Mechanism of dioxin action: Ah receptor-mediated increase in promoter accessibility in vivo.

2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity

1982 • 2,512 citations

Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes.

1980 • 1,277 citations

In Vivo Footprinting of a Muscle Specific Enhancer by Ligation Mediated PCR

1989 • 972 citations

Comparative Toxicology and Mechanism of Action of Polychlorinated Dibenzo-P-Dioxins and Dibenzofurans

1986 • 707 citations

Cancer Mortality in Workers Exposed to 2,3,7,8-Tetrachlorodibenzo-P-Dioxin

1991 • 542 citations

Steroid-dependent interaction of transcription factors with the inducible promoter of mouse mammary tumor virus in vivo

1987 • 448 citations

Genetic and Molecular Aspects of 2,3,7,8-Tetra-Chlorodibenzo-P-Dioxin Action

1990 • 446 citations

Nucleosome positioning modulates accessibility of regulatory proteins to the mouse mammary tumor virus promoter

1990 • 440 citations

Role of Nucleosomal Cores and Histone H1 in Regulation of Transcription by RNA Polymerase II

1991 • 379 citations

Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors

1987 • 356 citations

Protein-DNA Interactions at Recognition Sites for the Dioxin-Ah Receptor Complex

1989 • 215 citations

Glucocorticoids are required for establishment and maintenance of an alteration in chromatin structure: induction leads to a reversible disruption of nucleosomes over an enhancer.

1991 • 206 citations

Role of nucleosomal cores and histone H1 in regulation of transcription by RNA polymerase II

1991 • 204 citations

Biochemical and genetic analysis of variant mouse hepatoma cells defective in the induction of benzo(a)pyrene-metabolizing enzyme activity.

1983 • 200 citations

Constitutive and metal-inducible protein:DNA interactions at the mouse metallothionein I promoter examined by in vivo and in vitro footprinting.

1988 • 176 citations

In vivo footprinting of MHC class II genes: bare promoters in the bare lymphocyte syndrome

1991 • 175 citations

Autoregulation plus upstream positive and negative control regions associated with transcriptional activation of the mouse P₁450 gene

1985 • 174 citations

Regulation of cytochrome P1-450 gene transcription by 2,3,7, 8-tetrachlorodibenzo-p-dioxin in wild type and variant mouse hepatoma cells.

1984 • 166 citations

Control of cytochrome P1-450 gene expression: analysis of a dioxin-responsive enhancer system.

1986 • 146 citations

Regulatory DNA elements localized remotely upstream from the drug-metabolizing cytochrome P-450c gene

1986 • 128 citations

Organization and function of a dioxin-responsive enhancer.

1990 • 99 citations

Genomic footprinting of the yeast HSP82 promoter reveals marked distortion of the DNA helix and constitutive occupancy of heat shock and TATA elements

1990 • 99 citations

In vivo monitoring of a cAMP-stimulated DNA-binding activity.

1990 • 93 citations

The Potential Role of DNA Methylation in the Response to 2,3,7,8-Tetrachlorodibenzo-p-dioxin

1989 • 89 citations

Tissue-specific and steroid-dependent interaction of transcription factors with the oestrogen-inducible apoVLDL II promoter in vivo.

1988 • 86 citations

2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible, Ah receptor-mediated bending of enhancer DNA.

1990 • 70 citations

Functional analysis of the transcriptional promoter for the CYP1A1 gene.

1990 • 58 citations

A Laboratory Guide to Genomic Sequencing

1987 • 46 citations

2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible aryl hydrocarbon receptor-mediated change in CYP1A1 chromatin structure occurs independently of transcription.

1989 • 37 citations

Functional Analysis of the Transcriptional Promoter for the CYP1A1 Gene

1990 • 11 citations

2,3,7,8-Tetrachlorodibenzo-p-Dioxin-Inducible Aryl Hydrocarbon Receptor-Mediated Change in CYP1A1 Chromatin Structure Occurs Independently of Transcription

1989 • 6 citations