Anti‐metastatic and Anti‐invasive Effects of Polymeric Arg‐Gly‐Asp (RGD) Peptide, Poly(RGD), and Its Analogues

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

1984 • 3,580 citations

A rapid in vitro assay for quantitating the invasive potential of tumor cells.

1987 • 1,787 citations

Arg-Gly-Asp: A versatile cell recognition signal

1986 • 1,413 citations

Tumor invasion and the extracellular matrix.

1983 • 960 citations

Variants of the cell recognition site of fibronectin that retain attachment-promoting activity.

1984 • 685 citations

Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene.

1985 • 659 citations

Influence of stereochemistry of the sequence Arg-Gly-Asp-Xaa on binding specificity in cell adhesion.

1987 • 653 citations

A Synthetic Peptide from Fibronectin Inhibits Experimental Metastasis of Murine Melanoma Cells

1986 • 634 citations

Tumor cell instability, diversification, and progression to the metastatic phenotype: from oncogene to oncofetal expression.

1987 • 508 citations

Platelet—tumor‐cell interactions in mice. The role of platelets in the spread of malignant disease

1973 • 447 citations

Laminin and fibronectin promote the haptotactic migration of B16 mouse melanoma cells in vitro.

1984 • 314 citations

A cell surface receptor complex for collagen type I recognizes the Arg-Gly-Asp sequence.

1987 • 302 citations

Inhibition of platelet adhesion to fibronectin, fibrinogen, and von Willebrand factor substrates by a synthetic tetrapeptide derived from the cell-binding domain of fibronectin

1985 • 299 citations

?Seed and soil? revisited: mechanisms of site-specific metastasis

1982 • 276 citations

Migration by haptotaxis of a Schwann cell tumor line to the basement membrane glycoprotein laminin.

1983 • 259 citations

Basement Membrane and the Invasive Activity of Metastatic Tumor Cells

1986 • 209 citations

Correlation between spontaneous metastatic potential, platelet-aggregating activity of cell surface extracts, and cell surface sialylation in 10 metastatic-variant derivatives of a rat renal sarcoma cell line.

1980 • 192 citations

Investigation of the biological effects of anti-cell adhesive synthetic peptides that inhibit experimental metastasis of B16-F10 murine melanoma cells.

1988 • 175 citations

Arginyl-glycyl-aspartic acid sequences and fibrinogen binding to platelets

1987 • 165 citations

Inhibition of the metastasis of murine malignant melanoma by synthetic polymeric peptides containing core sequences of cell-adhesive molecules.

1989 • 125 citations

Type IV collagen-mediated melanoma cell adhesion and migration: involvement of multiple, distinct domains of the collagen molecule.

1989 • 96 citations

Inhibition of Tumor Cell Invasion by Ubenimex (Bestatin) in vitro

1989 • 88 citations

Antimetastatic effects of synthetic polypeptides containing repeated structures of the cell adhesive Arg-Gly-Asp (RGD) and Tyr-Ile-Gly-Ser-Arg (YIGSR) sequences

1989 • 83 citations

The inhibition of murine lung metastasis by synthetic polypeptides [poly(arg-gly-asp) and poly(tyr-ile-gly-ser-arg)] with a core sequence of cell adhesion molecules

1989 • 73 citations

Interaction of platelets and tumor cells

1982 • 50 citations

The Ernst W. Bertner Memorial Award lecture: the evolution of biological heterogeneity in metastatic neoplasms.

1983 • 49 citations

Inhibition of tumour cell adhesion by anti-metastatic polypeptide containing a repetitive Arg-Gly-Asp sequence

1989 • 9 citations