The Role of Autoantibodies in Autoimmune Disease

Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion

1991 • 1,014 citations

A New Approach to the Classification of Idiopathic Inflammatory Myopathy

1991 • 959 citations

The "primary" antiphospholipid syndrome: major clinical and serological features.

1989 • 909 citations

Antiphospholipid Antibodies and the Antiphospholipid Syndrome in Systemic Lupus Erythematosus A Prospective Analysis of 500 Consecutive Patients

1989 • 637 citations

PATHOGENESIS OF THE GLOMERULONEPHRITIS OF NZB/W MICE

1968 • 622 citations

Association between Lupus Psychosis and Antiribosomal P Protein Antibodies

1987 • 597 citations

Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins

1982 • 531 citations

Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus.

1992 • 494 citations

Immunology and Clinical Importance of Antiphospholipid Antibodies

1991 • 490 citations

Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice

1991 • 485 citations

Induction of anti-phospholipid syndrome in naive mice with mouse lupus monoclonal and human polyclonal anti-cardiolipin antibodies.

1991 • 464 citations

Myositis autoantibody inhibits histidyl-tRNA synthetase: a model for autoimmunity

1983 • 402 citations

Human autoantibody to a novel protein of the nuclear coiled body: immunological characterization and cDNA cloning of p80-coilin.

1991 • 369 citations

DNA Hydrolyzing Autoantibodies

1992 • 363 citations

Ultraviolet light induces binding of antibodies to selected nuclear antigens on cultured human keratinocytes.

1984 • 334 citations

Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes.

1987 • 319 citations

Selective Expression of Purkinje-Cell Antigens in Tumor Tissue from Patients with Paraneoplastic Cerebellar Degeneration

1990 • 285 citations

Anti-DNA antibodies bind directly to renal antigens and induce kidney dysfunction in the isolated perfused rat kidney.

1989 • 265 citations

Antiphospholipid antibodies and cerebral ischemia in young people

1990 • 250 citations

Immune Mechanisms In Graves' Disease

1985 • 217 citations

64 000 Mr autoantibodies as predictors of insulin-dependent diabetes

1990 • 208 citations

Primary biliary cirrhosis: Paradigm or paradox for autoimmunity

1991 • 204 citations

Autoantibodies against alanyl-tRNA synthetase and tRNAAla coexist and are associated with myositis.

1986 • 196 citations

Autoantibodies to the ribosomal P proteins react with a plasma membrane-related target on human cells.

1992 • 188 citations

Structural requirement for autoreactivity on human pyruvate dehydrogenase-E2, the major autoantigen of primary biliary cirrhosis. Implication for a conformational autoepitope.

1990 • 173 citations

Invited review: Motor neuropathies, motor neuron disorders, and antiglycolipid antibodies

1991 • 171 citations

Antibodies to glycosphingolipids in patients with multiple sclerosis and SLE.

1984 • 169 citations

Anti—Ro/SS‐a Antibodies in the Pathophysiology of Congenital Heart Block in Neonatal Lupus Syndrome, An Experimental Model

1992 • 150 citations

Transfer of human systemic lupus erythematosus in severe combined immunodeficient (SCID) mice.

1990 • 149 citations

Autoantibodies to a 64-Kilodalton Islet Cell Protein Precede the Onset of Spontaneous Diabetes in the BB Rat

1984 • 147 citations

Viruses in idiopathic inflammatory myopathies: absence of candidate viral genomes in muscle

1992 • 143 citations

The role of an autoantigen, histidyl-tRNA synthetase, in the induction and maintenance of autoimmunity.

1990 • 139 citations

Autoimmunity and Autoimmune Diseases

1989 • 137 citations

Autoantibodies against ribosomal proteins found with high frequency in patients with systemic lupus erythematosus with active disease.

1991 • 131 citations

Origin and regulation of a disease-specific autoantibody response. Antigenic epitopes, spectrotype stability, and isotype restriction of anti-Jo-1 autoantibodies.

1990 • 122 citations

Autoantibodies to GABAergic neurons and response to plasmapheresis in stiff‐man syndrome

1991 • 121 citations

Gynecologic Cancer in Patients With Subacute Cerebellar Degeneration Predicted by Anti-Purkinje Cell Antibodies and Limited in Metastatic Volume

1990 • 119 citations

Autoantibody to th ribonucleoprotein (nucleolar 7–2 rna protein particle) in patients with systemic sclerosis

1990 • 109 citations

Estradiol enhances binding to cultured human keratinocytes of antibodies specific for SS-A/Ro and SS-B/La. Another possible mechanism for estradiol influence of lupus erythematosus.

1988 • 107 citations

Cardiac myosin-induced myocarditis. Heart autoantibodies are not involved in the induction of the disease.

1990 • 103 citations

The antiphospholipid syndrome: a syndrome in evolution.

1992 • 100 citations

Anti-DNA antibodies and lupus nephritis: the complexity of crossreactivity

1990 • 99 citations

Cross-reactivity of monoclonal anti-DNA antibodies with heparan sulfate is mediated via bound DNA/histone complexes

1990 • 92 citations

A monoclonal anti-double-stranded DNA autoantibody binds to a 94-kDa cell-surface protein on various cell types via nucleosomes or a DNA-histone complex.

1989 • 91 citations

Antibodies to native DMA and serum complement (C3) levels

1983 • 89 citations

TEN-YEAR FOLLOW-UP STUDY OF ISLET-CELL ANTIBODIES AND CHILDHOOD DIABETES MELLITUS

1989 • 89 citations

The Pathogenic Role of Antineutrophil Cytoplasmic Autoantibodies

1991 • 81 citations

Human peripheral blood monocytes display surface antigens recognized by monoclonal antinuclear antibodies.

1985 • 79 citations

Insulin autoantibodies: Their role in the pathogenesis of IDDM

1987 • 77 citations

Importance of the immune response to the Ro/La particle in the development of congenital heart block and neonatal lupus erythematosus

1991 • 74 citations

DNA receptor dysfunction in systemic lupus erythematosus and kindred disorders. Induction by anti-DNA antibodies, antihistone antibodies, and antireceptor antibodies.

1987 • 74 citations

Cross-reactivity distinguishes serum and nephritogenic anti-DNA antibodies in human lupus from their natural counterparts in normal serum

1990 • 67 citations

Cleavage of vasoactive intestinal peptide at multiple sites by autoantibodies

1991 • 60 citations

Enzymatic acylation of histidine to mengovirus RNA

1974 • 60 citations

Intravenous γ-globulin in myasthenia gravis: Interaction with anti-acetylcholine receptor autoantibodies

1991 • 57 citations

Molecular basis of mitochondrial autoreactivity in primary biliary cirrhosis

1989 • 56 citations

Antiphospholipid Antibodies and Recurrent Pregnancy Loss

1991 • 55 citations

Anti-acetylcholine receptor antibodies decrease after thymectomy in patients with myasthenia gravis. Clinical correlations

1991 • 55 citations

Clinical correlations of Anti‐Gm1 antibodies in amyotrophic lateral sclerosis and neuropathies

1991 • 52 citations

Myasthenia Gravis: Prototype of the Antireceptor Autoimmune Diseases

1990 • 47 citations

ANTI-TYPE II COLLAGEN ANTIBODY IN NATURALLY OCCURRING CANINE JOINT DISEASES

1989 • 46 citations

Anti-Myosin Humoral Immune Response Following Cardiac Injury

1989 • 43 citations

Independent analysis of the 16/6 idiotype lupus model. A role for an environmental factor?

1991 • 41 citations

Lupus antiribosomal P antisera contain antibodies to a small fragment of 28S rRNA located in the proposed ribosomal GTPase center.

1991 • 41 citations

Viral and host genetic factors influence encephalomyocarditis virus—induced polymyositis in adult mice

1987 • 40 citations

The Role of Cationic Proteins in the Pathogenesis of Immune Complex Glomerulonephritis

1990 • 39 citations

Anti-acetylcholine receptor antibodies in neonatal myasthenia gravis: Heterogeneity and pathogenic significance

1991 • 36 citations

Cellular and subcellular localization of an Mr 64,000 protein autoantigen in insulin-dependent diabetes.

1990 • 36 citations

Diagnostic value of anti-neuronal antibodies for paraneoplastic disorders of the nervous system.

1990 • 31 citations

Disease associations and pathogenic role of antineutrophil cytoplasmic autoantibodies in vasculitis.

1992 • 31 citations

Electrophysiologic studies in the Guillain–Barré syndrome: Effects of plasma exchange and antibody rebound

1992 • 31 citations

Sulfated glycolipids are the platelet autoantigens for human platelet-binding monoclonal anti-DNA autoantibodies

1991 • 30 citations

Analysis of autoantibody production in SCID-systemic lupus erythematosus (SLE) chimeras

1992 • 28 citations

A role for DNA in anti-DNA antibodies binding to endothelial cells

1991 • 24 citations

Anti-P autoantibody production requires P1/P2 as immunogens but is not driven by exogenous self-antigen in MRL mice.

1991 • 24 citations

Autoimmunity of Diabetes

1991 • 13 citations

Shifts of anti-Sm-specific antibodies in patients with systemic lupus erythematosus: Analysis by counter-immunoelectrophoresis, immunoblotting and RNA-immunoprecipitation

1991 • 12 citations

Clinical and Laboratory Evaluation of Hemocarboadsorption in Autoimmune Bullous Dermatoses

1990 • 8 citations

Plasma exchange in Guillain-Barré syndrome: effect on anti-peripheral nerve myelin antibodies

2009 • 8 citations

In vivo studies of antibody dependent acantholysis.

1989 • 7 citations

In vitro studies of acantholysis of keratinocytes induced by pemphigus antibody.

1989 • 6 citations

Anca: A Class of Vasculitis-Associated Autoantibodies Against Myeloid Granule Proteins: Clinical and Laboratory Aspects and Possible Pathogenetic Implications

1991 • 6 citations

Recent advances in the pathogenesis of systemic lupus erythematosus.

1990 • 5 citations