Immune complexes inhibit antimicrobial responses through interleukin-10 production. Effects in severe combined immunodeficient mice during Listeria infection.

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

1991 • 3,812 citations

Development of T _H 1 CD4 ⁺ T Cells Through IL-12 Produced by Listeria -Induced Macrophages

1993 • 3,140 citations

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

1989 • 2,771 citations

A severe combined immunodeficiency mutation in the mouse

1983 • 2,193 citations

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

1991 • 1,950 citations

IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells.

1991 • 1,880 citations

Interleukin-10

1993 • 1,820 citations

Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells.

1993 • 1,409 citations

Fc Receptors

1991 • 1,220 citations

Immunity to Intracellular Bacteria

1993 • 1,085 citations

Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.

1993 • 792 citations

Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1

1985 • 749 citations

Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection.

1985 • 555 citations

Role of T‐Cell Derived Cytokines in the Downregulation of Immune Responses in Parasitic and Retroviral Infection

1992 • 473 citations

Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors.

1989 • 385 citations

Diversity of Cytokine Synthesis and Function of Mouse CD4⁺ T Cells

1991 • 371 citations

Natural Immunity: A T‐Cell‐Independent Pathway of Macrophage Activation, Defined in the scid Mouse

1991 • 321 citations

Early gamma interferon production by natural killer cells is important in defense against murine listeriosis

1991 • 316 citations

Production of IL-10 by CD4+ T lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection.

1991 • 312 citations

Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma.

1994 • 305 citations

Monoclonal antibodies to murine gamma-interferon which differentially modulate macrophage activation and antiviral activity.

1985 • 286 citations

Tumor necrosis factor is involved in the T cell-independent pathway of macrophage activation in scid mice.

1989 • 275 citations

Infection with Schistosoma mansoni alters Th1/Th2 cytokine responses to a non-parasite antigen.

1992 • 256 citations

Isolation of monoclonal antibodies specific for IL-4, IL-5, IL-6, and a new Th2-specific cytokine (IL-10), cytokine synthesis inhibitory factor, by using a solid phase radioimmunoadsorbent assay.

1990 • 247 citations

A T cell-independent mechanism of macrophage activation by interferon-gamma.

1987 • 239 citations

Surface properties of bacillus Calmette-Guérin-activated mouse macrophages. Reduced expression of mannose-specific endocytosis, Fc receptors, and antigen F4/80 accompanies induction of Ia.

1981 • 232 citations

IL-10 stimulates monocyte Fc gamma R surface expression and cytotoxic activity. Distinct regulation of antibody-dependent cellular cytotoxicity by IFN-gamma, IL-4, and IL-10.

1992 • 220 citations

Regulation of gamma interferon production by natural killer cells in scid mice: roles of tumor necrosis factor and bacterial stimuli

1991 • 215 citations

The Role of Autoantibodies in Autoimmune Disease

1993 • 184 citations

Pathogen-induced Th1 phenotype development in CD4⁺ αβ-TCR transgenic T cells is macrophage dependent

1993 • 133 citations

Interleukin 1 participates in the development of anti-Listeria responses in normal and SCID mice.

1992 • 110 citations

Regulation of macrophage Ia expression in mice with severe combined immunodeficiency: induction of Ia expression by a T cell-independent mechanism.

1986 • 110 citations

EVIDENCE FOR CIRCULATING IMMUNE COMPLEXES IN LEPROMATOUS LEPROSY

1972 • 105 citations

Immunity to Intracellular Bacteria

1993 • 71 citations

The immunopathology of erythema nodosum leprosum: the role of extravascular complexes

1983 • 64 citations

Renal manifestations of leprosy: Glomerulonephritis, a complication of erythema nodosum leprosum *

1973 • 52 citations

Role of IL-10 on antigen-presenting cell function for schistosomal egg-specific monoclonal T helper cell responses in vitro and in vivo.

1993 • 52 citations

Presence of C1q-reactive immune complexes in patients with leprosy.

1972 • 50 citations

Immune complex effects on murine macrophages. I. Immune complexes suppress interferon-gamma induction of Ia expression.

1985 • 50 citations

Circulating and Tissue-Bound Immune Complex Formation in Murine Malaria

1979 • 47 citations

Adoptive transfer of modulation of granuloma formation and hepatosplenic disease in murine schistosomiasis japonica by serum from chronically infected animals.

1982 • 42 citations

Suppression of the immune response to Listeria monocytogenes. I. Immune complexes inhibit resistance.

1984 • 42 citations

Inhibition of macrophage tumoricidal activity by immune complexes and altered erythrocytes.

1983 • 33 citations

Circulating antigens and immune complexes in Schistosoma mansoni-infected rats. Characterization by radioimmunoprecipitation-PEG assay (RIPEGA).

1978 • 33 citations

Immune complex effects on murine macrophages. II. Immune complex effects on activated macrophages cytotoxicity, membrane IL 1, and antigen presentation.

1985 • 30 citations

IgG and IgE circulating immune complexes, total serum IgE and parasite related IgE in patients with mono- or mixed infection with Schistosoma mansoni and/or S. haematobium. Influence of therapy.

1983 • 28 citations

Immune regulation in murine schistosomiasis japonica: inhibition of in vitro antigen- and mitogen-induced cellular responses by splenocyte culture supernatants and by purified fractions from serum of chronically infected mice.

1982 • 28 citations

Inhibition of Natural Killer Cell Activity by Antigen‐Antibody Complexes

1986 • 26 citations

Suppression of immune response to Listeria monocytogenes: mechanism(s) of immune complex suppression

1985 • 25 citations

The Role of Autoantibodies in Autoimmune Disease

1993 • 9 citations

Serum-soluble malarial antigens and immune complex nephritis in Plasmodium berghei berghei infected mice.

1976 • 7 citations