Attenuation of haloperidol‐induced catalepsy by a 5‐HT_2C receptor antagonist

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values.

1989 • 1,313 citations

SB 242084, a Selective and Brain Penetrant 5-HT 2C Receptor Antagonist

1997 • 519 citations

Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile.

1996 • 342 citations

M100907, a Serotonin 5-HT2A Receptor Antagonist and Putative Antipsychotic, Blocks Dizocilpine-Induced Prepulse Inhibition Deficits in Sprague–Dawley and Wistar Rats

1999 • 203 citations

In vivo properties of SB 200646A, a 5‐HT_2C/2B receptor antagonist

1994 • 182 citations

Effect of drugs influencing central serotonergic mechanisms on haloperidol-induced catalepsy

1979 • 127 citations

Behavioral Effects of 5-HT2CReceptor Antagonism in the Substantia Nigra Zona Reticulata of the 6-Hydroxydopamine-Lesioned Rat Model of Parkinson's Disease

1998 • 80 citations

A role for the subthalamic nucleus in 5-HT2C-induced oral dyskinesia

1996 • 79 citations

Pre-clinical Pharmacology of Atypical Antipsychotic Drugs: A Selective Review

1996 • 74 citations

The Serotonin 5‐HT_2C Receptor Is a Prominent Serotonin Receptor in Basal Ganglia: Evidence from Functional Studies on Serotonin‐Mediated Phosphoinositide Hydrolysis

1997 • 67 citations

Serotonergic agents in the treatment of acute neuroleptic-induced akathisia

1997 • 31 citations

Cataleptogenic effect of subtype selective 5-HT receptor antagonists in the rat

1998 • 20 citations

5HT2-receptor antagonists can attenuate submaximal haloperidol-induced catalepsy in rats

1995 • 13 citations