Growth inhibition of DU-145 prostate cancer cells by a Bcl-2 antisense oligonucleotide is enhanced by N-(2-hydroxyphenyl)all-trans retinamide

Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia

1988 • 2,380 citations

Cancer statistics, 1997

1997 • 2,045 citations

Molecular thanatopsis: a discourse on the BCL2 family and cell death

1996 • 1,412 citations

Somatic Frameshift Mutations in the BAX Gene in Colon Cancers of the Microsatellite Mutator Phenotype

1997 • 1,329 citations

Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity

1995 • 863 citations

The retinoid receptors.

1994 • 665 citations

Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers.

1996 • 596 citations

Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo.

1995 • 537 citations

Frequent detection of codon 877 mutation in the androgen receptor gene in advanced prostate cancers.

1994 • 364 citations

Control of programmed cell death in normal and leukemic cells: new implications for therapy

1993 • 297 citations

p53 oncogene mutations in three human prostate cancer cell lines

1993 • 296 citations

p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation.

1995 • 264 citations

Incidence of Prostate Cancer Diagnosis in the Eras Before and After Serum Prostate-Specific Antigen Testing

1995 • 232 citations

Elevated Levels of Apoptosis Regulator Proteins P53 and BCL-2 are Independent Prognostic Biomarkers in Surgically Treated Clinically Localized Prostate Cancer

1996 • 231 citations

Labelling DNA strand breaks with BrdUTP. Detection of apoptosis and cell proliferation

1995 • 211 citations

Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia

1988 • 210 citations

1,25-Dihydroxyvitamin D3 and 9-cis-Retinoic Acid Act Synergistically to Inhibit the Growth of LNCaP Prostate Cells and Cause Accumulation of Cells in G1*

1997 • 205 citations

Beta-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response.

1995 • 203 citations

Differential effects of N-(4-hydroxyphenyl)retinamide and retinoic acid on neuroblastoma cells: apoptosis versus differentiation.

1995 • 195 citations

Prevention of primary prostate cancer in Lobund-Wistar rats by N-(4-hydroxyphenyl)retinamide.

1991 • 178 citations

Effects of BCL-2 antisense oligodeoxynucleotides on in vitro proliferation and survival of normal marrow progenitors and leukemic cells

1994 • 162 citations

Treatment of prostate cancer in the rat with the synthetic retinoid fenretinide.

1993 • 155 citations

Androgens induce resistance to bcl-2-mediated apoptosis in LNCaP prostate cancer cells.

1995 • 154 citations

Apoptosis resistance increases with metastatic potential in cells of the human LNCaP prostate carcinoma line.

1996 • 152 citations

Induction of apoptosis in breast cancer cells in response to vitamin D and antiestrogens

1994 • 150 citations

Regulation of apoptosis induced by the retinoid N-(4-hydroxyphenyl) retinamide and effect of deregulated bcl-2

1995 • 146 citations

Induction of apoptosis by beta-lapachone in human prostate cancer cells.

1995 • 142 citations

bcl-2 overexpression combined with p53 protein accumulation correlates with hormone-refractory prostate cancer

1996 • 140 citations

Selective growth arrest and phenotypic reversion of prostate cancer cells in vitro by nontoxic pharmacological concentrations of phenylacetate.

1993 • 132 citations

Relative potency of testosterone and dihydrotestosterone in preventing atrophy and apoptosis in the prostate of the castrated rat.

1996 • 131 citations

Retinoid differentiation therapy in promyelocytic leukemia

1996 • 130 citations

Nerve Growth Factor Rescues Pigment Cells from Ultraviolet-Induced Apoptosis by Upregulating BCL-2 Levels

1996 • 124 citations

Inhibition of bcl-2 with antisense oligonucleotides induces apoptosis and increases the sensitivity of AML blasts to Ara-C.

1995 • 122 citations

Vitamin D and Prostate Cancer

1995 • 109 citations

Bcl-2 and p53 expression in node-negative breast carcinoma: A study with long-term follow-up

1996 • 109 citations

Down regulation of Bcl-2 is the first step on Fas-mediated apoptosis of male reproductive tract.

1996 • 104 citations

Suppression of squamous cell carcinoma growth and differentiation by retinoids.

1994 • 88 citations

Comparison of N-(4-hydroxyphenyl)retinamide and all-trans-retinoic acid in the regulation of retinoid receptor-mediated gene expression in human breast cancer cell lines.

1996 • 85 citations

Potentiation of retinoid-induced differentiation of HL-60 and U937 cell lines by cytokines

1991 • 65 citations

Differentiation of Cultured Human Melanoma Cells Induced by the Aromatic Fatty Acids Phenylacetate and Phenylbutyrate

1994 • 65 citations

Incidence of prostate cancer diagnosis in the eras before and after serum prostate-specific antigen testing

1995 • 63 citations

Paclitaxel (taxol) inhibits protein isoprenylation and induces apoptosis in PC-3 human prostate cancer cells.

1995 • 56 citations

Effects of retinoid X receptor-selective ligands on profileration of prostate cancer cells

1997 • 50 citations

Genetic Alterations in Prostate Cancer

1994 • 50 citations

p16 mutations/deletions are not frequent events in prostate cancer

1996 • 47 citations

Antisense oligodeoxyribonucleotide down-regulation of bcl-2 gene expression inhibits growth of the low-grade non-Hodgkin's lymphoma cell line WSU-FSCCL.

1995 • 45 citations

Effect of N-(4-hydroxyphenyl)retinamide on apoptosis in human breast cancer cells

1996 • 44 citations

Inhibition of breast and ovarian carcinoma cell growth by 1,25-dihydroxyvitamin D3 combined with retinoic acid or dexamethasone

1995 • 41 citations

The synthetic retinoid N-(4-hydroxyphenyl) retinamide (4-HPR) exerts antiproliferative and apoptosis-inducing effects in the androgen-independent human prostatic JCA-1 cells.

1995 • 31 citations

Growth Regulation and Cellular Changes during Differentiation of Human Prostatic Cancer LNCaP Cells as Induced by T Lymphocyte-Conditioned Medium

1995 • 31 citations

Retinoids in bladder, testis and prostate cancer: epidemiologic, pre-clinical and clinical observations.

1994 • 30 citations

New chemotherapeutic agents in acute myeloid leukemia.

1996 • 29 citations

Bcl-2 Oncoprotein Expression Is Increased Especially in the Portion of Small Cell Carcinoma within the Combined Type of Small Cell Lung Cancer

1996 • 24 citations

Differentiation Therapy

1992 • 23 citations

Regulation of apoptosis induced by the retinoid N-(4-hydroxyphenyl) retinamide and effect of deregulated bcl-2

1995 • 20 citations

Growth Attenuation in a Human Prostate Cell Line Mediated by a Phorbol Ester

1995 • 12 citations