Single adduct mutagenesis: strong effect of the position of a single acetylaminofluorene adduct within a mutation hot spot.

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

1975 • 3,362 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

Complete Nucleotide Sequence of the Escherichia coli Plasmid pBR322

1979 • 1,807 citations

Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli

1984 • 1,608 citations

The SOS regulatory system of Escherichia coli

1982 • 1,491 citations

pEMBL: a new family of single stranded plasmids

1983 • 1,231 citations

In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome.

1984 • 437 citations

Carcinogens as Frameshift Mutagens: Metabolites and Derivatives of 2-Acetylaminofluorene and Other Aromatic Amine Carcinogens

1972 • 361 citations

8-(N-2-Fluorenylacetamido) guanosine, an Arylamidation Reaction Product of Guanosine and the Carcinogen N-Acetoxy-N-2-fluorenylacetamide in Neutral Solution^*

1967 • 335 citations

Carcinogen-induced mutation spectrum in wild-type, uvrA and umuC strains of Escherichia coli

1984 • 183 citations

Chemical Carcinogens as Frameshift Mutagens: Salmonella DNA Sequence Sensitive to Mutagenesis by Polycyclic Carcinogens

1974 • 169 citations

Hot spots of frameshift mutations induced by the ultimate carcinogen N- acetoxy-N-2-acetylaminofluorene

1981 • 164 citations

Mechanisms and consequences of DNA damage processing

1987 • 152 citations

DNA binding and mutation spectra of the carcinogen N-2-aminofluorene in Escherichia coli

1985 • 146 citations

Induction of the Z conformation in poly(dG-dC).poly(dG-dC) by binding of N-2-acetylaminofluorene to guanine residues.

1981 • 143 citations

Changes in DNA base sequence induced by targeted mutagenesis of lambda phage by ultraviolet light

1984 • 141 citations

Mechanisms of ultraviolet-induced mutation

1987 • 130 citations

Conformation of poly(dG-dC) . poly(dG-dC) modified by the carcinogens N-acetoxy-N-acetyl-2-aminofluorene and N-hydroxy-N-2-aminofluorene.

1980 • 129 citations

DNA binding spectrum of the carcinogen N-acetoxy-N-2-acetylaminofluorene significantly differs from the mutation spectrum

1984 • 96 citations

Sequence analysis of ultraviolet-induced mutations in M13lacZ hybrid phage DNA

1984 • 96 citations

Spectroscopic studies on acetylaminofluorene-modified (dT-dG)n . (dC-dA)n suggest a left-handed conformation.

1982 • 89 citations

Conformational changes of poly(dG-dC). poly(dG-dC) modified by the carcinogen N-acetoxy-N-acetyl-2-aminofluorene

1981 • 74 citations

Conformation of the deoxydinucleoside monophosphate dCpdG modified at carbon 8 of guanine with 2-(acetylamino)fluorene

1982 • 66 citations

Specific strand loss in N-2-acetylaminofluorene-modified DNA

1987 • 66 citations

Excision repair of ultraviolet-irradiated deoxyribonucleic acid in plasmolyzed cells of Escherichia coli

1976 • 60 citations

Z-DNA conformation of N-2-acetylaminofluorene modified poly(dG-dC)·poly(dG-dC) determined by reactivity with anti cytidine antibodies and minimized potential energy calculations

1981 • 55 citations

Targeted mutations induced by a single acetylaminofluorene DNA adduct in mammalian cells and bacteria.

1988 • 43 citations

Specificity of mutagenesis by 4-aminobiphenyl. A possible role for N-(deoxyadenosin-8-yl)-4-aminobiphenyl as a premutational lesion.

1988 • 38 citations

Construction of frameshift mutation hot spots within the tetracycline resistance gene of pBR322

1985 • 30 citations

Deoxyhexanucleotide containing a vinyl chloride induced DNA lesion, 1,N6-ethenoadenine: synthesis, physical characterization, and incorporation into a duplex bacteriophage M13 genome as part of an amber codon

1987 • 28 citations

Specificity of N-acetoxy-N-2-acetylaminofluorene-induced frameshift mutation spectrum in mismatch repair deficient Escherichia coli strains mutH, L, S and U

1986 • 9 citations

Construction of plasmids carrying lacI mutations

1985 • 6 citations