Cell Distributions and Functions of Toll-like Receptor 4 Studied by Fluorescent Gene Constructs

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1998 • 7,541 citations

Toll-Like Receptors

2003 • 6,127 citations

THE GREEN FLUORESCENT PROTEIN

1998 • 5,991 citations

Innate Immunity: The Virtues of a Nonclonal System of Recognition

1997 • 2,397 citations

MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4

1999 • 2,188 citations

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens

1999 • 1,381 citations

The Pathogenesis of Sepsis

1991 • 1,376 citations

The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome.

1989 • 1,183 citations

Studying protein dynamics in living cells

2001 • 1,174 citations

Recognition of pathogen-associated molecular patterns by TLR family

2003 • 1,124 citations

ASSOCIATION BETWEEN TUMOUR NECROSIS FACTOR IN SERUM AND FATAL OUTCOME IN PATIENTS WITH MENINGOCOCCAL DISEASE

1987 • 1,108 citations

Essential role of MD-2 in LPS responsiveness and TLR4 distribution

2002 • 1,028 citations

Soluble CD14 participates in the response of cells to lipopolysaccharide.

1992 • 695 citations

Lipopolysaccharide Rapidly Traffics to and from the Golgi Apparatus with the Toll-like Receptor 4-MD-2-CD14 Complex in a Process That Is Distinct from the Initiation of Signal Transduction

2002 • 452 citations

Toll-like Receptor 4 Resides in the Golgi Apparatus and Colocalizes with Internalized Lipopolysaccharide in Intestinal Epithelial Cells

2002 • 414 citations

Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line

2001 • 300 citations

Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor.

1990 • 263 citations

Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to Toll-like receptor 4

2001 • 234 citations

CD14-Dependent Internalization of Bacterial Lipopolysaccharide (LPS) Is Strongly Influenced by LPS Aggregation But Not by Cellular Responses to LPS

1998 • 136 citations

Transport of Bacterial Lipopolysaccharide to the Golgi Apparatus

1999 • 123 citations

Bacterial Lipopolysaccharide Can Enter Monocytes Via Two CD14-Dependent Pathways

1998 • 86 citations

Internalization of Monomeric Lipopolysaccharide Occurs after Transfer Out of Cell Surface Cd14

1999 • 78 citations

Innate Immune Recognition of Bacterial Lipopolysaccharide: Dependence on Interactions with Membrane Lipids and Endocytic Movement

1998 • 78 citations

Lipopolysaccharide Internalization Activates Endotoxin-Dependent Signal Transduction in Cardiomyocytes

2001 • 47 citations

Interaction of FK506-binding protein 13 with brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1): Effects of FK506

2003 • 37 citations

Influence of CD 14, LBP and BPI in the Monocyte Response to LPS of Different Polysaccharide Chain Length

1995 • 26 citations

The secretory membrane system studied in real-time

2001 • 24 citations

Endotoxin-mimetic effect of antibodies against Toll-like receptor 4

2000 • 18 citations