Transport of Bacterial Lipopolysaccharide to the Golgi Apparatus

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1998 • 7,541 citations

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

1997 • 5,522 citations

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

1990 • 4,041 citations

The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor

1997 • 3,702 citations

Inflammation. Basic principles and clinical correlates

1989 • 2,424 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

1989 • 1,685 citations

Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 (Tlr4)

1999 • 1,570 citations

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

1998 • 1,218 citations

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

1993 • 1,197 citations

Human Toll-like Receptor 2 Confers Responsiveness to Bacterial Lipopolysaccharide

1998 • 778 citations

Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14.

1994 • 747 citations

The effects of bacterial endotoxins on host mediation systems. A review.

1978 • 648 citations

Inflammation: Basic Principles and Clinical Correlates

2000 • 616 citations

Recognition and plasma clearance of endotoxin by scavenger receptors

1991 • 529 citations

Sorting of sphingolipids in epithelial (Madin-Darby canine kidney) cells.

1987 • 443 citations

A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B.

1995 • 402 citations

Effects of cytokines on mycobacterial phagosome maturation

1998 • 349 citations

A Vital Stain for the Golgi Apparatus

1985 • 344 citations

E5531, a Pure Endotoxin Antagonist of High Potency

1995 • 322 citations

Endocytosis, intracellular transport, and cytotoxic action of Shiga toxin and ricin

1996 • 321 citations

Imaging the intracellular trafficking and state of the AB5 quaternary structure of cholera toxin.

1996 • 286 citations

Detoxification of Bacterial Lipopolysaccharides (Endotoxins) by a Human Neutrophil Enzyme

1986 • 278 citations

The unfolded protein response: an intracellular signalling pathway with many surprising features

1998 • 274 citations

Lipopolysaccharide (LPS) partial structures inhibit responses to LPS in a human macrophage cell line without inhibiting LPS uptake by a CD14-mediated pathway.

1992 • 273 citations

Soluble CD14 acts as a shuttle in the neutralization of lipopolysaccharide (LPS) by LPS-binding protein and reconstituted high density lipoprotein.

1995 • 268 citations

Lipopolysaccharide (LPS) Signal Transduction and Clearance

1995 • 260 citations

Quantification of low density lipoprotein and transferrin endocytic sorting in HEp2 cells using confocal microscopy

1994 • 212 citations

Stimulation of macrophages and neutrophils by complexes of lipopolysaccharide and soluble CD14.

1996 • 207 citations

Sphingomyelinase Treatment Induces ATP-independent Endocytosis

1998 • 204 citations

Catalytic Properties of Lipopolysaccharide (LPS) Binding Protein

1996 • 198 citations

Specific antimononuclear phagocyte monoclonal antibodies. Application to the purification of dendritic cells and the tissue localization of macrophages.

1983 • 197 citations

Uptake by liver cells of endotoxin following its intravenous injection.

1981 • 187 citations

An Ordered Inheritance Strategy for the Golgi Apparatus: Visualization of Mitotic Disassembly Reveals a Role for the Mitotic Spindle

1998 • 183 citations

Two functional domains in the phagocyte membrane glycoprotein Mo1 identified with monoclonal antibodies.

1986 • 174 citations

Adhesomes: specific granules containing receptors for laminin, C3bi/fibrinogen, fibronectin, and vitronectin in human polymorphonuclear leukocytes and monocytes.

1989 • 157 citations

Association between protective efficacy of anti-lipopolysaccharide (LPS) antibodies and suppression of LPS-induced tumor necrosis factor alpha and interleukin 6. Comparison of O side chain-specific antibodies with core LPS antibodies.

1990 • 150 citations

Monocytes can phagocytose Gram-negative bacteria by a CD14-dependent mechanism.

1996 • 144 citations

CD14-Dependent Internalization of Bacterial Lipopolysaccharide (LPS) Is Strongly Influenced by LPS Aggregation But Not by Cellular Responses to LPS

1998 • 136 citations

Surface functions during mitosis. II. Quantitation of pinocytosis and kinetic characterization of the mitotic cycle with a new fluorescence technique.

1980 • 136 citations

A series of fluorescent N-acylsphingosines: synthesis, physical properties, and studies in cultured cells

1988 • 124 citations

Structural Analysis of Differentiation Antigens Mol and Mo2 On Human Monocytes

1982 • 118 citations

Soluble CD14 Truncated at Amino Acid 152 Binds Lipopolysaccharide (LPS) and Enables Cellular Response to LPS

1995 • 86 citations

Bacterial Lipopolysaccharide Can Enter Monocytes Via Two CD14-Dependent Pathways

1998 • 86 citations

The Golgi and Endoplasmic Reticulum Remain Independent during Mitosis in HeLa Cells

1998 • 84 citations

Uptake and deacylation of bacterial lipopolysaccharides by macrophages from normal and endotoxin-hyporesponsive mice

1985 • 83 citations

Potential role of membrane internalization and vesicle fusion in adhesion of neutrophils in response to lipopolysaccharide and TNF.

1996 • 82 citations

Innate Immune Recognition of Bacterial Lipopolysaccharide: Dependence on Interactions with Membrane Lipids and Endocytic Movement

1998 • 78 citations

Internalization of Monomeric Lipopolysaccharide Occurs after Transfer Out of Cell Surface Cd14

1999 • 78 citations

DiOC₆(3): a Useful Dye for Staining the Endoplasmic Reticulum

1997 • 77 citations

pH-independent retrograde targeting of glycolipids to the Golgi complex

1998 • 74 citations

Mice Genetically Hyporesponsive to Lipopolysaccharide (LPS) Exhibit a Defect in Endocytic Uptake of LPS and Ceramide

1997 • 64 citations

Endoplasmicreticulum-induced signal transduction and gene expression

1997 • 64 citations

Fluorescent conjugates of brefeldin A selectively stain the endoplasmic reticulum and Golgi complex of living cells.

1995 • 47 citations

Ultrastructural and Immunocytochemical Study of the Uptake and Distribution of Bacterial Lipopolysaccharide in Human Monocytes

1990 • 46 citations

Sensitive responses of leukocytes to lipopolysaccharide require a protein distinct from CD14 at the cell surface.

1997 • 40 citations

Uptake, distribution and fate of bacterial lipopolysaccharides in monocytes and macrophages: An ultrastructural and functional correlation

1992 • 32 citations

Activation of murine lymphocytes by lipopolysaccharide incorporated in fusogenic, reconstituted influenza virus envelopes (virosomes).

1996 • 24 citations

Uptake and subcellular distribution of Escherichia coli lipopolysaccharide by isolated rat type II pneumocytes.

1991 • 20 citations

Interaction of lectins with proteins of the endoplasmic reticulum and golgi system of rat liver

1979 • 12 citations