Basement Membrane and the Invasive Activity of Metastatic Tumor Cells

Metastasis Results from Preexisting Variant Cells Within a Malignant Tumor

1977 • 1,422 citations

Role of collagenous matrices in the adhesion and growth of cells.

1981 • 1,375 citations

Selection of Successive Tumour Lines for Metastasis

1973 • 1,360 citations

CELL SURFACE INTERACTIONS WITH EXTRACELLULAR MATERIALS

1983 • 1,147 citations

Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor

1985 • 1,119 citations

Tumor invasion and the extracellular matrix.

1983 • 960 citations

A Network Model for the Organization of Type IV Collagen Molecules in Basement Membranes

1981 • 889 citations

Tumor heterogeneity and the biology of cancer invasion and metastasis.

1978 • 833 citations

Shapes, domain organizations and flexibility of laminin and fibronectin, two multifunctional proteins of the extracellular matrix

1981 • 666 citations

Role of laminin in the attachment of PAM 212 (epithelial) cells to basement membrane collagen

1980 • 661 citations

Increased permeability of the glomerular basement membrane to ferritin after removal of glycosaminoglycans (heparan sulfate) by enzyme digestion.

1980 • 650 citations

Cell-Surface Glycosaminoglycans

1984 • 552 citations

Localization of type IV collagen, laminin, heparan sulfate proteoglycan, and fibronectin to the basal lamina of basement membranes.

1982 • 464 citations

Preferential digestion of basement membrane collagen by an enzyme derived from a metastatic murine tumor.

1979 • 452 citations

Isolation of a cell surface receptor protein for laminin from murine fibrosarcoma cells.

1983 • 441 citations

Isolation of a tumor cell laminin receptor

1983 • 426 citations

Laminin receptor on human breast carcinoma cells.

1983 • 419 citations

Role of laminin in the attachment and metastasis of murine tumor cells.

1982 • 334 citations

?Seed and soil? revisited: mechanisms of site-specific metastasis

1982 • 276 citations

Arrest and metastasis of blood-borne tumor cells are modified by fusion of plasma membrane vesicles from highly metastatic cells.

1980 • 261 citations

Migration by haptotaxis of a Schwann cell tumor line to the basement membrane glycoprotein laminin.

1983 • 259 citations

Modulation of the Metastatic Activity of Melanoma Cells by Laminin and Fibronectin

1984 • 258 citations

Proteoglycans: structure and function

1990 • 238 citations

The role of cell adhesion proteins?laminin and fibronectin?in the movement of malignant and metastatic cells

1985 • 236 citations

Establishment of mouse colonic carcinoma cell lines with different metastatic properties.

1980 • 228 citations

Destruction of extracellular matrices containing glycoproteins, elastin, and collagen by metastatic human tumor cells.

1980 • 221 citations

Respective roles of laminin and fibronectin in adhesion of human carcinoma and sarcoma cells

1981 • 218 citations

New method for preparing large surfaces of intact human basement membrane for tumor invasion studies

1980 • 207 citations

Organ specificity of blood-borne tumour metastasis determined by cell adhesion?

1975 • 207 citations

Synthesis and effects of basement membrane components in cultured rat Schwann cells

1984 • 198 citations

Binding of laminin to type IV collagen: a morphological study.

1985 • 196 citations

The significance of the circulating cancer cell

1975 • 196 citations

Metastatic tumor cell attachment and invasion assay utilizing vascular endothelial cell monolayers.

1982 • 187 citations

Laminin molecular domains which alter metastasis in a murine model.

1984 • 187 citations

Isolation of a subunit of laminin and its role in molecular structure and tumor cell attachment.

1982 • 182 citations

The implications of tumor heterogeneity for studies on the biology and therapy of cancer metastasis

1981 • 182 citations

Cell surface-associated proteins which bind native type IV collagen or gelatin.

1984 • 180 citations

Degradation of Basement Membrane by Murine Tumor Cells2

1977 • 156 citations

Expression of laminin receptor in normal and carcinomatous human tissues as defined by a monoclonal antibody.

1985 • 150 citations

Effects of detergent solubilization on the hyaluronate-binding protein from membranes of simian virus 40-transformed 3T3 cells.

1983 • 141 citations

Migration of tumor cells to organ-derived chemoattractants.

1985 • 135 citations

Ultrastructure of Reichert's membrane, a multilayered basement membrane in the parietal wall of the rat yolk sac.

1983 • 132 citations

The genetically distinct collagens

1985 • 124 citations

Cell detachment and metastasis

1983 • 123 citations

Collagen and Collagen-derived Fragments Are Chemotactic for Tumor Cells

1981 • 121 citations

Fibronectin and Other Structural Proteins

1981 • 116 citations

A comparison of the migration patterns of normal and malignant cells in two assay systems.

1978 • 113 citations

Changes in malignant phenotype of a human carcinoma conditioned by growth environment

1983 • 106 citations

Differential adhesion of tumor cells to capillary endothelial cells in vitro.

1984 • 106 citations

Tumor cell diversity and host responses in cancer metastasis—Part I—Properties of metastatic cells

1982 • 103 citations

Metastatic potential of murine fibrosarcoma cells is influenced by cell surface laminin

1984 • 96 citations

Laminin, Proteoglycan, Nidogen and Collagen IV: Structural Models and Molecular Interactions

1984 • 95 citations

Tumor cell attachment to the vascular endothelium and subsequent degradation of the subendothelial extracellular matrix

1982 • 92 citations

Tumor Metastasis Is Not Due to Adaptation of Cells to a New Organ Environment

1982 • 89 citations

The Internal Milieu of Tumors

2015 • 86 citations

An in vitro quantitative assay for tumor cell invasion.

1978 • 83 citations

Measurement of the Ability of Cells to Infiltrate Normal Tissues in vitro

1974 • 81 citations

Selection and characterization in culture of mammary tumor cells with distinctive growth properties in vivo.

1980 • 81 citations

Immunohistochemical study of embryonic chick heart invaded by malignant cells in three-dimensional culture.

1981 • 74 citations

Stimulation of haptotaxis and migration of tumor cells by serum spreading factor.

1985 • 68 citations

Detection of a cell-surface antigen correlated with organ-specific metastasis

1980 • 67 citations

Murine melanoma: a model for intracranial metastasis

1980 • 67 citations

Enhanced chemotaxis of tumor‐derived and virus‐transformed cells to fibronectin and fibroblast‐conditioned medium

1984 • 67 citations

Characterization of a laminin receptor from human breast carcinoma tissue

1984 • 67 citations

Interaction of metastatic tumor cells with bovine lens capsule basement membrane.

1984 • 65 citations

Organ specific metastasis with special reference to avian systems

1983 • 65 citations

A unique complement derived chemotactic factor for tumor cells.

1975 • 65 citations

Characteristics of the chemotactic response of neoplastic cells to a factor derived from the fifth component of complement.

1978 • 53 citations

Partial characterization of a bone-derived chemotactic factor for tumor cells.

1980 • 50 citations

Involvement of cell-cell adhesion molecules in liver colonization by metastatic murine lymphoma/lymphosarcoma variants

1984 • 46 citations

Patterns of Invasive Growth In Vitro. Human Decidua Graviditatis Confronted With Established Human Cell Lines and Primary Human Explants2

1976 • 44 citations

Observations on cancer metastasis in man

1982 • 44 citations

Clonal variation and functional correlation of organ‐specific metastasis and an organ‐specific metastasis‐associated antigen

1981 • 41 citations

Cell interactions in the metastatic process: some cell surface properties associated with successful blood-borne tumor spread.

1977 • 40 citations

Binding domain for laminin on type IV collagen

1985 • 39 citations

The effects of laminin on the growth and differentiation of embryonal carcinoma cells in defined media

1980 • 34 citations

Relationship between the C5 Peptides Chemotactic for Leukocytes and Tumor Cells

1976 • 30 citations

Invasion of Vascular Endothelial Cell Monolayers and Underlying Matrix by Metastatic Human Cancer Cells

1981 • 25 citations

Methods and models for studying tumor invasion

1982 • 19 citations

Melanoma cells growing in aggregates on a non-adhesive poly(HEMA) substrate exhibit polykaryocytosis but do not develop an increased metastatic capability

1984 • 15 citations

Metastatic Tumor Cell Attachment to Vascular Endothelial Cells and Destruction of Their Basal Lamina-Like Matrix

1983 • 8 citations