Biochemical evidence for the secY24 defect in Escherichia coli protein translocation and its suppression by soluble cytoplasmic factors.

EFFECT OF TEMPERATURE ON THE COMPOSITION OF FATTY ACIDS IN ESCHERICHIA COLI

1962 • 735 citations

Multiple Mechanisms of Protein Insertion into and Across Membranes

1985 • 720 citations

THE GENETICS AND REGULATION OF HEAT-SHOCK PROTEINS

1984 • 648 citations

E. coli mutant pleiotropically defective in the export of secreted proteins

1981 • 512 citations

GENETIC ANALYSIS OF PROTEIN EXPORT IN ESCHERICHIA COLI K12

1985 • 432 citations

Suppressor mutations that restore export of a protein with a defective signal sequence

1981 • 382 citations

The mechanism of protein secretion across membranes

1980 • 285 citations

Thespcrtbosomal protein operon ofEschenchia coli:sequence and cotranscriptlon of the rlbosomal protein genes and a protein export gene

1983 • 258 citations

A defined mutation in the protein export gene within the spc ribosomal protein operon of Escherichia coli: isolation and characterization of a new temperature-sensitive secY mutant.

1984 • 216 citations

Effects of the complete removal of basic amino acid residues from the signal peptide on secretion of lipoprotein in Escherichia coli.

1983 • 214 citations

Conditional-lethal mutations that suppress genetic defects in morphogenesis by altering structural proteins.

1975 • 212 citations

Transient regulation of protein synthesis in Escherichia coli upon shift-up of growth temperature

1978 • 181 citations

In vitro translocation of bacterial proteins across the plasma membrane of Escherichia coli.

1984 • 174 citations

secD, a new gene involved in protein export in Escherichia coli

1987 • 173 citations

ATP is essential for protein translocation into Escherichia coli membrane vesicles.

1985 • 163 citations

Importance of secondary structure in the signal sequence for protein secretion.

1983 • 152 citations

Both ATP and the electrochemical potential are required for optimal assembly of pro-OmpA into Escherichia coli inner membrane vesicles.

1986 • 142 citations

The SecY membrane component of the bacterial protein export machinery: analysis by new electrophoretic methods for integral membrane proteins.

1985 • 129 citations

Escherichia coli mutants accumulating the precursor of a secreted protein in the cytoplasm

1979 • 129 citations

Localization and processing of outer membrane and periplasmic proteins in Escherichia coli strains harboring export-specific suppressor mutations.

1982 • 124 citations

Identification of the secY (prlA) gene product involved in protein export in Escherichia coli

1984 • 119 citations

Kinetic analysis of lamB mutants suggests the signal sequence plays multiple roles in protein export.

1986 • 107 citations

Protein export in Escherichia coli requires a soluble activity.

1984 • 100 citations

Alkaline phosphatase and OmpA protein can be translocated posttranslationally into membrane vesicles of Escherichia coli

1985 • 98 citations

Export of protein in bacteria

1984 • 96 citations

Energy-requiring translocation of the OmpA protein and alkaline phosphatase of Escherichia coli into inner membrane vesicles

1984 • 74 citations

The synthesis of export-defective proteins can interfere with normal protein export in Escherichia coli.

1984 • 73 citations

Suppression of growth and protein secretion defects in Escherichia coli secA mutants by decreasing protein synthesis

1986 • 69 citations

Mutation that suppresses the protein export defect of the secY mutation and causes cold-sensitive growth of Escherichia coli

1984 • 54 citations

Properties of initiation-free polysomes of Escherichia coli

1973 • 53 citations

The secY protein can act post-translationally to promote bacterial protein export.

1986 • 50 citations

Identification of five new essential genes involved in the synthesis of a secreted protein in Escherichia coli

1985 • 49 citations

The use of extragenic suppressors to define genes involved in protein export in Escherichia coli

1984 • 49 citations

Suppressors of the secY24 mutation: identification and characterization of additional ssy genes in Escherichia coli

1986 • 49 citations

Genetic Studies on Protein Export in Bacteria

1986 • 45 citations

Altered translation initiation factor 2 in the cold-sensitive ssyG mutant affects protein export in Escherichia coli.

1986 • 40 citations

Protein translocation into Escherichia coli membrane vesicles is inhibited by functional synthetic signal peptides.

1987 • 40 citations

Translocation of nascent non-signal sequence protein in heated Escherichia coli.

1986 • 28 citations

Signal Peptidases

1986 • 22 citations

Lack of Effect of Leader Peptidase Overproduction on the Processing in vivo of Exported Proteins in Escherichia coli

1986 • 21 citations

Biochemical Studies of Bacterial Protein Export

1986 • 18 citations