PROGNOSTIC SIGNIFICANCE OF c‐erbB‐2 ONCOGENE IN AXILLARY NODE‐NEGATIVE BREAST CANCER

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Histological Grading and Prognosis in Breast Cancer

1957 • 2,897 citations

Relation of tumor size, lymph node status, and survival in 24,740 breast cancer cases

1989 • 2,245 citations

Presalvage prostate‐specific antigen (PSA) and PSA doubling time as predictors of biochemical failure of salvage cryotherapy in patients with locally recurrent prostate cancer after radiotherapy

2006 • 1,918 citations

A Randomized Clinical Trial Evaluating Tamoxifen in the Treatment of Patients with Node-Negative Breast Cancer Who Have Estrogen-Receptor–Positive Tumors

1989 • 1,471 citations

Diagnostic Histopathology of the Breast

1988 • 1,083 citations

c-erbB-2 Expression and Response to Adjuvant Therapy in Women with Node-Positive Early Breast Cancer

1994 • 981 citations

Mammographic screening and mortality from breast cancer: the Malmo mammographic screening trial.

1988 • 935 citations

Neu-Protein Overexpression in Breast Cancer

1988 • 860 citations

Prognostic importance of c-erbB-2 expression in breast cancer. International (Ludwig) Breast Cancer Study Group.

1992 • 855 citations

A prognostic index in primary breast cancer

1982 • 687 citations

Pathologic findings from the National Surgical Adjuvant Breast and Bowel Project: prognostic significance of erbB-2 protein overexpression in primary breast cancer.

1990 • 602 citations

Expression of c-erbB-2 oncoprotein: a prognostic indicator in human breast cancer.

1989 • 592 citations

Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading.

1988 • 570 citations

HER-2/neu in node-negative breast cancer: prognostic significance of overexpression influenced by the presence of in situ carcinoma.

1992 • 466 citations

Patterns of relapse and survival following radical mastectomy.Analysis of 716 consecutive patients

1978 • 465 citations

HER-2/neu amplification predicts poor survival in node-positive breast cancer.

1990 • 456 citations

Relative worth of estrogen or progesterone receptor and pathologic characteristics of differentiation as indicators of prognosis in node negative breast cancer patients: findings from National Surgical Adjuvant Breast and Bowel Project Protocol B-06.

1988 • 415 citations

A Randomized Clinical Trial Evaluating Sequential Methotrexate and Fluorouracil in the Treatment of Patients with Node-Negative Breast Cancer Who Have Estrogen-Receptor-Negative Tumors

1989 • 400 citations

Efficacy of Adjuvant Chemotherapy in High-Risk Node-Negative Breast Cancer

1989 • 359 citations

c-erbB-2 protein overexpression in breast cancer is a risk factor in patients with involved and uninvolved lymph nodes

1991 • 335 citations

Correlation between long-term survival in breast cancer patients and amplification of two putative oncogene-coamplification units: hst-1/int-2 and c-erbB-2/ear-1.

1989 • 321 citations

Prognostic significance of HER-2 oncoprotein expression in breast cancer: a 30-year follow-up.

1992 • 318 citations

Confirmation of a prognostic index in primary breast cancer

1987 • 311 citations

Follow-up study of HER-2/neu amplification in primary breast cancer.

1991 • 268 citations

Correlation between c-erbB-2 amplification and risk of recurrent disease in node-negative breast cancer.

1991 • 267 citations

c-erbB-2 oncoprotein expression in primary and advanced breast cancer

1991 • 245 citations

The long term prognostic significance of c-erbB-2 in primary breast cancer

1991 • 225 citations

Prognostic significance of HER-2/neu oncoprotein expression in node-positive breast cancer. The influence of the pattern of immunostaining and adjuvant therapy

1994 • 212 citations

An immunohistochemical evaluation of c-erbB-2 expression in human breast carcinoma

1988 • 206 citations

ADJUVANT THERAPY OF CANCER V

1988 • 194 citations

Prognostic significance of c-erbB-2 and estrogen receptor status in human breast cancer.

1991 • 187 citations

The relationship between c-erbB-2 expression, S-phase fraction and prognosis in breast cancer

1991 • 134 citations

p53 and c-erbB-2 Protein Expression in Breast Carcinomas: An Immunohistochemical Study Including Correlations with Receptor Status, Proliferation Markers, and Clinical Stage in Human Breast Cancer

1992 • 126 citations

c-erbB-2 amplification in node-negative human breast cancer.

1989 • 117 citations

Analysis of c-erbB-2 expression in breast carcinomas with clinical follow-up.

1989 • 115 citations

Human breast cancer: prognostic significance of the c-erbB-2 oncoprotein compared with epidermal growth factor receptor, DNA ploidy, and conventional pathologic features.

1992 • 103 citations

Pathologic findings from the national surgical adjuvant breast and bowel projects (NSABP) prognostic discriminants for 8-year survival for node-negative invasive breast cancer patients

1990 • 101 citations

Prognostic significance of c-erbB-2 expression in node negative breast cancer

1993 • 80 citations

Prognostic significance of co-expression of c-erbB-2 oncoprotein and epidermal growth factor receptor in breast cancer patients

1992 • 73 citations

c-erbB-2 protein expression in node negative breast cancer

1990 • 37 citations

Therapy of small breast cancer: A prospective study on 1036 patients with special emphasis on prognostic factors

1992 • 35 citations

Prognosis and treatment decisions in patients with breast cancer without axillary node involvement

1992 • 33 citations

Significance of c-erb5-2 amplification and DNA aneuploidy. Analysis in 78 patients with node-negative breast cancer

1992 • 29 citations

c-erbB-2 positive breast tumours behave more aggressively in the first years after diagnosis

1992 • 28 citations

Prognostic indicators in node-negative early stage breast cancer

1992 • 25 citations

Adjuvant systemic therapy for patients with node-negative tumors

1990 • 18 citations