Melatonin stimulates brain glutathione peroxidase activity

Melatonin : a potent, endogenous hydroxyl radical scavenger

1993 • 1,673 citations

Importance of SE-glutathione peroxidase, catalase, and CU/ZN-SOD for cell survival against oxidative stress

1994 • 1,178 citations

Melatonin, hydroxyl radical‐mediated oxidative damage, and aging: A hypothesis

1993 • 493 citations

The significance of the metabolism of the neurohormone melatonin: Antioxidative protection and formation of bioactive substances

1993 • 434 citations

Melatonin—A Highly Potent Endogenous Radical Scavenger and Electron Donor: New Aspects of the Oxidation Chemistry of this Indole Accessed in vitroa

1994 • 356 citations

Melatonin As a Free Radical Scavenger: Implications for Aging and Age‐Related Diseases^a

1994 • 350 citations

The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo

1993 • 311 citations

Pineal control of aging: effect of melatonin and pineal grafting on aging mice.

1994 • 276 citations

Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole

1994 • 249 citations

Antioxidant capacity of melatonin: A novel action not requiring a receptor

1993 • 212 citations

Susceptibility of Glutathione Peroxidase and Glutathione Reductase to Oxidative Damage and the Protective Effect of Spin Trapping Agents

1994 • 182 citations

Concurrent determination of enzymatic activities and substrate concentrations in the melatonin synthetic pathway within the same rat pineal gland

1984 • 175 citations

Comparative study of the enzymatic defense systems against oxygen-derived free radicals: The key role of glutathione peroxidase

1987 • 158 citations

NGF restores decrease in catalase activity and increases superoxide dismutase and glutathione peroxidase activity in the brain of aged rats

1992 • 158 citations

An Automated Analysis of Glutathione Peroxidase, S-Transferase, and Reductase Activity in Animal Tissue

1983 • 136 citations

Biochemical Correlates of Longevity in Two Closely Related Rodent Species

1993 • 115 citations

Cu/Zn superoxide dismutase mRNA and enzyme activity, and susceptibility to lipid peroxidation, increases with aging in murine brains

1992 • 98 citations

Susceptibility of glutathione peroxidase to proteolysis after oxidative alteration by peroxides and hydroxyl radicals

1991 • 79 citations

Euthanasia by decapitation: Evidence that this technique produces prompt, painless unconsciousness in laboratory rodents

1992 • 63 citations

In vivo and in vitro effects of the pineal gland and melatonin on [Ca²⁺+ Mg²⁺]‐dependent ATPase in cardiac sarcolemma

1993 • 48 citations

Effects of a novel melatonin analog on circadian rhythms of body temperature and activity in young, middle-aged, and old rats

1993 • 46 citations

Transgenic Glutathione Peroxidase Mouse Models for Neuroprotection Studies^a

1994 • 38 citations

Prevention of microsomal production of hydroxyl radicals, but not lipid peroxidation, by the glutathione-glutathione peroxidase system

1986 • 36 citations

Melatonin prevents the suppression of cardiac Ca(2+)-stimulated ATPase activity induced by alloxan

1994 • 34 citations

Free radical scavenging by brain homogenate: Implication to free radical damage and antioxidant defense in brain

1994 • 20 citations

Protection by Dihydroergocryptine of Glutamate‐Induced Neurotoxicity

1993 • 14 citations

Enhancement of renal and hepatic glutathione metabolism by dimethylthiourea

1993 • 11 citations

Neurochemical aspects of aging in primates

1993 • 8 citations