Genetic control of AAF-induced mutagenesis at alternating GC sequences: An additional role for RecA

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli

1984 • 1,608 citations

The SOS regulatory system of Escherichia coli

1982 • 1,491 citations

Frameshift Mutations and the Genetic Code

1966 • 1,400 citations

Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli.

1984 • 743 citations

MUTANTS OF ESCHERICHIA COLI K-12 DEFECTIVE IN DNA REPAIR AND IN GENETIC RECOMBINATION

1966 • 635 citations

RECOMBINATION DEFICIENT MUTANTS OF E. COLI AND OTHER BACTERIA

1973 • 568 citations

Isolation and characterization of mutants of Escherichia coli deficient in induction of mutations by ultraviolet light

1977 • 567 citations

RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and posttranslational activation.

1988 • 415 citations

UmuD mutagenesis protein of Escherichia coli: overproduction, purification, and cleavage by RecA.

1988 • 354 citations

RecA protein-dependent cleavage of UmuD protein and SOS mutagenesis.

1988 • 349 citations

8-(N-2-Fluorenylacetamido) guanosine, an Arylamidation Reaction Product of Guanosine and the Carcinogen N-Acetoxy-N-2-fluorenylacetamide in Neutral Solution^*

1967 • 335 citations

Dominant Mutations ( lex ) in Escherichia coli K-12 Which Affect Radiation Sensitivity and Frequency of Ultraviolet Light-Induced Mutations

1972 • 310 citations

MECHANISMS OF SPONTANEOUS AND INDUCED FRAMESHIFT MUTATION IN BACTERIOPHAGE T4

1985 • 292 citations

Uvm mutants of Escherichia coli K 12 deficient in UV mutagenesis

1978 • 233 citations

A mutant of Escherichia coli showing constitutive expression of the lysogenic induction and error-prone DNA repair pathways.

1977 • 231 citations

Physical studies on deoxyribonucleic acid after covalent binding of a carcinogen

1972 • 187 citations

Carcinogen-induced mutation spectrum in wild-type, uvrA and umuC strains of Escherichia coli

1984 • 183 citations

Hot spots of frameshift mutations induced by the ultimate carcinogen N- acetoxy-N-2-acetylaminofluorene

1981 • 164 citations

Induction of the Z conformation in poly(dG-dC).poly(dG-dC) by binding of N-2-acetylaminofluorene to guanine residues.

1981 • 143 citations

Genetic and sequence analysis of frameshift mutations induced by ICR-191

1981 • 130 citations

Conformation of poly(dG-dC) . poly(dG-dC) modified by the carcinogens N-acetoxy-N-acetyl-2-aminofluorene and N-hydroxy-N-2-aminofluorene.

1980 • 129 citations

Role of RecA protein in untargeted UV mutagenesis of bacteriophage lambda: evidence for the requirement for the dinB gene.

1986 • 128 citations

Constitutive expression of SOS functions and modulation of mutagenesis resulting from resolution of genetic instability at or near the recA locus of Escherichia coli

1982 • 124 citations

Dual role for Escherichia coli RecA protein in SOS mutagenesis.

1985 • 123 citations

Comparative orientation of the fluorene residue in native DNA modified by N-acetoxy-N-2-acetylaminofluorene and two 7-halogeno derivatives

1976 • 123 citations

In vitro recognition of carcinogen-induced local denaturation sites in native DNA by S1 endonuclease from Aspergillus oryzae

1975 • 119 citations

Influence of RecA protein on induced mutagenesis

1982 • 108 citations

Involvement of the activated form of RecA protein in SOS mutagenesis and stable DNA replication in Escherichia coli.

1984 • 108 citations

DNA binding spectrum of the carcinogen N-acetoxy-N-2-acetylaminofluorene significantly differs from the mutation spectrum

1984 • 96 citations

Characterization of lexB mutations in Escherichia coli K-12

1977 • 95 citations

Uvm mutants of Escherichia coli K12 deficient in UV mutagenesis

1979 • 93 citations

Spectroscopic studies on acetylaminofluorene-modified (dT-dG)n . (dC-dA)n suggest a left-handed conformation.

1982 • 89 citations

Two mutations that alter the regulatory activity of E. coli recA protein

1981 • 77 citations

Left-handed Z-DNA binding by the recA protein of Escherichia coli.

1987 • 76 citations

Conformational changes of poly(dG-dC). poly(dG-dC) modified by the carcinogen N-acetoxy-N-acetyl-2-aminofluorene

1981 • 74 citations

Specific strand loss in N-2-acetylaminofluorene-modified DNA

1987 • 66 citations

Comparative studies on the 7-iodo and 7-fluoro derivatives of N-acetoxy-N-2-acetylaminofluorene: binding sites on DNA and conformational change of modified deoxytrinucleotides

1978 • 56 citations

Z-DNA conformation of N-2-acetylaminofluorene modified poly(dG-dC)·poly(dG-dC) determined by reactivity with anti cytidine antibodies and minimized potential energy calculations

1981 • 55 citations

Isolation and characterization of amber mutations in the lexA gene of Escherichia coli K-12

1979 • 51 citations

Electron microscopic visualization of N-acetoxy-N-2-acetylaminofluorene binding sites in ColE1 DNA by means of specific antibodies.

1979 • 47 citations

Effect of umuC mutations on targeted and untargeted ultraviolet mutagenesis in bacteriophage λ

1984 • 35 citations

Construction of frameshift mutation hot spots within the tetracycline resistance gene of pBR322

1985 • 30 citations

The genetic characterization of lexB32, lexB33 and lexB35 mutations of Escherichia coli: Location and complementation pattern for UV resistance

1977 • 20 citations

Activated RecA protein may induce expression of a gene that is not controlled by the LexA repressor and whose function is required for mutagenesis and repair of UV-irradiated bacteriophage lambda

1987 • 18 citations

Base pair substitution and frameshift mutagenesis induced by apurinic sites and two fluorene derivatives in a recA 441 lexA (Def) strain

1986 • 10 citations

Specificity of N-acetoxy-N-2-acetylaminofluorene-induced frameshift mutation spectrum in mismatch repair deficient Escherichia coli strains mutH, L, S and U

1986 • 9 citations