β2-Adrenergic Receptor/Cyclic Adenosine Monophosphate (cAMP) Leads to JNK Activation through Rho Family Small GTPases

Rho GTPases and signaling networks

1997 • 2,380 citations

Regulation of the Cytoskeleton and Cell Adhesion by the Rho Family GTPases in Mammalian Cells

1999 • 1,015 citations

The Pathways Connecting G Protein-coupled Receptors to the Nucleus through Divergent Mitogen-activated Protein Kinase Cascades

1998 • 819 citations

Ras and Rho GTPases

2000 • 779 citations

Bidirectional signaling between the cytoskeleton and integrins

1999 • 765 citations

Characterization of Rac and Cdc42 Activation in Chemoattractant-stimulated Human Neutrophils Using a Novel Assay for Active GTPases

1999 • 765 citations

Regulation of tyrosine kinase cascades by G-protein-coupled receptors

1999 • 688 citations

Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase

1998 • 542 citations

The Small GTPase Rho: Cellular Functions and Signal Transduction

1996 • 404 citations

The Role of Rho in G Protein-Coupled Receptor Signal Transduction

2000 • 345 citations

Adrenergic Receptors as Models for G Protein-Coupled Receptors

1992 • 340 citations

Down-regulation of beta-adrenergic receptors: agonist-induced reduction in receptor mRNA levels.

1988 • 268 citations

Signaling from G Protein-coupled Receptors to c-Jun Kinase Involves βγ Subunits of Heterotrimeric G Proteins Acting on a Ras and Rac1-dependent Pathway

1996 • 246 citations

Dual Effect of β-Adrenergic Receptors on Mitogen-activated Protein Kinase

1995 • 223 citations

Glucosylation and ADP Ribosylation of Rho Proteins: Effects on Nucleotide Binding, GTPase Activity, and Effector Coupling

1998 • 211 citations

Transforming G Protein-coupled Receptors Potently Activate JNK (SAPK)

1995 • 211 citations

Heterotrimeric G-protein βγ-dimers in growth and differentiation

2001 • 194 citations

Mutagenesis of the beta2-Adrenergic Receptor: How Structure Elucidates Function

1992 • 192 citations

Accumulation of GTP-bound RhoA during Cytokinesis and a Critical Role of ECT2 in This Accumulation

2000 • 163 citations

Activation of p38 Mitogen-activated Protein Kinase by Signaling through G Protein-coupled Receptors

1997 • 154 citations

Secondary and Tertiary Structure Changes of Reconstituted P-glycoprotein

1996 • 141 citations

The Seven-transmembrane-spanning Receptors for Endothelin and Thrombin Cause Proliferation of Airway Smooth Muscle Cells and Activation of the Extracellular Regulated Kinase and c-Jun NH2-terminal Kinase Groups of Mitogen-activated Protein Kinases

1996 • 111 citations

c-Jun N-terminal Kinase but Not Mitogen-activated Protein Kinase Is Sensitive to cAMP Inhibition in T Lymphocytes

1995 • 106 citations

D₁Dopamine Receptor Agonists Mediate Activation of p38 Mitogen-Activated Protein Kinase and c-Jun Amino-Terminal Kinase by a Protein Kinase A-Dependent Mechanism in SK-N-MC Human Neuroblastoma Cells

1998 • 85 citations

Down-regulation of β-adrenergic receptor : agonist-induced reduction in mRNA levels

1988 • 82 citations

Differential calcium dependence in the activation of c-Jun kinase and mitogen-activated protein kinase by muscarinic acetylcholine receptors in rat 1a cells

1995 • 64 citations

Activation of the Guanine Nucleotide Exchange Factor Dbl Following ACK1-Dependent Tyrosine Phosphorylation

2000 • 61 citations

Differential Regulation of Mitogen-activated Protein Kinase Kinase 4 (MKK4) and 7 (MKK7) by Signaling from G Protein βγ Subunit in Human Embryonal Kidney 293 Cells

1999 • 60 citations

Cyclic AMP Inhibition of Thrombin-induced Growth in Vascular Smooth Muscle Cells Correlates with Decreased JNK1 Activity and c-Jun Expression

1996 • 58 citations

Cyclic AMP and Protein Kinase A Stimulate Cdc42: Role of A₂Adenosine Receptors in Human Mast Cells

2000 • 56 citations

Gi-dependent Activation of c-Jun N-terminal Kinase in Human Embryonal Kidney 293 Cells

2000 • 54 citations

Cyclic AMP distinguishes between two functions of acidic FGF in a rat bladder carcinoma cell line.

1993 • 47 citations

Interplay between Ras‐related and heterotrimeric GTP binding proteins: lifestyles of the BIG and little ¹

1996 • 35 citations

Characteristics of an Adenylate Cyclase Coupled β-Adrenergic Receptor in a Smooth Muscle Tumor Cell Line

1983 • 22 citations

Functional Involvement of mSos in Interleukin-3 and Thrombin Stimulation of the Ras, Mitogen-Activated Protein Kinase Pathway in BaF3 Murine Hematopoietic Cells

1998 • 13 citations