Antimetastatic Activity of Polymeric RGDT Peptides Conjugated with Poly(ethylene glycol)

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

1984 • 3,580 citations

Arg-Gly-Asp: A versatile cell recognition signal

1986 • 1,413 citations

Tumor invasion and the extracellular matrix.

1983 • 960 citations

BIOCHEMICAL INTERACTIONS OF TUMOR CELLS WITH THE BASEMENT MEMBRANE

1986 • 693 citations

Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene.

1985 • 659 citations

A Synthetic Peptide from Fibronectin Inhibits Experimental Metastasis of Murine Melanoma Cells

1986 • 634 citations

YIGSR, a Synthetic Laminin Pentapeptide, Inhibits Experimental Metastasis Formation

1987 • 555 citations

Tumor cell instability, diversification, and progression to the metastatic phenotype: from oncogene to oncofetal expression.

1987 • 508 citations

The tetrapeptide analogue of the cell attachment site of fibronectin inhibits platelet aggregation and fibrinogen binding to activated platelets.

1985 • 437 citations

Complete amino acid sequence of human vitronectin deduced from cDNA. Similarity of cell attachment sites in vitronectin and fibronectin.

1985 • 418 citations

Sequence of the cDNA encoding the laminin B1 chain reveals a multidomain protein containing cysteine-rich repeats.

1987 • 381 citations

The selection and characterization of an invasive variant of the B16 melanoma.

1979 • 376 citations

Laminin and fibronectin promote the haptotactic migration of B16 mouse melanoma cells in vitro.

1984 • 314 citations

The laminin B2 chain has a multidomain structure homologous to the B1 chain.

1987 • 307 citations

?Seed and soil? revisited: mechanisms of site-specific metastasis

1982 • 276 citations

Cancer invasion and metastasis : biologic and therapeutic aspects

1984 • 221 citations

Basement Membrane and the Invasive Activity of Metastatic Tumor Cells

1986 • 209 citations

Investigation of the biological effects of anti-cell adhesive synthetic peptides that inhibit experimental metastasis of B16-F10 murine melanoma cells.

1988 • 175 citations

Identification of a second active site in laminin for promotion of cell adhesion and migration and inhibition of in vivo melanoma lung colonization

1989 • 127 citations

Effect of cyclic RGD peptide on cell adhesion and tumor metastasis

1991 • 126 citations

Inhibition of the metastasis of murine malignant melanoma by synthetic polymeric peptides containing core sequences of cell-adhesive molecules.

1989 • 125 citations

Enhanced lymphatic delivery of mitomycin C conjugated with dextran.

1984 • 92 citations

Peptides containing the cell-attachment recognition signal Arg-Gly-Asp prevent gastrulation in Drosophila embryos

1987 • 88 citations

Antimetastatic effects of synthetic polypeptides containing repeated structures of the cell adhesive Arg-Gly-Asp (RGD) and Tyr-Ile-Gly-Ser-Arg (YIGSR) sequences

1989 • 83 citations

The inhibition of murine lung metastasis by synthetic polypeptides [poly(arg-gly-asp) and poly(tyr-ile-gly-ser-arg)] with a core sequence of cell adhesion molecules

1989 • 73 citations

Correlation of Inhibition of Adhesion of Large Cell Lymphoma and Hepatic Sinusoidal Endothelial Cells by RGD-Containing Peptide Polymers with Metastatic Potential: Role of Integrin-Dependent and -Independent Adhesion Mechanisms

1989 • 53 citations

The Ernst W. Bertner Memorial Award lecture: the evolution of biological heterogeneity in metastatic neoplasms.

1983 • 49 citations

Anti‐metastatic and Anti‐invasive Effects of Polymeric Arg‐Gly‐Asp (RGD) Peptide, Poly(RGD), and Its Analogues

1990 • 48 citations

Synthesis of antitumor‐active conjugates of adriamycin or daunomycin with the copolymer of divinyl ether and maleic anhydride

1986 • 42 citations

Synthesis of poly(ethylene glycol)‐bound 3‐(5‐fluorouracil‐1‐yl)propanoic acid, its hydrolysis reactivity and antitumor activity

1985 • 34 citations

Recombinant Fusion Polypeptide with Cell‐ and Heparin‐binding Domains of Fibronectin Inhibits Liver Metastasis of L5178Y‐ML25 Lymphoma Cells

1991 • 20 citations

Synthetic polymers as targetable carries for drugs

1984 • 14 citations