SecA suppresses the temperature-sensitive SecY24 defect in protein translocation in Escherichia coli membrane vesicles.

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

Vectors for selective expression of cloned DNAs by T7 RNA polymerase

1987 • 1,449 citations

E. coli mutant pleiotropically defective in the export of secreted proteins

1981 • 512 citations

Suppressor mutations that restore export of a protein with a defective signal sequence

1981 • 382 citations

Regulation of a membrane component required for protein secretion in escherichia coli

1982 • 356 citations

The antifolding activity of SecB promotes the export of the E. coli maltose-binding protein

1988 • 326 citations

Mutations in a new gene, secB, cause defective protein localization in Escherichia coli

1983 • 270 citations

Trigger factor: a soluble protein that folds pro-OmpA into a membrane-assembly-competent form.

1987 • 257 citations

A defined mutation in the protein export gene within the spc ribosomal protein operon of Escherichia coli: isolation and characterization of a new temperature-sensitive secY mutant.

1984 • 216 citations

Nucleotide sequence of the secA gene and secA(Ts) mutations preventing protein export in Escherichia coli

1988 • 188 citations

Export of Protein: A Biochemical View

1987 • 184 citations

secD, a new gene involved in protein export in Escherichia coli

1987 • 173 citations

ATP is essential for protein translocation into Escherichia coli membrane vesicles.

1985 • 163 citations

Importance of secondary structure in the signal sequence for protein secretion.

1983 • 152 citations

A mutation affecting the regulation of a secA-lacZ fusion defines a new sec gene.

1988 • 143 citations

Both ATP and the electrochemical potential are required for optimal assembly of pro-OmpA into Escherichia coli inner membrane vesicles.

1986 • 142 citations

Cloning and restriction mapping of the alkaline phosphatase structural gene (phoA) of Escherichia coli and generation of deletion mutants in vitro

1981 • 126 citations

Effects of Escherichia coli secB mutations on pre-maltose binding protein conformation and export kinetics.

1988 • 117 citations

Kinetic analysis of lamB mutants suggests the signal sequence plays multiple roles in protein export.

1986 • 107 citations

Protein export in Escherichia coli requires a soluble activity.

1984 • 100 citations

Alkaline phosphatase and OmpA protein can be translocated posttranslationally into membrane vesicles of Escherichia coli

1985 • 98 citations

Energy-requiring translocation of the OmpA protein and alkaline phosphatase of Escherichia coli into inner membrane vesicles

1984 • 74 citations

Proper interaction between at least two components is required for efficient export of proteins to the Escherichia coli cell envelope

1985 • 74 citations

Suppression of growth and protein secretion defects in Escherichia coli secA mutants by decreasing protein synthesis

1986 • 69 citations

Biochemical evidence for the secY24 defect in Escherichia coli protein translocation and its suppression by soluble cytoplasmic factors.

1987 • 56 citations

The secY protein can act post-translationally to promote bacterial protein export.

1986 • 50 citations

The use of extragenic suppressors to define genes involved in protein export in Escherichia coli

1984 • 49 citations

Genetic Studies on Protein Export in Bacteria

1986 • 45 citations

Altered translation initiation factor 2 in the cold-sensitive ssyG mutant affects protein export in Escherichia coli.

1986 • 40 citations

Requirement of heat-labile cytoplasmic protein factors for posttranslational translocation of OmpA protein precursors into Escherichia coli membrane vesicles

1988 • 31 citations

Biochemical Studies of Bacterial Protein Export

1986 • 18 citations

prlA-mediated suppression of signal sequence mutations is modulated by the secA gene product of Escherichia coli K-12

1985 • 16 citations