Interaction of the regulatory domains of the murine Cyp1a1 gene with two DNA-binding proteins in addition to the Ah receptor and the Ah receptor nuclear translocator (ARNT)

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity

1982 • 2,512 citations

P450 GENES: STRUCTURE, EVOLUTION, AND REGULATION

1987 • 1,559 citations

The molecular biology of cytochrome P450s.

1988 • 1,294 citations

Affinity purification of sequence-specific DNA binding proteins.

1986 • 1,255 citations

Isolation of a recombinant copy of the gene encoding C/EBP.

1988 • 1,003 citations

In Vivo Footprinting of a Muscle Specific Enhancer by Ligation Mediated PCR

1989 • 972 citations

Cloning of a Factor Required for Activity of the Ah (Dioxin) Receptor

1991 • 963 citations

Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor.

1992 • 830 citations

Identification of the Ah Receptor Nuclear Translocator Protein (Arnt) as a Component of the DNA Binding Form of the Ah Receptor

1992 • 769 citations

The DNA Binding Domain of the Rat Liver Nuclear Protein C/EBP Is Bipartite

1989 • 661 citations

Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.

1987 • 631 citations

In situ detection of sequence-specific DNA binding activity specified by a recombinant bacteriophage.

1988 • 535 citations

The Ah Locus: Genetic Differences in Toxicity, Cancer, Mutation, and Birth Defects

1989 • 458 citations

The DNA recognition site for the dioxin-Ah receptor complex. Nucleotide sequence and functional analysis.

1988 • 455 citations

Genetic and Molecular Aspects of 2,3,7,8-Tetra-Chlorodibenzo-P-Dioxin Action

1990 • 446 citations

Functional antagonism between c-Jun and MyoD proteins: A direct physical association

1992 • 424 citations

Genomic Sequencing and Methylation Analysis by Ligation Mediated PCR

1989 • 408 citations

cDNA cloning and structure of mouse putative Ah receptor

1992 • 406 citations

Purification of nuclear factor I by DNA recognition site affinity chromatography.

1986 • 331 citations

The Ah receptor and the mechanism of dioxin toxicity

1991 • 330 citations

Characterization of xenobiotic responsive elements upstream from the drug-metabolizing cytochrome P-450c gene: a similarity to glucocorticoid regulatory elements

1987 • 323 citations

Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer.

1988 • 268 citations

Fos and Jun repress transcriptional activation by myogenin and MyoD: the amino terminus of Jun can mediate repression.

1992 • 250 citations

The specific DNA binding activity of the dioxin receptor is modulated by the 90 kd heat shock protein.

1990 • 204 citations

A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to nucleus.

1988 • 198 citations

Ligand-dependent recruitment of the Arnt coregulator determines DNA recognition by the dioxin receptor.

1993 • 192 citations

Expression of liver phenotypes in cultured mouse hepatoma cells: Synthesis and secretion of serum albumin

1973 • 171 citations

Regulatory gene product of the Ah locus. Characterization of receptor mutants among mouse hepatoma clones.

1982 • 160 citations

Regulation of the mammalian cytochrome P1-450 (CYP1A1) gene

1989 • 148 citations

Control of cytochrome P1-450 gene expression: analysis of a dioxin-responsive enhancer system.

1986 • 146 citations

Regulatory DNA elements localized remotely upstream from the drug-metabolizing cytochrome P-450c gene

1986 • 128 citations

Regulation of Mouse CYP1A1 Gene Expression by Dioxin: Requirement of Two cis-Acting Elements during Induction

1989 • 126 citations

Mutations affecting the regulation of transcription of the cytochrome P1-450 gene in the mouse Hepa-1 cell line.

1985 • 124 citations

Dominant and recessive aryl hydrocarbon hydroxylase-deficient mutants of mouse hepatoma line, Hepa-1, and assignment of recessive mutants to three complementation groups

1983 • 124 citations

Protein-DNA interactions at a dioxin-responsive enhancer. Evidence that the transformed Ah receptor is heteromeric

1990 • 115 citations

Specific protein-DNA interactions at a xenobiotic-responsive element: copurification of dioxin receptor and DNA-binding activity.

1989 • 111 citations

Cytosolic and Nuclear Binding of 2,3,7,8‐Tetrachlorodibenzo‐p‐dioxin to the AhReceptor in Extra‐Hepatic Tissues of Rats and Mice

1982 • 103 citations

Cooperativity and specificity in the interactions between DNA and the glucocorticoid receptor DNA binding domain

1990 • 83 citations

Mechanism of dioxin action: Ah receptor-mediated increase in promoter accessibility in vivo.

1992 • 83 citations

Characterization of polyclonal antibodies to the Ah receptor prepared by immunization with a synthetic peptide hapten.

1991 • 74 citations

Regulation of mouse CYP1A1 gene expression by dioxin: requirement of two cis-acting elements during induction.

1989 • 72 citations

Nonresponsiveness of normal human fibroblasts to dioxin correlates with the presence of a constitutive xenobiotic response element-binding factor.

1993 • 71 citations

2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible, Ah receptor-mediated bending of enhancer DNA.

1990 • 70 citations

Analysis of two benzo[a]pyrene-resistant mutants of the mouse hepatoma Hepa-1 P(1)450 gene via cDNA expression in yeast.

1987 • 68 citations

Specific nuclear protein binding to a negative regulatory element on the human CYP1A1 gene

1993 • 62 citations

Multiple DNA-binding factors interact with overlapping specificities at the aryl hydrocarbon response element of the cytochrome P450IA1 gene.

1990 • 60 citations

Dioxin receptor and C/EBP regulate the function of the glutathione S-transferase Ya gene xenobiotic response element.

1993 • 60 citations

Characterization of multiple forms of the Ah receptor: recognition of a dioxin-responsive enhancer involves heteromer formation

1991 • 59 citations

Mechanism of dioxin action: receptor-enhancer interactions in intact cells

1993 • 59 citations

Activation of the dioxin and glucocorticoid receptors to a DNA binding state under cell-free conditions.

1990 • 51 citations

In Vivo Footprinting of a Muscle Specific Enhancer by Ligation Mediated PCR

1990 • 49 citations

Detection of the Ah receptor in rainbow trout: Use of 2-azido-3-[125I]iodo-7,8-dibromodibenzo-P-dioxmin in cell culture

1991 • 43 citations

Research on the Aryl Hydrocarbon (Dioxin) Receptor Is Primed to Take Off

1993 • 40 citations

Studies on the mechanism of action of halogenated aromatic hydrocarbons.

1985 • 35 citations

Measurements of the cytosolic Ah receptor among four strains of Drosophila melanogaster

1985 • 19 citations

Transcriptional derepression of the murine Cyp1a‐1 gene by mevinolin

1992 • 19 citations

Cooling Towers, Not "Smokestacks"

1990 • 4 citations