Induction of −2 frameshift mutations within alternating GC sequences by carcinogens that bind to the C8 position of guanine residues Development of a specific mutation assay

8-(N-2-Fluorenylacetamido) guanosine, an Arylamidation Reaction Product of Guanosine and the Carcinogen N-Acetoxy-N-2-fluorenylacetamide in Neutral Solution^*

1967 • 335 citations

Proteins required for ultraviolet light and chemical mutagenesis

1983 • 279 citations

Carcinogen-induced mutation spectrum in wild-type, uvrA and umuC strains of Escherichia coli

1984 • 183 citations

Chemical Carcinogens as Frameshift Mutagens: Salmonella DNA Sequence Sensitive to Mutagenesis by Polycyclic Carcinogens

1974 • 169 citations

Hot spots of frameshift mutations induced by the ultimate carcinogen N- acetoxy-N-2-acetylaminofluorene

1981 • 164 citations

Potent novel mutagens produced by broiling fish under normal conditions.

1980 • 154 citations

DNA binding and mutation spectra of the carcinogen N-2-aminofluorene in Escherichia coli

1985 • 146 citations

Induction of the Z conformation in poly(dG-dC).poly(dG-dC) by binding of N-2-acetylaminofluorene to guanine residues.

1981 • 143 citations

Single adduct mutagenesis: strong effect of the position of a single acetylaminofluorene adduct within a mutation hot spot.

1989 • 141 citations

Isolation and structure determination of mutagenic substances in L-glutamic acid pyrolysate.

1978 • 139 citations

Conformation of poly(dG-dC) . poly(dG-dC) modified by the carcinogens N-acetoxy-N-acetyl-2-aminofluorene and N-hydroxy-N-2-aminofluorene.

1980 • 129 citations

On the interaction of N-2-fluorenylhydroxylamine with nucleic acids in, vitro

1965 • 117 citations

Sensitivity of the conformation of deoxyguanosine to bind ing at the C-8 position by N-acetylated and unacetylated 2-aminofluorene

1980 • 89 citations

Z-DNA-forming sequences are spontaneous deletion hot spots.

1989 • 87 citations

Adducts from in vivo action of the carcinogen 4-hydroxyaminoquinoline 1-oxide in rats and from in vitro reaction of 4-acetoxyaminoquinoline 1-oxide with DNA and polynucleotides.

1985 • 69 citations

Comparative studies on the 7-iodo and 7-fluoro derivatives of N-acetoxy-N-2-acetylaminofluorene: binding sites on DNA and conformational change of modified deoxytrinucleotides

1978 • 56 citations

Genetical Studies on the Lipopolysaccharide Structure of Escherichia coli K12

1973 • 46 citations

Base-change analysis of revertants of the hisD3052 allele in Salmonella typhimurium

1988 • 46 citations

Strong structural effect of the position of a single acetylaminofluorene adduct within a mutation hot spot

1989 • 44 citations

Construction of frameshift mutation hot spots within the tetracycline resistance gene of pBR322

1985 • 30 citations

Genetic control of AAF-induced mutagenesis at alternating GC sequences: An additional role for RecA

1989 • 29 citations

Synthesis and mutagenic activity of nitro-imidazoarenes. A study on the mechanism of the genotoxicity of heterocydic arylamines and nitroarenes

1988 • 25 citations

Different levels of induction ofRecAprotein inE. coli(PQ 10) after treatment with two related carcinogens

1983 • 18 citations

Conformations of poly(dG-dC).poly(dG-dC) modified by the O-acetyl derivative of the carcinogen 4-hydroxyaminoquinoliue 1-oxide

1984 • 14 citations

Reaction of DNA with a mutagenic 3-N, N-acetoxyacetylamino-4, 6-dimethyldipyrido[1, 2-a:3′, 2′-d]imidazole (N-AcO-AGlu-P-3) related to glutamic acid pyrolysates

1985 • 13 citations

DNA sequence analysis of mutations induced by N-2-acetylamino-7-iodofluorene in plasmid pBR322 in Escherichia coli

1990 • 10 citations

Conformational changes induced in DNA by thein vitroreaction with the mutagenic amine: 3-N,N-acetoxyacetylainnio-4,6-dimethryldipyrido (l,2-a:3′,2′-d) imidazole

1984 • 10 citations

Base pair substitution and frameshift mutagenesis induced by apurinic sites and two fluorene derivatives in a recA 441 lexA (Def) strain

1986 • 10 citations

Mutagenic heterocyclic nitrogen compounds related to protein pyrolysates. V. Electron impact fragmentation of L‐glutamic acid and related dipyrido[1,2‐a:3′,2′‐d]imidazoles

1986 • 9 citations

Mutation spectrum of the mutagen 3-N,N-acetoxyacetylamino-4,6-dimethyldipyrido[1,2-a:3′,2′-d]imidazole in Escherichia coli

1988 • 5 citations

Increased sensitivity of Escherichia coli K12 to certain mutagens as a consequence of a mutation leading to phage U3 resistance

1982 • 3 citations

Synthesis and mutagenic activity of nitroimidazoarenes. A study on the mechanism of the genotoxic activity of IQ-like heterocyclic arylamines

1988 • 3 citations

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