Regulation of protein phosphatase-1

Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling

1995 • 2,907 citations

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

On target with a new mechanism for the regulation of protein phosphorylation

1993 • 901 citations

Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1

1995 • 850 citations

Beyond the Dopamine Receptor

1999 • 742 citations

Serine/threonine protein phosphatases

1995 • 635 citations

Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1

1997 • 625 citations

DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1

1984 • 610 citations

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

1999 • 557 citations

The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

1990 • 529 citations

Novel protein serine/threonine phosphatases: Variety is the spice of life

1997 • 503 citations

How do protein kinases recognize their substrates?

1996 • 470 citations

Separation and Characterization of Two Phosphorylase Phosphatase Inhibitors from Rabbit Skeletal Muscle

1976 • 439 citations

Crystal Structure of the Catalytic Subunit of Human Protein Phosphatase 1 and its Complex with Tungstate

1995 • 418 citations

Protein phosphatases: recent progress.

1991 • 391 citations

Myosin light chain phosphatase: subunit composition, interactions and regulation.

1998 • 391 citations

Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices

1990 • 356 citations

The Regulation of Glycogen Metaabolism

1978 • 297 citations

PTG, a Protein Phosphatase 1-Binding Protein with a Role in Glycogen Metabolism

1997 • 293 citations

The protein phosphatases involved in cellular regulation

1985 • 261 citations

[33] Classification of protein- serine/threonine phosphatases: identification and quantitation in cell extracts

1991 • 223 citations

Synergistic phosphorylation and activation of ATP-Mg-dependent phosphoprotein phosphatase by F A/GSK-3 and casein kinase II (PC0.7).

1984 • 212 citations

B cell receptor-associated protein α4 displays rapamycin-sensitive binding directly to the catalytic subunit of protein phosphatase 2A

1997 • 212 citations

Protein phosphatase type 1 in mammalian cell mitosis: chromosomal localization and involvement in mitotic exit.

1992 • 198 citations

Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II

1989 • 175 citations

Complete Primary Structure of Protein Phosphatase Inhibitor‐1 from Rabbit Skeletal Muscle

1982 • 163 citations

Amino acid sequence and expression of the hepatic glycogen‐binding (G_L‐subunit of protein phosphatase‐1

1995 • 161 citations

Multiple Structural Elements Define the Specificity of Recombinant Human Inhibitor-1 as a Protein Phosphatase-1 Inhibitor^,

1996 • 155 citations

The DARPP-32/protein phosphatase-1 cascade: a model for signal integration1Published on the World Wide Web on 22 January 1998.1

1998 • 154 citations

The yeast GLC7 gene required for glycogen accumulation encodes a type 1 protein phosphatase.

1991 • 153 citations

Isolation and Characterization of PNUTS, a Putative Protein Phosphatase 1 Nuclear Targeting Subunit

1998 • 153 citations

Identification of Protein‐Phosphatase‐1‐Binding Domains on the Glycogen and Myofibrillar Targetting Subunits

1996 • 150 citations

DARPP-32, a dopamine- and adenosine 3‘:5‘-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1.

1984 • 142 citations

Characterization of the Inhibition of Protein Phosphatase-1 by DARPP-32 and Inhibitor-2

1999 • 129 citations

A Protein Phosphatase-1-binding Motif Identified by the Panning of a Random Peptide Display Library

1997 • 128 citations

Regulation of protein phosphatase‐1_G from rabbit/skeletal muscle

1989 • 127 citations

Purification and characterisation of the insulin‐stimulated protein kinase from rabbit skeletal muscle; close similarity to S6 kinase II

1991 • 117 citations

Characterization of the interaction between DARPP-32 and protein phosphatase 1 (PP-1): DARPP-32 peptides antagonize the interaction of PP-1 with binding proteins

1997 • 117 citations

Molecular Cloning of NIPP-1, a Nuclear Inhibitor of Protein Phosphatase-1, Reveals Homology with Polypeptides Involved in RNA Processing

1995 • 115 citations

Role of Calcineurin and Protein Phosphatase‐2A in the Regulation of DARPP‐32 Dephosphorylation in Neostriatal Neurons

1999 • 114 citations

The hormonal control of glycogen metabolism: The amino acid sequence at the phosphorylation site of protein phosphatase inhibitor‐1

1977 • 107 citations

DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Primary structure and homology with protein phosphatase inhibitor-1.

1986 • 105 citations

Regulation of protein phosphatase‐1_G from rabbit skeletal muscle

1989 • 102 citations

Subunit Structure and Regulation of Protein Phosphatase-1 in Rat Liver Nuclei

1995 • 99 citations

Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity

1990 • 98 citations

Interactions of the Subunits of Smooth Muscle Myosin Phosphatase

1997 • 97 citations

The Mutant Type 1 Protein Phosphatase Encoded by glc7-1 from Saccharomyces cerevisiae Fails To Interact Productively with the GAC1-Encoded Regulatory Subunit

1994 • 96 citations

Dopamine- and cAMP-regulated phosphoprotein DARPP-32: phosphorylation of Ser-137 by casein kinase I inhibits dephosphorylation of Thr-34 by calcineurin.

1995 • 95 citations

Identification of inhibitor-2 as the ATP-mg-dependent protein phosphatase modulator.

1981 • 90 citations

Regulation of protein phosphatase 1 and 2A activities by insulin during myogenesis in rat skeletal muscle cells in culture.

1994 • 86 citations

Molecular mechanism of the synergistic phosphorylation of phosphatase inhibitor-2. Cloning, expression, and site-directed mutagenesis of inhibitor-2.

1994 • 84 citations

Phosphorylated synthetic peptides as tools for studying protein phosphatases

1994 • 83 citations

A New Isoform of Human Myosin Phosphatase Targeting/Regulatory Subunit (MYPT2): cDNA Cloning, Tissue Expression, and Chromosomal Mapping

1998 • 83 citations

Role of Protein Targeting to Glycogen (PTG) in the Regulation of Protein Phosphatase-1 Activity

1997 • 78 citations

Phosphorylation of DARPP-32, a Dopamine- and cAMP-regulated Phosphoprotein, by Casein Kinase I in Vitro and in Vivo

1995 • 77 citations

Regulation of ATP, Mg-Dependent Protein Phosphatases

1988 • 77 citations

Regulation of ATP—Mg-Dependent Protein Phosphatase

1984 • 76 citations

Inactivation of nuclear inhibitory polypeptides of protein phosphatase-1 (NIPP-1) by protein kinase A

1993 • 74 citations

A Kinetic Analysis of the Effects of Inhibitor-1 and Inhibitor-2 on the Activity of Protein Phosphatase-1

1983 • 74 citations

Targetting of protein phosphatase 1 to the sarcoplasmic reticulum of rabbit skeletal muscle by a protein that is very similar or identical to the G subunit that directs the enzyme to glycogen

1990 • 71 citations

Phosphorylation of the glycogen‐binding subunit of protein phosphatase‐1_G by cyclic‐AMP‐dependent protein kinase promotes translocation of the phosphatase from glycogen to cytosol in rabbit skeletal muscle

1986 • 67 citations

Mechanism of Inhibition of Protein Phosphatase 1 by DARPP-32: Studies with Recombinant DARPP-32 and Synthetic Peptides

1995 • 63 citations

The Regulation of Glycogen Synthase by Protein Phosphatase 1 in 3T3-L1 Adipocytes

1997 • 63 citations

Identification and Characterization of the Human HCG V Gene Product as a Novel Inhibitor of Protein Phosphatase-1

1998 • 62 citations

Isolation and characterisation of active fragments of protein phosphatase inhibitor‐1 from rabbit skeletal muscle

1982 • 62 citations

Differential localization of myosin and myosin phosphatase subunits in smooth muscle cells and migrating fibroblasts.

1997 • 61 citations

Distribution of Protein Phosphatase Inhibitor‐1 in Brain and Peripheral Tissues of Various Species: Comparison with DARPP‐32

1992 • 60 citations

Regulation of Myosin Phosphatase Through Phosphorylation of the Myosin-Binding Subunit in Platelet Activation

1997 • 59 citations

Identification of the sites on rabbit skeletal muscle protein phosphatase inhibitor-2 phosphorylated by casein kinase-II

1986 • 59 citations

The mutant type 1 protein phosphatase encoded by glc7-1 from Saccharomyces cerevisiae fails to interact productively with the GAC1-encoded regulatory subunit.

1994 • 55 citations

Properties and Phosphorylation Sites of Baculovirus-expressed Nuclear Inhibitor of Protein Phosphatase-1 (NIPP-1)

1997 • 52 citations

Interaction of Myosin Phosphatase Target Subunit 1 with the Catalytic Subunit of Type 1 Protein Phosphatase

1998 • 50 citations

Localization of the Gene Coding for Myosin Phosphatase, Target Subunit 1 (MYPT1) to Human Chromosome 12q15–q21

1997 • 49 citations

Analysis of the in vivo phosphorylation state of protein phosphatase inhibitor-2 from rabbit skeletal muscle by fast-atom bombardment mass spectrometry

1987 • 48 citations

Multisite Phosphorylation and the Nuclear Localization of Phosphatase Inhibitor 2-Green Fluorescent Protein Fusion Protein during S Phase of the Cell Growth Cycle

1997 • 42 citations

NIPP-1, a Nuclear Inhibitory Subunit of Protein Phosphatase-1, Has RNA-binding Properties

1997 • 40 citations

Phosphorylation of the glycogen-binding subunit of protein phosphatase-1_G in response to adrenalin

1988 • 40 citations

Protein phosphorylation and dephosphorylation in mammalian central nervous system

1993 • 35 citations

Fluorescence studies on the interaction of inhibitor 2 and okadaic acid with the catalytic subunit of type 1 phosphoprotein phosphatases

1991 • 35 citations

Dephosphorylation of Ser-137 in DARPP-32 by protein phosphatases 2A and 2C: different roles in vitro and in striatonigral neurons

1998 • 31 citations

Myosin Binding Subunit of Smooth Muscle Myosin Phosphatase at the Cell-Cell Adhesion Sites in MDCK Cells

1997 • 30 citations

Protein Phosphatase Type-1 and Glycogen Bind to a Domain in the Skeletal Muscle Regulatory Subunit Containing Conserved Hydrophobic Sequence Motifs

1996 • 28 citations

Purification and Characterization of a Smooth Muscle Myosin Light Chain Kinase-Phosphatase Complex

1997 • 27 citations

The Purification and Characterization of Protein Phosphatase Inhibitor-1 from Rabbit Skeletal Muscle

1978 • 24 citations

Phosphorylation of the Inhibitor-2 of Protein Phosphatase-1 by cdc2-Cyclin B and GSK3

1995 • 22 citations

Native cytosolic protein phosphatase‐1 (PP‐1S) containing modulator (inhibitor‐2) is an active enzyme

1994 • 21 citations

DARPP‐32 (dopamine and cAMP‐regulated phosphoprotein, M_r 32,000) is a membrane protein in the bovine parathyroid

1995 • 8 citations

Cell adhesion molecules and intracellular signalling: From fly to man

1995 • 6 citations