Peripherin/rds and rom-1: Molecular properties and role in photoreceptor cell degeneration

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Cyclic GMP Cascade of Vision

1986 • 1,168 citations

A point mutation of the rhodopsin gene in one form of retinitis pigmentosa

1990 • 1,032 citations

Molecular Genetics of Inherited Variation in Human Color Vision

1986 • 777 citations

The structure of bovine rhodopsin

1983 • 513 citations

Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa.

1991 • 492 citations

Mutations within the Rhodopsin Gene in Patients with Autosomal Dominant Retinitis Pigmentosa

1990 • 478 citations

Transcending the impenetrable: How proteins come to terms with membranes

1988 • 471 citations

Mutations in the human retinal degeneration slow gene in autosomal dominant retinitis pigmentosa

1991 • 460 citations

Rhodopsin mutations in autosomal dominant retinitis pigmentosa.

1991 • 455 citations

Transgenic mice with a rhodopsin mutation (Pro23His): A mouse model of autosomal dominant retinitis pigmentosa

1992 • 454 citations

Mutations in the human retinal degeneration slow (RDS) gene can cause either retinitis pigmentosa or macular dystrophy

1993 • 427 citations

A Null mutation in the rhodopsin gene causes rod photoreceptor dysfunction and autosomal recessive retinitis pigmentosa

1992 • 417 citations

Two adjacent cysteine residues in the C‐terminal cytoplasmic fragment of bovine rhodopsin are palmitylated

1988 • 409 citations

Identification of a photoreceptor-specific mRNA encoded by the gene responsible for retinal degeneration slow (rds)

1989 • 399 citations

Disc morphogenesis in vertebrate photoreceptors

1980 • 394 citations

A three-base-pair deletion in the peripherin–RDS gene in one form of retinitis pigmentosa

1991 • 381 citations

The retinal degeneration slow (rds) gene product is a photoreceptor disc membrane-associated glycoprotein

1991 • 322 citations

Molecular mechanism of visual transduction

1989 • 312 citations

Peripherin. A rim-specific membrane protein of rod outer segment discs.

1987 • 300 citations

Localization of peripherin/rds in the disk membranes of cone and rod photoreceptors: relationship to disk membrane morphogenesis and retinal degeneration.

1992 • 297 citations

Native disulphide bond formation in protein biosynthesis: evidence for the role of protein disulphide isomerase

1984 • 293 citations

Photoreceptor peripherin is the normal product of the gene responsible for retinal degeneration in the rds mouse.

1991 • 284 citations

Butterfly–shaped pigment dystrophy of the fovea caused by a point mutation in codon 167 of the RDS gene

1993 • 272 citations

THE MOLECULAR MECHANISM OF VISUAL EXCITATION AND ITS RELATION TO THE STRUCTURE AND COMPOSITION OF THE ROD OUTER SEGMENT

1987 • 264 citations

Cloning of the CDNA for a novel photoreceptor membrane protein (rom-1) identifies a disk rim protein family implicated in human retinopathies

1992 • 254 citations

Fatty Acylation of Proteins

1988 • 253 citations

Autosomal dominant retinitis pigmentosa (ADRP): Localization of an ADRP gene to the long arm of chromosome 3

1989 • 241 citations

Immunocytochemical localization of a large intrinsic membrane protein to the incisures and margins of frog rod outer segment disks.

1978 • 238 citations

Development and degeneration of retina in rds mutant mice: Light microscopy

1980 • 238 citations

Differential immunogold-dextran labeling of bovine and frog rod and cone cells using monoclonal antibodies against bovine rhodopsin

1986 • 224 citations

A null mutation in the human peripherin/RDS gene in a family with autosomal dominant retinitis punctata albescens

1993 • 204 citations

A New H‐2‐Linked Mutation, rds, Causing Retinal Degeneration in the Mouse

1978 • 192 citations

On the Molecular Genetics of Retinitis Pigmentosa

1992 • 189 citations

Absence of receptor outer segments in the retina of rds mutant mice

1981 • 182 citations

Differences in the protein composition of bovine retinal rod outer segment disk and plasma membranes isolated by a ricin-gold-dextran density perturbation method.

1987 • 179 citations

Development and degeneration of retina in rds mutant mice: Photoreceptor abnormalities in the heterozygotes

1985 • 178 citations

Surfaces of rod photoreceptor disk membranes: integral membrane components.

1982 • 175 citations

Autosomal dominant retinitis pigmentosa: Four new mutations in rhodopsin, one of them in the retinal attachment site

1991 • 166 citations

Molecular cloning, primary structure, and orientation of the vertebrate photoreceptor cell protein peripherin in the rod outer segment disk membrane

1990 • 162 citations

Development and degeneration of retina inrds mutant mice: Electron microscopy

1984 • 161 citations

Topology of eukaryotic type II membrane proteins: Importance of N-terminal positively charged residues flanking the hydrophobic domain

1991 • 153 citations

Antigen-antibody interaction. Synthetic peptides define linear antigenic determinants recognized by monoclonal antibodies directed to the cytoplasmic carboxyl terminus of rhodopsin.

1988 • 149 citations

Identification of novel rhodopsin mutations associated with retinitis pigmentosa by GC-clamped denaturing gradient gel electrophoresis.

1991 • 140 citations

Role of the intradiscal domain in rhodopsin assembly and function.

1990 • 139 citations

The human retinal degeneration slow (RDS) gene: Chromosome assignment and structure of the mRNA

1991 • 139 citations

Degenerative retinal disorders: Clinical and laboratory investigations

1988 • 126 citations

Complete rescue of photoreceptor dysplasia and degeneration in transgenic retinal degeneration slow (rds) mice

1992 • 123 citations

Monoclonal antibodies to rhodopsin and other proteins of rod outer segments

1988 • 111 citations

Rhodopsin and autosomal dominant retinitis pigmentosa

1992 • 96 citations

Some cytological and initial biochemical observations on photoreceptors in retinas of rds mice.

1983 • 95 citations

On the molecular genetics of retinitis pigmentosa

1992 • 83 citations

Development and degeneration of retina in rds mutant mice: The electroretinogram

1984 • 65 citations

Differential distribution of opsin in the plasma membrane of frog photoreceptors: an immunocytochemical study.

1983 • 59 citations

Development and degeneration of retina in rds mutant mice: Light and electron microscopic observations in experimental chimaeras

1984 • 41 citations

Purification of retinol dehydrogenase from bovine retinal rod outer segments

1991 • 39 citations

Opsin gene expression during early and late phases of retinal degeneration in rds mice

1990 • 37 citations

Localization of the photoreceptor gene ROM1 to human chromosome 11 and mouse chromosome 19: sublocalization to human 11q13 between PGA and PYGM.

1992 • 36 citations

The Map Position of the rds Gene on the 17th Chromosome of the Mouse

1979 • 35 citations

Structural features of the terminal loop region of frog retinal rod outer segment disk membranes: II. Organization of the terminal loop complex

1987 • 34 citations

Nucleotide and predicted protien sequence of rat retinal degeneration slow (rds)

1990 • 31 citations

Development and degeneration of retina in rds mutant mice: observations in chimaeras of heterozygous mutant and normal genotype

1986 • 25 citations

Immunoassay of rod visual pigment (opsin) in the eyes of rds mutant mice lacking receptor outer segments

1985 • 24 citations

Molecular characterization of the retinal degeneration slow (rds) mutation in mouse.

1991 • 13 citations

Opsin localization and glycosylation in the developing BALB/c and rds mouse retina.

1987 • 3 citations