The related FLT4, FLT1, and KDR receptor tyrosine kinases show distinct expression patterns in human fetal endothelial cells.

Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

1989 • 4,988 citations

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1992 • 4,631 citations

Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid

1983 • 3,942 citations

Angiogenic Factors

1987 • 3,702 citations

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo

1992 • 2,293 citations

Vascular Permeability Factor, an Endothelial Cell Mitogen Related to PDGF

1989 • 2,090 citations

The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor

1992 • 2,042 citations

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1993 • 1,961 citations

Regulatory Functions of the Vascular Endothelium

1990 • 1,899 citations

Molecular and Biological Properties of the Vascular Endothelial Growth Factor Family of Proteins

1992 • 1,612 citations

Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

1992 • 1,528 citations

Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation

1992 • 1,103 citations

Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor.

1991 • 999 citations

Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family.

1990 • 982 citations

Regulators of Angiogenesis

1991 • 959 citations

Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors.

1992 • 900 citations

Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing.

1992 • 880 citations

Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies

1988 • 667 citations

Two Classes of PDGF Receptor Eecognize Different Isoforms of PDGF

1988 • 603 citations

Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo

1987 • 578 citations

Isolation and characterization of a vascular endothelial cell mitogen produced by pituitary-derived folliculo stellate cells.

1989 • 568 citations

Identification of a new endothelial cell growth factor receptor tyrosine kinase

1991 • 529 citations

A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit.

1991 • 516 citations

Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types.

1988 • 514 citations

Synthesis of von Willebrand Factor by Cultured Human Endothelial Cells

1974 • 472 citations

Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms.

1993 • 467 citations

tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors.

1992 • 410 citations

Cell biology of endothelial cells

1987 • 356 citations

Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PlGF), are transcribed from a single gene of chromosome 14.

1993 • 317 citations

Postnatal growth and development of the lung.

1975 • 299 citations

A molecular analysis of mouse development from 8 to 10 dayspost coitumdetects changes only in embryonic globin expression

1987 • 298 citations

FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines.

1992 • 285 citations

Special Report The Complexity of Endothelial Cells: A Review

1989 • 233 citations

Purification of a glycoprotein vascular endothelial cell mitogen from a rat glioma-derived cell line.

1990 • 230 citations

Two molecules related to the VEGF receptor are expressed in early endothelial cells during avian embryonic development

1993 • 209 citations

The FLT4 gene encodes a transmembrane tyrosine kinase related to the vascular endothelial growth factor receptor.

1993 • 164 citations

Nucleotide sequence of pre-pro-von Willebrand factor cDNA

1986 • 152 citations

FLT4, a novel class III receptor tyrosine kinase in chromosome 5q33-qter.

1992 • 121 citations

Identification of a new endothelial cell growth factor receptor tyrosine kinase.

1991 • 101 citations

NYK/FLK-1: a putative receptor protein tyrosine kinase isolated from E10 embryonic neuroepithelium is expressed in endothelial cells of the developing embryo.

1993 • 90 citations

Human fetal extremity lengths in the interval from 9 to 21 menstrual weeks of pregnancy

1984 • 86 citations

Chromosomal localization of FLT4, a novel receptor-type tyrosine kinase gene

1992 • 82 citations

A radiation hybrid map of 18 growth factor, growth factor receptor, hormone receptor, or neurotransmitter receptor genes on the distal region of the long arm of chromosome 5

1992 • 81 citations

Developmental Aspects of the Human Lung

1973 • 36 citations

A novel endothelial tyrosine kinase cDNA homologous to platelet-derived growth factor receptor cDNA

1992 • 23 citations