Identification of the Ah Receptor Nuclear Translocator Protein (Arnt) as a Component of the DNA Binding Form of the Ah Receptor

The myoD Gene Family: Nodal Point During Specification of the Muscle Cell Lineage

1991 • 1,564 citations

P450 GENES: STRUCTURE, EVOLUTION, AND REGULATION

1987 • 1,559 citations

Cloning of a Factor Required for Activity of the Ah (Dioxin) Receptor

1991 • 963 citations

Comparative Toxicology and Mechanism of Action of Polychlorinated Dibenzo-P-Dioxins and Dibenzofurans

1986 • 707 citations

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.

1989 • 643 citations

Association of the Ah receptor with the 90-kDa heat shock protein.

1988 • 511 citations

The DNA recognition site for the dioxin-Ah receptor complex. Nucleotide sequence and functional analysis.

1988 • 455 citations

Biochemistry, Molecular Biology, and Physiology of the Glucocorticoid Receptor*

1987 • 409 citations

Characterization of xenobiotic responsive elements upstream from the drug-metabolizing cytochrome P-450c gene: a similarity to glucocorticoid regulatory elements

1987 • 323 citations

Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer.

1988 • 268 citations

Association of the dioxin receptor with the Mr 90,000 heat shock protein: A structural kinship with the glucocorticoid receptor

1988 • 234 citations

Temperature-dependent cytosol-to-nucleus translocation of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in continuous cell culture lines.

1980 • 227 citations

The specific DNA binding activity of the dioxin receptor is modulated by the 90 kd heat shock protein.

1990 • 204 citations

Biochemical and genetic analysis of variant mouse hepatoma cells defective in the induction of benzo(a)pyrene-metabolizing enzyme activity.

1983 • 200 citations

A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to nucleus.

1988 • 198 citations

Single-step selection of clones of a mouse hepatoma line deficient in aryl hydrocarbon hydroxylase.

1979 • 191 citations

Structure and function of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Species difference in molecular properties of the receptors from mouse and rat hepatic cytosols.

1986 • 168 citations

Regulatory gene product of the Ah locus. Characterization of receptor mutants among mouse hepatoma clones.

1982 • 160 citations

Regulation of Mouse CYP1A1 Gene Expression by Dioxin: Requirement of Two cis-Acting Elements during Induction

1989 • 126 citations

Dominant and recessive aryl hydrocarbon hydroxylase-deficient mutants of mouse hepatoma line, Hepa-1, and assignment of recessive mutants to three complementation groups

1983 • 124 citations

Protein-DNA interactions at a dioxin-responsive enhancer. Evidence that the transformed Ah receptor is heteromeric

1990 • 115 citations

Specific protein-DNA interactions at a xenobiotic-responsive element: copurification of dioxin receptor and DNA-binding activity.

1989 • 111 citations

Characterization of multiple forms of the Ah receptor: comparison of species and tissues

1989 • 85 citations

Dioxin- and Ah receptor-dependent protein binding to xenobiotic responsive elements and G-rich DNA studied by in vivo footprinting.

1992 • 82 citations

The receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in the mouse hepatoma cell line Hepa 1c1c7. A comparison with the glucocorticoid receptor and the mouse and rat hepatic dioxin receptors.

1987 • 79 citations

Characterization of polyclonal antibodies to the Ah receptor prepared by immunization with a synthetic peptide hapten.

1991 • 74 citations

Dioxin Risks Revisited

1991 • 74 citations

Physicochemical characterization of the nuclear form of Ah receptor from mouse hepatoma cells exposed in culture to 2,3,7,8-tetrachlorodibenzo-p-dioxin

1988 • 71 citations

Multiple DNA-binding factors interact with overlapping specificities at the aryl hydrocarbon response element of the cytochrome P450IA1 gene.

1990 • 60 citations

Activation of the food-derived mutagen 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine by rabbit and human liver microsomes and purified forms of cytochrome P-450

1989 • 59 citations

Mutagenic activation of 2-amino-3-methylimidazo[4,5-f]quinoline by complementary DNA-expressed human liver P-450.

1990 • 57 citations

Hepatocarcinogenic heterocyclic aromatic amines that induce cytochrome P-448 isozymes, mainly cytochrome P-448H (P-450IA2), responsible for mutagenic activation of the carcinogens in rat liver

1989 • 56 citations

Evidence that benzo(a)pyrene-resistant, aryl hydrocarbon hydroxylase-deficient variants of mouse hepatoma line, Hepa-1, are mutational in origin

1981 • 52 citations

Purification of the Ah receptor from C57BL/6J mouse liver.

1988 • 52 citations

Role of the ligand in intracellular receptor function: receptor affinity determines activation in vitro of the latent dioxin receptor to a DNA-binding form.

1991 • 51 citations

Aryl hydrocarbon (Ah) receptor DNA-binding activity. Sequence specificity and Zn2+ requirement.

1990 • 49 citations

Ah receptor for 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin

1986 • 43 citations

Selective Mutagenic Activation by Cytochrome P3-450 of Carcinogenic Arylamines Found in Foods

1989 • 32 citations

A third genetic locus affecting the Ah (dioxin) receptor.

1988 • 30 citations

Flap Erupts Over Dioxin Meeting

1991 • 6 citations

US government orders new look at dioxin

1991 • 3 citations