In vitro fusion of endocytic vesicles is inhibited by cyclin A-cdc2 kinase.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

Cyclin is degraded by the ubiquitin pathway

1991 • 2,355 citations

Cyanobacterial microcystin‐LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants

1990 • 1,627 citations

Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

1983 • 1,506 citations

Cyclin A is required at two points in the human cell cycle.

1992 • 1,380 citations

Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

1989 • 1,237 citations

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

1989 • 1,114 citations

The nuclear envelope lamina is reversibly depolymerized during mitosis

1980 • 956 citations

Isolation of a human cyclin cDNA: Evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

1989 • 920 citations

Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport.

1991 • 858 citations

Cyclin activation of p34cdc2

1990 • 690 citations

cdc2 protein kinase is complexed with both cyclin A and B: Evidence for proteolytic inactivation of MPF

1989 • 666 citations

THE ULTRASTRUCTURE OF A MAMMALIAN CELL DURING THE MITOTIC CYCLE

1964 • 567 citations

The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes

1986 • 534 citations

Histone Phosphorylation and Chromatin Structure during Mitosis in Chinese Hamster Cells

1978 • 534 citations

Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates.

1991 • 502 citations

Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes

1991 • 493 citations

The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases

1989 • 486 citations

Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function.

1991 • 459 citations

The roles of Drosophila cyclins A and B in mitotic control

1990 • 429 citations

SURFACE SPECIALIZATIONS OF ABSORBING CELLS

1965 • 420 citations

Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts.

1992 • 419 citations

The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle.

1990 • 377 citations

Membrane Traffic in Endocytosis: Insights from Cell-Free Assays

1989 • 369 citations

A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex

1992 • 361 citations

cdc2 phosphorylation is required for its interaction with cyclin.

1991 • 338 citations

Fission yeast p13 blocks mitotic activation and tyrosine dephosphorylation of the Xenopus cdc2 protein kinase

1989 • 327 citations

Dephosphorylation and activation of Xenopusp34cdc2 protein kinase during the cell cycle

1989 • 300 citations

Xenopus M phase MAP kinase: isolation of its cDNA and activation by MPF.

1991 • 274 citations

A new human p34 protein kinase, CDK2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Eg1.

1991 • 265 citations

The A- and B-type cyclins of Drosophila are accumulated and destroyed in temporally distinct events that define separable phases of the G2-M transition.

1990 • 262 citations

Vesicle fusion following receptor-mediated endocytosis requires a protein active in Golgi transport

1989 • 250 citations

Activation of human cyclin-dependent kinases in vitro.

1992 • 242 citations

Mitotic Golgi fragments in HeLa cells and their role in the reassembly pathway.

1989 • 242 citations

The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product

1990 • 222 citations

Molecular cloning and characterization of the mRNA for cyclin from sea urchin eggs.

1987 • 220 citations

cdc25+ encodes a protein phosphatase that dephosphorylates p34cdc2.

1992 • 211 citations

Synergistic action of Drosophila cyclins A and B during the G2-M transition.

1993 • 211 citations

Both cyclin A delta 60 and B delta 97 are stable and arrest cells in M-phase, but only cyclin B delta 97 turns on cyclin destruction.

1991 • 196 citations

Identification of the domains in cyclin A required for binding to, and activation of, p34cdc2 and p32cdk2 protein kinase subunits.

1992 • 191 citations

Surface functions during mitosis I: Phagocytosis, pinocytosis and mobility of surface-bound ConA

1978 • 185 citations

A mitotic form of the Golgi apparatus in HeLa cells

1987 • 183 citations

Cyclin B in Xenopus oocytes: implications for the mechanism of pre-MPF activation.

1991 • 176 citations

Inhibition of endocytic vesicle fusion in vitro by the cell-cycle control protein kinase cdc2

1989 • 167 citations

Activation of human CDC2 protein as a histone H1 kinase is associated with complex formation with the p62 subunit.

1989 • 148 citations

Control of programmed cyclin destruction in a cell-free system.

1989 • 138 citations

Fusion between endocytic vesicles in a cell-free system.

1987 • 133 citations

Recycling of transferrin receptors in A431 cells is inhibited during mitosis.

1984 • 128 citations

Reconstitution of an endocytic fusion event in a cell-free system

1985 • 120 citations

Activation of p34cdc2 kinase by cyclin A.

1991 • 111 citations

Newly synthesized G protein of vesicular stomatitis virus is not transported to the Golgi complex in mitotic cells.

1985 • 107 citations

Formation of coated vesicles from coated pits in broken A431 cells.

1989 • 105 citations

Cyclin A- and cyclin B-dependent protein kinases are regulated by different mechanisms in Xenopus egg extracts.

1992 • 91 citations

Cell-free fusion of endocytic vesicles is regulated by phosphorylation.

1992 • 87 citations

Analysis of transferrin recycling in mitotic and interphase hela cells by quantitative fluorescence microscopy

1984 • 80 citations

Sex, maps, and imprinting

1991 • 78 citations

Cyclin A potentiates maturation-promoting factor activation in the early Xenopus embryo via inhibition of the tyrosine kinase that phosphorylates cdc2.

1992 • 75 citations

Fusion between vesicles from the pathway of receptor‐mediated endocytosis in a cell‐free system

1988 • 71 citations

Requirement for p34cdc2 kinase is restricted to mitosis in the mammalian cdc2 mutant FT210

1992 • 65 citations

Sphingolipid transport in mitotic HeLa cells.

1992 • 62 citations

Inhibition of intra-Golgi transport in vitro by mitotic kinase.

1993 • 49 citations

Coated pits in interphase and mitotic A431 cells.

1987 • 49 citations

Cyclin A-cdc2 kinase does not trigger but delays cyclin degradation in interphase extracts of amphibian eggs

1992 • 47 citations

The secretory pathway is blocked between the trans-Golgi and the plasma membrane during meiotic maturation in Xenopus oocytes

1990 • 45 citations

Isolation of functional, coated, endocytic vesicles.

1991 • 42 citations

Inhibition of membrane fusion in vitro via cyclin B but not cyclin A.

1992 • 41 citations

Membrane traffic between secretory compartments is differentially affected during mitosis.

1990 • 37 citations

Cell-free assays and the mechanism of receptor-mediated endocytosis

1988 • 33 citations

Chapter 9 Automated Cell Cycle Analysis

1975 • 24 citations

Protein transport from endoplasmic reticulum to the Golgi complex can occur during meiotic metaphase in Xenopus oocytes.

1989 • 21 citations

Chapter 11 Fusion of Endocytic Vesicles in a Cell-Free System

1989 • 16 citations

The cell cycle dependence of the secretory pathway in developing Xenopus laevis

1991 • 9 citations