Use of monolayers of primary rat kidney cortex cells for nephrotoxicity studies

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Glutathione S-Transferases

1974 • 17,321 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

A fluorometric method for determination of oxidized and reduced glutathione in tissues

1976 • 4,013 citations

Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450

1985 • 1,272 citations

A Kinetic Photometric Method for Serum γ-Glutamyl Transpeptidase

1969 • 1,222 citations

HISTOCHEMICAL AND ULTRASTRUCTURAL DEMONSTRATION OF γ-GLUTAMYL TRANSPEPTIDASE ACTIVITY

1969 • 940 citations

Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat

1985 • 653 citations

Evaluation of cytotoxicity in cultured cells by enzyme leakage

1980 • 228 citations

The separation of glutathione transferase subunits by using reverse-phase high-pressure liquid chromatography

1987 • 186 citations

Growth and Characterization of Polarized Monolayers of Epididymal Epithelial Cells and Sertoli Cells in Dual Environment Culture Chambers

1986 • 170 citations

Use of isolated kidney cells for study of drug metabolism

1979 • 162 citations

Cytotoxicity of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine in isolated rat kidney cells.

1986 • 147 citations

Metabolism of glutathione and a glutathione conjugate by isolated kidney cells.

1979 • 140 citations

The role of glutathione conjugate metabolism and cysteine conjugate beta-lyase in the mechanism of S-cysteine conjugate toxicity in LLC-PK1 cells.

1986 • 103 citations

Effect of the organic acid transport inhibitor probenecid on renal cortical uptake and proximal tubular toxicity of hexachloro-1,3-butadiene and its conjugates*1

1985 • 98 citations

The Metabolism of Xenobiotics by Certain Extrahepatic Organs and its Relation to Toxicity*

1986 • 81 citations

Studies on the maintenance of cytochromes P‐450 and b₅, monooxygenases and cytochrome reductases in primary cultures of rat hepatocytes

1985 • 80 citations

Differential induction of rat hepatic glutathione S-transferase isoenzymes by hexachlorobenzene and benzyl isothiocyanate

1988 • 78 citations

Intestinal tissue and cell cultures

1987 • 75 citations

Effect of aminoglycoside antibiotics on cellular functions of kidney epithelial cell line (LLC-PK1): a model system for aminoglycoside nephrotoxicity.

1984 • 66 citations

The mechanism of pentachlorobutadienyl-glutathione nephrotoxicity studied with isolated rat renal epithelial cells

1986 • 66 citations

Metabolism of cadmium, zinc and copper in the rat kidney: the role of metallothionein and other binding sites.

1984 • 62 citations

Glutathione transferase isoenzymes in cultured rat hepatocytes

1988 • 56 citations

Isoenzymes of glutathione transferase in rat kidney cytosol

1985 • 55 citations

In vitro growth and differentiation of human kidney tubular cells on a basement membrane substrate

1987 • 47 citations

Rat kidney function related to tissue glutathione levels

1986 • 46 citations

Mechanisms of gentamicin transport in kidney epithelial cell line (LLC-PK1).

1986 • 43 citations

Mercapturic acid formation is an activation and intermediary step in the metabolism of hexachlorobutadiene

1986 • 42 citations

Formation of lead-induced inclusion bodies in primary rat kidney epithelial cell cultures: Effect of actinomycin D and cycloheximide

1980 • 42 citations

Disposition and nephrotoxicity of hexachloro-1,3-butadiene

1980 • 41 citations

Lipid alterations in LLC-PK1 cells exposed to mercuric chloride

1986 • 35 citations

Development of a primary culture system of rat kidney cortical cells to evaluate the nephrotoxicity of xenobiotics

1986 • 32 citations

S-(1,2-dichlorovinyl)-l-homocysteine-induced cytotoxicity in isolated rat kidney cells

1986 • 29 citations

Cytomorphological changes in liver cells exposed to allyl and benzyl isothiocyanate and their cysteine and glutathione conjugates

1986 • 27 citations

Differential toxicity as a result of apical and basolateral treatment of LLC-PK1 monolayers with S-(1,2,3,4,4-pentachlorobutadienyl)glutathione and N-acetyl-S-(1,2,3,4,4-pentachlorobutadienyl)-L-cysteine

1988 • 24 citations

Cephaloridine toxicity in primary cultures of rat renal cortical epithelial cells

1987 • 20 citations

NADPH-Cytochrome c Reductase, Cytochrome P-450 and NADPH-Linked Lipid Peroxidation in Microsomal Fractions Obtained from Rat Tissues

1976 • 18 citations

Activation and detoxification of bromobenzene in extrahepatic tissues

1984 • 17 citations

Innovative approaches for the study of cultured renal epithelia.

1986 • 11 citations