966 • 330 citations

Apical membrane aminopeptidase appears at site of cell-cell contact in cultured kidney epithelial cells.

1980 • 329 citations

Tissue culture of human kidney epithelial cells of proximal tubule origin

1984 • 317 citations

Retention of differentiated properties in an established dog kidney epithelial cell line (MDCK).

1979 • 315 citations

Epithelioid and fibroblastic rat kidney cell clones: Epidermal growth factor (EGF) receptors and the effect of mouse sarcoma virus transformation

1978 • 296 citations

Characterization of primary rabbit kidney cultures that express proximal tubule functions in a hormonally defined medium.

1982 • 293 citations

Cytoprotective effects of glycine and glutathione against hypoxic injury to renal tubules.

1987 • 274 citations

Na+/HCO3-co-transport in basolateral membrane vesicles isolated from rabbit renal cortex.

1986 • 237 citations

New Complexon for Titration of Calcium in Presence of Magnesium

1957 • 199 citations

Metabolic compartmentation

1983 • 199 citations

Establishment and characterization of a cell line from the american opossum (Didelphys virginiana)

1978 • 196 citations

The Madin Darby canine kidney (MDCK) epithelial cell monolayer as a model cellular transport barrier.

1989 • 185 citations

Effect of diethyldithiocarbamate on cis-diamminedichloroplatinum(II)-induced cytotoxicity, DNA cross-linking, and gamma-glutamyl transpeptidase inhibition.

1986 • 182 citations

ATP and the Regulation of Renal Cell Function

1986 • 175 citations

Transport properties of toad kidney epithelia in culture

1981 • 164 citations

Use of isolated kidney cells for study of drug metabolism

1979 • 162 citations

Selective protection against cis-diamminedichloroplatinum(II)-induced toxicity in kidney, gut, and bone marrow by diethyldithiocarbamate.

1986 • 158 citations

The MDCK epithelial cell line expresses a cell surface antigen of the kidney distal tubule.

1982 • 156 citations

Komplexone VI. Neue einfache Titriermethoden zur Bestimmung der Wasserhärte

1946 • 155 citations

Glutathione uptake and protection against oxidative injury in isolated kidney cells

1988 • 152 citations

Bioactivation of Nephrotoxic Haloalkenes by Glutathione Conjugation: Formation of Toxic and Mutagenic Intermediates by Cysteine Conjugate β-Lyase

1989 • 151 citations

Biology of Amphibian Tumors

1969 • 151 citations

Mixed Disulfides: Biological Functions and Increase in Oxidative Stress

1985 • 149 citations

Cytotoxicity of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine in isolated rat kidney cells.

1986 • 147 citations

Cisplatin nephrotoxicity: insights into mechanism

1987 • 147 citations

MORPHOLOGICAL SIMILARITIES BETWEEN THE DOG KIDNEY CELL LINE MDCK AND THE MAMMALIAN CORTICAL COLLECTING TUBULE*

1981 • 146 citations

Ultrastructural and biochemical analyses of isolated basement membranes from kidney glomeruli and tubules and brain and retinal microvessels

1978 • 141 citations

Metabolism of glutathione and a glutathione conjugate by isolated kidney cells.

1979 • 140 citations

Epithelial Cells in Tissue Culture

1988 • 134 citations

Glucose transport in the kidney

1976 • 122 citations

Renal heterogeneity and target cell toxicity

1986 • 119 citations

Mass Culture of Amphibian Cells: Methods and Observations Concerning Stability of Cell Type

1969 • 116 citations

Use of Thin Kidney Slices and Isolated Renal Tubules for Direct Study of Cellular Transport Kinetics

1948 • 115 citations

Isolation, Culture and Characterization of Human Renal Tubular Cells

1985 • 115 citations

Chemically Induced Nephrotoxicity: Role of Metabolic Activation

1984 • 110 citations

Na+-dependent hexose transport in vesicles from cultured renal epithelial cell line

1982 • 109 citations

Coupled transport of p-aminohippurate by rat kidney basolateral membrane vesicles

1988 • 108 citations

Identification of proximal tubular transport functions in the established kidney cell line, OK

1987 • 106 citations

Studies on the Mechanism of Nephrotoxicity and Nephrocarcinogenicity of Halogenated Alkenes

1988 • 104 citations

Transepithelial transport in cell culture:d-Glucose transport by a pig kidney cell line (LLC-PK1)

1981 • 104 citations

Defined human renal tubular epithelia in culture: growth, characterization, and hormonal response

1985 • 104 citations

Transport and metabolism of glucose by renal proximal tubular cells in primary culture

1984 • 103 citations

The role of glutathione conjugate metabolism and cysteine conjugate beta-lyase in the mechanism of S-cysteine conjugate toxicity in LLC-PK1 cells.

1986 • 103 citations

Drug metabolism — from molecules to man

1988 • 102 citations

Oxygen deprivation-induced injury to isolated rabbit kidney tubules.

1985 • 102 citations

Improved renal cortical tubule suspension: spectrophotometric study of O2 delivery

1980 • 99 citations

Effect of the organic acid transport inhibitor probenecid on renal cortical uptake and proximal tubular toxicity of hexachloro-1,3-butadiene and its conjugates*1

1985 • 98 citations

Tissue Culture of Epithelial Cells

1985 • 97 citations

The use of metrizamide as a gradient medium for isopycnic separation of rat liver cells

1974 • 88 citations

Cell separation methods

1977 • 88 citations

Improved separation method for rat proximal and distal renal tubules

1987 • 85 citations

Properties of Wilms' tumor line (TuWi) and pig kidney line (LLC-PK1) typical of normal kidney tubular epithelium

1979 • 84 citations

Isolation, growth, and characterization of a gluconeogenic strain of renal cells

1987 • 82 citations

Biochemical mechanisms of cephaloridine nephrotoxicity: Time and concentration dependence of peroxidative injury

1986 • 81 citations

Differential response to hormones of defined distal nephron epithelia in culture

1983 • 79 citations

Metabolic inhibitors: effects on metabolism and transport in the proximal tubule

1982 • 79 citations

Studies of kidney cells in culture

1986 • 77 citations

Nephrotoxicity of S-(2-chloro-1,1,2-trifluoroethyl)glutathione and S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine, the glutathione and cysteine conjugates of chlorotrifluoroethene.

1985 • 77 citations

Homogeneous cell populations from rabbit kidney cortex. Proximal, distal tubule, and renin-active cell isolated by free-flow electrophoresis.

1977 • 75 citations

Studies on final differentiation of rat renal proximal tubular cells in culture

1986 • 75 citations

A Rapid Method for separating Glomeruli from Rabbit Kidney

1958 • 74 citations

Renal clearance and isolated kidney perfusion techniques

1986 • 72 citations

Formation and metabolism of a glutathione-S-conjugate in isolated rat liver and kidney cells

1978 • 70 citations

Isolation of two distinct populations of cells from fat kidney cortex and their use in the study of chemical-induced toxicity

1989 • 70 citations

Uptake of nephrotoxic S-conjugates by isolated rat renal proximal tubular cells.

1989 • 69 citations

Serum dependent growth of primary cultured differentiated fetal rat hepatocytes in arginine‐deficient medium

1973 • 68 citations

Active ion transport in the renal proximal tubule. I. Transport and metabolic studies.

1984 • 67 citations

Characteristics of glutathione biosynthesis by freshly isolated rat kidney cells.

1980 • 66 citations

The mechanism of pentachlorobutadienyl-glutathione nephrotoxicity studied with isolated rat renal epithelial cells

1986 • 66 citations

Effect of aminoglycoside antibiotics on cellular functions of kidney epithelial cell line (LLC-PK1): a model system for aminoglycoside nephrotoxicity.

1984 • 66 citations

Electrophysiology and ultrastructure of cultured human proximal tubule cells

1988 • 66 citations

EFFECT OF ACETATE ON THE RENAL EXCRETION OF P-AMINOHIPPURATE IN THE DOG

1950 • 65 citations

Cisplatin nephrotoxicity: In vitro studies with precision-cut rabbit renal cortical slices

1987 • 64 citations

The regulation of intracellular pH in monkey kidney epithelial cells (BSC-1). Roles of Na+/H+ antiport, Na+-HCO3(-)-(NaCO3-) symport, and Cl-/HCO3- exchange.

1986 • 64 citations

Occluding junctions in a renal cell line (LLC-PK1) with characteristics of proximal tubular cells

1986 • 63 citations

Differential patterns of injury to the proximal tubule of renal cortical slices following in vitro exposure to mercuric chloride, potassium dichromate, or hypoxic conditions*1, *2

1987 • 63 citations

Effects of cis-diamminedichloroplatinum(II) on rabbit kidney in vivo and on rabbit renal proximal tubule cells in culture.

1988 • 63 citations

Overview of Epithelial Polarity

1989 • 62 citations

Nephron segment and calcium as determinants of anoxic cell death in renal cultures

1986 • 59 citations

Renal transport processes and glutathione conjugate-mediated nephrotoxicity.

1987 • 59 citations

Proximal tubule characteristics of cultured human renal cortex epithelium.

1989 • 58 citations

Assessment of unscheduled DNA synthesis in a cultured line of renal epithelial cells exposed to cysteine S-conjugates of haloalkenes and haloalkanes

1989 • 58 citations

Expression of a differentiated transport function in apical membrane vesicles isolated from an established kidney epithelial cell line. Sodium electrochemical potential-mediated active sugar transport.

1982 • 56 citations

A mechanism of S-(1,2,3,4,4-pentachloro-1,3-butadienyl)-l-cysteine toxicity to rabbit renal proximal tubules

1987 • 55 citations

Renal cysteine conjugate β-lyase-mediated toxicity studied with primary cultures of human proximal tubular cells

1990 • 54 citations

Toxicity of the cysteine-S-conjugates and mercapturic acids of four structurally related difluoroethylenes in isolated proximal tubular cells from rat kidney

1989 • 54 citations

Modulation of cyclic AMP-dependent protein kinase by vasopressin and calcitonin in cultured porcine renal LLC-PK1 cells

1980 • 54 citations

Use of monoclonal antibodies to isolate cortical collecting tubule cells: AVP induces PGE release

1983 • 54 citations

Preparation of positional renal slices for study of cell-specific toxicity

1987 • 53 citations

Continuous free-flow electrophoresis as an analytical and preparative method in biology

1978 • 53 citations

Renal cell culture

1988 • 53 citations

Rat kidney epithelial cell culture for metal toxicity studies

1985 • 53 citations

N-acetyl S-(1,2-dichlorovinyl)-l-cysteine produces a similar toxicity to S-(1,2-dichlorovinyl)-l-cysteine in rabbit renal slices: differential transport and metabolism

1989 • 51 citations

Preclinical detection of nephrotoxicity: description of the tests and appraisal of their health significance

1989 • 50 citations

Differentiated function in cultured epithelia derived from thick ascending limbs

1982 • 50 citations

Intracellular distribution and depletion of glutathione in rabbit renal proximal tubules

1988 • 50 citations

Isolated proximal tubular cells from rat kidney as an in vitro model for studies on nephrotoxicity

1989 • 49 citations

Toxicity of S-pentachlorobutadienyl-l-cysteine studied with isolated rat renal cortical mitochondria

1987 • 49 citations

A Comparison of Drug-Metabolizing Capability in Isolated Viable Rat Hepatocytes and Renal Tubule Fragments

1978 • 49 citations

Nephrotoxicity of mercapturic acids of three structurally related 2,2-difluoroethylenes in the rat

1988 • 49 citations

Assessment of unscheduled and replicative DNA synthesis in rat kidney cells exposed in vitro or in vivo to unleaded gasoline*1

1987 • 47 citations

In vitro growth and differentiation of human kidney tubular cells on a basement membrane substrate

1987 • 47 citations

Effects of gentamicin on sphingomyelinase activity in cultured human renal proximal tubular cells.

1987 • 47 citations

Nephrotoxicity and hepatotoxicity of 1,1-dichloro-2,2-difluoroethylene in the rat

1987 • 46 citations

Rat kidney proximal tubule cells in defined medium: The roles of cholera toxin, extracellular calcium and serum in cell growth and expression of γ-glutamyltransferase

1989 • 46 citations

Rat kidney function related to tissue glutathione levels

1986 • 46 citations

Organic anion transport across the contraluminal membrane—Dependence on sodium

1989 • 45 citations

Transport and activation of S-(1,2-dichlorovinyl)-l-cysteine and N-acetyl-S-(1,2-dichlorovinyl)-l-cysteine in rat kidney proximal tubules

1989 • 45 citations

Effect of age and dietary restriction on protein synthesis by isolated kidney cells

1985 • 44 citations

Analytical cell fractionation of isolated rabbit renal proximal tubules

1981 • 43 citations

Protein kinase C activation has dissimilar effects on sodium-coupled uptakes in renal proximal tubular cells in primary culture

1989 • 43 citations

The transport of S-cysteine conjugates in LLC-PK1 cells and its role in toxicity.

1987 • 43 citations

Differential effects of nephrotoxic agents on renal organic ion transport and metabolism.

1973 • 43 citations

Aminoglycoside-induced alterations in apical membranes of kidney epithelial cell line (LLC-PK1)

1988 • 43 citations

Glutathione protects against exogenous oxidant injury to rabbit renal proximal tubules

1988 • 42 citations

The use of renal cortical slices from the Fischer 344 rat as an in vitro model to evaluate nephrotoxicity*1

1988 • 41 citations

Growth factor regulation of the renal cortical tubular cells by epidermal growth factor, insulin-like growth factor-I, acidic and basic fibroblast growth factor, and transforming growth factor-β in serum free culture

1989 • 41 citations

Characterization of primar cell cultures derived from rat renal proximal tubules

1989 • 41 citations

Role of endogenous sulfur-containing nucleophiles in an in vitro model of cis-diamminedichloroplatinum(II)-induced nephrotoxicity

1990 • 40 citations

Nephrotoxicity assessment by measuring cellular ATP content

1989 • 40 citations

Cellular toxicity of bromobenzene and bromobenzene metabolites to rabbit proximal tubules: the role and mechanism of 2-bromohydroquinone.

1986 • 39 citations

Phosphate uptake by proximal cells isolated from rabbit kidney: role of dexamethasone

1985 • 39 citations

Immunodissection: use of monoclonal antibodies to isolate specific types of renal cells

1985 • 39 citations

Basal-lateral transport and transcellular flux of methyl α-d-glucoside across LLC-PK1 renal epithelial cells

1986 • 39 citations

Transport of N-acetyl-S-pentachloro-1,3-butadienylcysteine by rat renal cortex

1986 • 38 citations

Effect of gentamicin on the lysosomal system of cultured human proximal tubular cells

1989 • 38 citations

Vasopressin stimulates growth of renal epithelial cells in culture

1983 • 37 citations

Primary cultures of rabbit renal proximal tubule cells: I. Growth and biochemical characteristics

1989 • 37 citations

[16] Preparation and characteristics of isolated kidney cells

1981 • 37 citations

Isolation of rat kidney cortical tubules enriched in proximal and distal segments

1979 • 37 citations

Turnover of Cellular Glutathione in Isolated Rat‐Kidney Cells

1981 • 37 citations

Characteristics of the Na+-H+ antiporter in the intact renal proximal tubular cell

1986 • 37 citations

Transport of tetraethylammonium by a kidney epithelial cell line (LLC-PK1)

1988 • 37 citations

Primary culture of proximal tubular cells from normal rat kidney as an in vitro model to study mechanisms of nephrotoxicity

1990 • 36 citations

Differentiated lines of cells from rabbit renal medullary thick ascending limbs grown on amnion

1985 • 36 citations

Renal cortical cells in primary monolayer culture

1979 • 35 citations

Lipid alterations in LLC-PK1 cells exposed to mercuric chloride

1986 • 35 citations

An established cell line from mouse kidney medullary thick ascending limb. I. Cell culture techniques, morphology, and antigenic expression

1986 • 35 citations

Transport–dependent cell injury in the S3 segment of the proximal tubule

1986 • 35 citations

Brush-border TEA transport in intact proximal tubules and isolated membrane vesicles

1989 • 35 citations

Nephrotoxicity in the experimental and clinical situation

1987 • 35 citations

Mechanisms mediating cephaloridine inhibition of renal gluconeogenesis

1987 • 35 citations

Retention of differentiated characteristics by cultures of defined rabbit kidney epithelia

1987 • 34 citations

Biochemical mechanisms of nephrotoxicity.

1985 • 34 citations

Multiple effects of presumed glutathione depletors on rabbit proximal tubules

1986 • 33 citations

Enhancement of endotoxin-induced isolated renal tubular cell injury by toxic shock syndrome toxin 1.

1986 • 33 citations

A new method for the isolation of ultrastructurally preserved glomeruli

1976 • 33 citations

Stimulation of calcium transport of sarcoplasmic reticulum vesicles by the calcium complex of ethylene glycol bis(beta-aminoethyl ether)-N,N',-tetraacetic acid.

1982 • 33 citations

Use of monoclonal antibodies to culture rat proximal tubule cells

1986 • 32 citations

Development of a primary culture system of rat kidney cortical cells to evaluate the nephrotoxicity of xenobiotics

1986 • 32 citations

Quiescent LLC-PK1 cells as a model for cis-diamminedichloroplatinum(II) nephrotoxicity and modulation by thiol rescue agents.

1988 • 31 citations

Inhibition of prostaglandin synthesis in rat kidney perfused with and without erythrocytes: implication for analgesic nephropathy.

1986 • 31 citations

The application of renal cells in culture in studying drug-induced nephrotoxicity

1989 • 30 citations

Gentamicin-induced increases in cytosolic calcium in pig kidney cells (LLC-PK1).

1988 • 30 citations

Electrophysiological studies on primary cultures of proximal tubule cells

1986 • 30 citations

Organic cation uptake by a cultured renal epithelium

1988 • 30 citations

Primary rabbit kidney proximal tubule cell cultures maintain differentiated functions when cultured in a hormonally defined serum-free medium

1989 • 29 citations

Effects of 1,25-(OH)2D3 administered in vivo on phosphate uptake by isolated chick renal cells

1982 • 29 citations

Transporting Renal Epithelium: Culture in Hormonally Defined Serum-Free Medium

1980 • 29 citations

Genotoxicity of haloalkene and haloalkane glutathione S-conjugates in porcine kidney cells

1989 • 29 citations

Separation of proximal tubule cells from suspensions of rat kidney cells by free‐flow electrophoresis

1977 • 29 citations

Cadmium Toxicity in Kidney Cells. Resistance induced by Short Term Pretreatment in Vitro and in Vivo

1986 • 29 citations

Initiation and characterization of primary mouse kidney epithelial cultures

1988 • 28 citations

Transcytosis in cultured proximal tubular cells

1986 • 28 citations

Isolated proximal tubular cells from rat kidney as an in vitro model for studies on nephrotoxicity

1989 • 27 citations

Characterization of subclones of Madin-Darby canine kidney renal epithelial cell line

1989 • 27 citations

Single tubule perfusion techniques

1986 • 27 citations

The formation and biotransformation of cysteine conjugates of halogenated ethylenes by rabbit renal tubules

1984 • 27 citations

Evidence that stimulation of 1,25(OH)2D3 production in primary cultures of mouse kidney cells by cyclic AMP requires new protein synthesis

1987 • 27 citations

Use of monolayers of primary rat kidney cortex cells for nephrotoxicity studies

1989 • 26 citations

Kidney proximal tubular cells isolated by collagenase perfusion grow in defined media in the absence of growth factors

1987 • 26 citations

2-Bromohydroquinone-induced toxicity to rabbit renal proximal tubules: The role of biotransformation, glutathione, and covalent binding

1989 • 25 citations

Cell culture of renal epithelium derived from rabbit microdissected cortical collecting tubules

1983 • 25 citations

Primary monolayer culture of liver parenchymal cells and kidney cortical tubules as a useful new model for biochemical pharmacology and experimental toxicology

1980 • 25 citations

Metabolic heterogeneity of the proximal and distal kidney tubules

1983 • 24 citations

Potential involvement of renal transport mechanisms in nephrotoxicity

1989 • 24 citations

Cadmium nephrotoxicity in human proximal tubule cell cultures

1989 • 24 citations

Differential toxicity as a result of apical and basolateral treatment of LLC-PK1 monolayers with S-(1,2,3,4,4-pentachlorobutadienyl)glutathione and N-acetyl-S-(1,2,3,4,4-pentachlorobutadienyl)-L-cysteine

1988 • 24 citations

Cultured human proximal tubule cells as a model for aminoglycoside nephrotoxicity.

1988 • 23 citations

Isolation of cells from rabbit renal proximal tubules by using a hyperosmolar intracellular-like solution

1984 • 22 citations

Electrophysiological studies on primary cultures of proximal tubule cells

1986 • 22 citations

Cystine and lysine transport in cultured human renal epithelial cells

1987 • 21 citations

Inositol 1,4,5-trisphosphate releases Ca2+from a nonmitochondrial store site in permeabilized rat cortical kidney cells

1986 • 21 citations

Use of cultured renal epithelial cells for the study of cisplatin toxicity.

1989 • 21 citations

Techniques for isolation of brush-border and basolateral membrane vesicles from dog kidney cortex

1989 • 21 citations

Effect of Erythrocytes on the Function and Morphology of the Isolated Perfused Rat Kidney

1987 • 20 citations

Differential Toxicity of Cis and Trans Isomers of Dichlorodiammineplatinum

1988 • 20 citations

Cephaloridine toxicity in primary cultures of rat renal cortical epithelial cells

1987 • 20 citations

Establishment and characterization of an epithelial cell line, SGE1, from isolated rat renal glomeruli.

1988 • 18 citations

Restricted growth of rat kidney proximal tubule cells cultured in serum‐supplemented and defined media

1986 • 18 citations

Characteristics of cultured human renal cortical epithelia

1986 • 18 citations

Preparation of cell suspensions from tissues using collagenase and hyaluronidase, especially for measuring the electrical charges of surface membranes of mammalian cells

1966 • 18 citations

Preparation of kidney cell suspensions and respiration of kidney and liver cell suspensions

1970 • 17 citations

Primary epithelial cell culture of adult rat kidney, enhancement of cell growth by ammonium acetate

1979 • 17 citations

Quantitative requirement for ATP for active transport in isolated renal cells

1986 • 17 citations

Na+-independent sugar transport by cultured renal (LLC-PK1) epithelial cells

1989 • 16 citations

Characteristics of Na+-dependent hexose transport in OK, an established renal epithelial cell line

1989 • 16 citations

In Vitro Screens From Cns, Liver and Kidney for Systemic Toxicity

1989 • 16 citations

Active tetraethylammonium uptake across the basolateral membrane of rabbit proximal tubule

1986 • 15 citations

An electrophysiological freeze fracture assessment of cadmium nephrotoxicity in vitro

1989 • 15 citations

Comparison of glucose transport mechanisms at opposing surfaces of the renal proximal tubular cell

1986 • 14 citations

In vitro studies of mechanisms of cytotoxicity

1986 • 14 citations

Drug metabolism in isolated proximal tubule cells: aldehyde dehydrogenase.

1983 • 14 citations

An established cell line from mouse kidney medullary thick ascending limb. II. Transepithelial electrophysiology

1986 • 13 citations

A standard nomenclature for structures of the kidney

1988 • 12 citations

Polarity of the Proximal Tubular Cell: Comparison of Luminal and Contraluminal Transport Systems for Hexoses, Dicarboxylates, and Sulfate

1986 • 12 citations

Glucose transport and metabolism in rat renal proximal tubules: multicomponent effects of insulin

1986 • 12 citations

Sodium-dependent glucose transport by cultured proximal tubule cells

1987 • 12 citations

Renal anion transport

1989 • 12 citations

Growth, enzyme activity, sugar transport, and hormone supplement responses in cells cloned from a pig kidney cell line LLC‐PK1

1989 • 12 citations

Differentiated properties characteristic of renal proximal epithelium in a cell line derived from a normal monkey kidney (JTC-12)

1985 • 11 citations

Inhibition of lactate-dehydrogenase by cisplatin and other platinum-compounds: enzyme leakage of LDH is not a suitable method to measure platinum-compound-induced kidney cell damage in vitro.

1988 • 11 citations

Human and rat kidney cell metabolism of 2-acetylaminofluorene and benzo(a)pyrene.

1989 • 10 citations

Isolation of a pure suspension of proximal tubular cells from the rabbit kidney: Morphological, biochemical and metabolic assessment

1989 • 10 citations

Renal Slices and Perfusion

1987 • 10 citations

The effect of aroclor 1254 pretreatment on the phase I and phase II metabolism of 7-ethoxycoumarin in isolated viable rat kidney cells

1981 • 10 citations

Metabolic behaviour in isolated populations of proximal and distal rat renal tubules

1988 • 10 citations

Ochratoxin a decreases the activity of phosphoenolpyruvate carboxykinase and its mRNA content in primary cultures of rat kidney proximal convoluted tubule cells

1989 • 9 citations

The Contribution of Cell Culture to the Study of Renal Diseases

1988 • 9 citations

Preparative free flow electrophoresis for the isolation of two populations of proximal cells from the rabbit kidney.

1989 • 9 citations

Isolated Rat Renal Proximal Tubular Cells: A Model to Investigate Drug Induced Nephrotoxicity

1989 • 8 citations

Xenobiotic Metabolism in the Mammalian Kidney

1987 • 8 citations

Endocrine Regulation of Electrolyte Balance

1986 • 8 citations

Indirect immunoselection of late distal cell populations from rabbit kidney cortex

1986 • 8 citations

The Use of Single Nephron Techniques in Renal Toxicity Studies

1987 • 7 citations

A new stable epithelial cell line (RK-L) from normal rat kidney

1988 • 7 citations

Dependence of proximal tubule p-aminohippurate secretion on serum proteins and metabolic substrates

1986 • 6 citations

The Application of Histochemistry at the Light Microscopic Level to the Study of Nephrotoxicity

1987 • 6 citations

Metabolism of Glutathione in the Kidney

1987 • 6 citations

Characterization of Isolated Renal Proximal Tubules for Nephrotoxicity Studies

1989 • 6 citations

Biochemical and morphological characterization of primary kidney cell cultures from beige mutant mice

1987 • 5 citations

In vitro assessment of cephaloridine nephrotoxicity: Comparison of renal cortical slice and renal tubule fragment techniques

1988 • 5 citations

Metallothionein and its Involvement in Heavy Metal Induced Nephropathy

1987 • 5 citations

The Role of Glutathione in Transport Activity in Kidney

1978 • 5 citations

Dog and rat kidney proximal tubule cells in culture: Responses to parathyroid hormone

1989 • 5 citations

Changes in Rat Renal Glutaminase Activity Studied in vivo and in Primary Cultures of Proximal Convoluted Tubular Cells

2015 • 5 citations

Cystine and lysine reabsorption in the isolated perfused rat kidney

1989 • 4 citations

[66] Isolation of renal tubules

1974 • 4 citations

Lactate Oxidation by Three Segments of the Rabbit Proximal Tubule

1986 • 3 citations

PVP-sieving curves as an estimate of glomerular hemodynamics in HgCl2 acute renal failure in the dog.

1987 • 3 citations

Regulation of gluconeogenesis in swine kidney proximal tubule cells

1989 • 3 citations

Deleted Work

1955 • 0 citations