The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo

Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*

1991 • 2,190 citations

Nuclease P1-mediated enhancement of sensitivity of ³²P-Postlabeling test for structurally diverse DNA adducts

1986 • 1,009 citations

Effects of the pineal hormone melatonin on the proliferation and morphological characteristics of human breast cancer cells (MCF-7) in culture.

1988 • 441 citations

Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles.

1978 • 432 citations

Structure-activity studies of the carcinogenicities in the mouse and rat of some naturally occurring and synthetic alkenylbenzene derivatives related to safrole and estragole.

1983 • 419 citations

Carcinogen-mediated oxidant formation and oxidative DNA damage

1992 • 387 citations

Human biomonitoring and the ³²P-postlabeling assay

1992 • 308 citations

Melatonin inhibition and pinealectomy enhancement of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in the rat.

1981 • 299 citations

The ageing pineal gland and its physiological consequences

1992 • 248 citations

³²P-Post-labelling analysis of DNA adducts formed in the livers of animals treated with safrole, estragole and other naturally-occurring alkenylbenzenes. II. Newborn male B6C3F₁ mice

1984 • 224 citations

Concurrent determination of enzymatic activities and substrate concentrations in the melatonin synthetic pathway within the same rat pineal gland

1984 • 175 citations

Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver.

1983 • 167 citations

The pineal gland and cancer

1988 • 155 citations

Age- and tissue-related DNA modifications in untreated rats: detection by ³²P-postlabeling assay and possible significance for spontaneous tumor induction and aging

1986 • 152 citations

The Pineal Control of Aging

1991 • 146 citations

32P-postlabeling assay in mice of transplacental DNA damage induced by the environmental carcinogens safrole, 4-aminobiphenyl, and benzo(a)pyrene.

1986 • 122 citations

Pineal melatonin inhibition of tumor promotion in theN-nitroso-N-methylurea model of mammary carcinogenesis: potential involvement of antiestrogenic mechanisms in vivo

1991 • 109 citations

Inhibitory Effects of the Natural Products Indole‐3‐carbinol and Sinigrin during Initiation and Promotion Phases of 4‐Nitroquinoline 1‐Oxide‐induced Rat Tongue Carcinogenesis

1992 • 102 citations

Prevention of cancer: Vegetables and plants

1989 • 77 citations

Effects of oltipraz, BHA, ADT and cabbage on glutathione metabolism, DNA damage and lipid peroxidation in old mice

1986 • 63 citations

Mechanisms of anti-carcinogenesis by indole-3-carbinol: effect on the distribution and metabolism of aflatoxin B₁ in rainbow trout

1986 • 57 citations

A comparison between different types of covalent DNA modifications (I-compounds, persistent carcinogen adducts and 5-methylcytosine) in regenerating rat liver

1988 • 54 citations

Association between diet and age-related DNA modifications (I-compounds) in rat liver and kidney.

1990 • 49 citations

Inhibition of Dunning Tumor Growth by Melatonin

1988 • 38 citations

Suppressive effect by melatonin on different phases of 9,10-dimethyl-1,2-benzanthracene (DMBA)-induced rat mammary gland carcinogenesis

1991 • 30 citations

Differences in induction of hepatic cytochrome p450 isozymes by mice in eight methylenedioxyphenyl compounds

1990 • 27 citations

The Ageing Pineal Gland and Its Physiological

1992 • 1 citations