BDNF, and full length and truncated TrkB expression in the hippocampus of the rat following kainic acid excitotoxic damage. Evidence of complex time-dependent and cell-specific responses

Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments

1995 • 2,090 citations

Physiology of the Neurotrophins

1996 • 1,908 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression

1990 • 1,238 citations

Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid-treated rats

1985 • 1,101 citations

Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain.

1990 • 993 citations

The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3

1991 • 940 citations

trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor

1991 • 830 citations

Functional Interactions of Neurotrophins and Neurotrophin Receptors

1995 • 825 citations

Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family

1990 • 817 citations

trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors.

1991 • 785 citations

The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain

1990 • 748 citations

Widespread patterns of neuronal damage following systemic or intracerebral injections of kainic acid: A histological study

1980 • 700 citations

Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain.

1990 • 700 citations

BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: Temporal patterns of induction distinct from NGF

1991 • 699 citations

Kainic acid induced limbic seizures: metabolic, behavioral, electroencephalographic and neuropathological correlates

1981 • 683 citations

Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death

1993 • 670 citations

Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline or pentetrazole: Metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy

1981 • 654 citations

Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors.

1995 • 612 citations

trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.

1989 • 604 citations

Neurotrophic factors and their receptors

1995 • 583 citations

Widespread Expression of BDNF But Not NT3 by Target Areas of Basal Forebrain Cholinergic Neurons

1990 • 529 citations

Kainic acid induced seizures: Neurochemical and histopathological changes

1983 • 526 citations

Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma.

1992 • 521 citations

Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system

1997 • 500 citations

Naturally Occurring Truncated trkB Receptors Have Dominant Inhibitory Effects on Brain-Derived Neurotrophic Factor Signaling

1996 • 472 citations

Immunocytochemical localization of TrkB in the central nervous system of the adult rat

1997 • 426 citations

NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults

1994 • 402 citations

Selective reinnervation of hippocampal area CA1 and the fascia dentata after destruction of CA3-CA4 afferents with kainic acid

1980 • 380 citations

Possible functional consequences of synaptic reorganization in the dentate gyrus of kainate-treated rats

1992 • 369 citations

Localization of brain-derived neurotrophic factor mRNA to neurons in the brain by in situ hybridization

1990 • 365 citations

Potentiated Necrosis of Cultured Cortical Neurons by Neurotrophins

1995 • 360 citations

Increased production of the TrkB protein tyrosine kinase receptor after brain insults

1993 • 344 citations

Chronic seizures and collateral sprouting of dentate mossy fibers after kainic acid treatment in rats

1988 • 341 citations

Hippocampal mossy fiber sprouting and synapse formation after status epilepticus in rats: Visualization after retrograde transport of biocytin

1995 • 339 citations

Neurotrophins: a family of proteins supporting the survival of neurons.

1994 • 290 citations

Synaptic Innervation Density Is Regulated by Neuron-Derived BDNF

1997 • 280 citations

Selective binding and internalisation by truncated receptors restrict the availability of BDNF during development

1995 • 270 citations

Calretinin is present in non-pyramidal cells of the rat hippocampus—I. A new type of neuron specifically associated with the mossy fibre system

1992 • 253 citations

Neuronal and nonneuronal expression of neurotrophins and their receptors in sensory and sympathetic ganglia suggest new intercellular trophic interactions

1995 • 247 citations

Coexpression of neurotrophins and their receptors in neurons of the central nervous system.

1993 • 242 citations

Regulation of brain-derived neurotrophic factor (BDNF) expression and release from hippocampal neurons is mediated by non-NMDA type glutamate receptors

1994 • 210 citations

Lesion‐induced mossy fibers to the molecular layer of the rat fascia dentata: Identification of postsynaptic granule cells by the Golgi‐EM technique

1983 • 193 citations

In Situ Hybridization of trkB and trkC Receptor mRNA in Rat Forebrain and Association with High‐affinity Binding of [¹²⁵I]BDNF, [¹²⁵I]NT‐4/5 and [¹²⁵I]NT‐3

1994 • 190 citations

Coordinated expression of messenger RNAs for nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 in the rat hippocampus following transient forebrain ischemia

1993 • 181 citations

Epilepsy induced collateral sprouting of hippocampal mossy fibers: Does it induce the development of ectopic synapses with granule cell dendrites?

1993 • 180 citations

Regionally specific and rapid increases in brain-derived neurotrophic factor messenger RNA in the adult rat brain following seizures induced by systemic administration of kainic acid

1992 • 174 citations

Expression of members of the trk family in the developing postnatal rat brain

1993 • 174 citations

Afferent and efferent synaptic conncetions sof somatostatin‐immunoreactive neurons in the rat fascia dentata

1990 • 174 citations

Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death

1993 • 164 citations

Truncated trkB Receptors on Nonneuronal Cells Inhibit BDNF-Induced Neurite Outgrowthin Vitro

1997 • 142 citations

COMPARATIVE STUDY OF BRAIN-DERIVED NEUROTROPHIC FACTOR MESSENGER RNA AND PROTEIN AT THE CELLULAR LEVEL SUGGESTS MULTIPLE ROLES IN HIPPOCAMPUS, STRIATUM AND CORTEX

1996 • 137 citations

Detection of Brain-derived Neurotrophic Factor in a Vesicular Fraction of Brain Synaptosomes

1997 • 128 citations

Truncated and Catalytic Isoforms of trkB are Co‐expressed in Neurons of Rat and Mouse CNS

1995 • 128 citations

Functional trkB neurotrophin receptors are intrinsic components of the adult brain postsynaptic density

1996 • 112 citations

Distribution of trkB tyrosine kinase immunoreactivity in the rat central nervous system

1993 • 104 citations

BDNF and trkB mRNA expression in the hippocampal formation of aging rats

1993 • 102 citations

Immunohistochemical Visualization of Brain‐derived Neurotrophic Factor in the Rat Brain

1995 • 98 citations

Change in Neurotrophins and Their Receptor mRNAs in the Rat Forebrain After Status Epilepticus Induced by Pilocarpine

1996 • 91 citations

BDNF Up‐Regulates TrkB Protein and Prevents the Death of CA1 Neurons Following Transient Forebrain Ischemia

1998 • 89 citations

Cellular hybridization for BDNF. trkB, and NGF mRNAs and BDNF-immunoreactivity in rat forebrain after pilocarpine-induced status epilepticus

1996 • 88 citations

Spatiotemporal selective effects on brain-derived neurotrophic factor andtrkB messenger RNA in rat hippocampus by electroconvulsive shock

1995 • 86 citations

Expression of NGF and NT3 mRNAs in Hippocampal Interneurons Innervated by the GABAergic Septohippocampal Pathway

1996 • 86 citations

Co-expression of mRNA for Neurotrophic Factors in Human Neurons and Glial Cells in Culture

1994 • 77 citations

Expression of GAP‐43 in the Granule Cells of Rat Hippocampus After Seizure‐induced Sprouting of Mossy Fibres: In Situ Hybridization and Immunocytochemical Studies

1994 • 70 citations

Regional Increases in Brain‐Derived Neurotrophic Factor and Nerve Growth Factor mRNAs During Amygdaloid Kindling, But Not in Acidic and Basic Fibroblast Growth Factor mRNAs

1996 • 62 citations

BDNF‐activated Sianal Transduction in Rat Cortical Glial Cells

1995 • 62 citations

Early induction of mRNA for calbindin-D28k and BDNF but not NT-3 in rat hippocampus after kainic acid treatment

1997 • 54 citations

Receptor‐mediated regulation of neuropeptide gene expression in astrocytes

1994 • 47 citations

Brain derived neurotrophic factor induces a rapid upregulation of synaptophysin and tau proteins via the neurotrophin receptor TrkB in rat cerebellar granule cells

1997 • 46 citations

Dopaminergic Transmitter Up-Regulation of Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) Synthesis in Mouse Astrocytes in Culture

1997 • 45 citations

Hippocampal mossy fiber sprouting is not impaired in brain-derived neurotrophic factor-deficient mice

1998 • 43 citations

Differential regulation of catalytic and non-catalytictrkB messenger RNAs in the rat hippocampus following seizures induced by systemic administration of kainate

1995 • 40 citations

The Calretinin‐containing Mossy Cells Survive Excitotoxic Insult in the Gerbil Dentate Gyrus. Comparison of Excitotoxicity‐induced Neuropathological Changes in the Gerbil and Rat

1996 • 33 citations

Induction of heat-shock protein-70 messenger RNA and protein following systemic kainate injection in the rat: Evidence of protein axonal transport

1995 • 11 citations

Chapter 18 Induction of non-catalytic TrkB neurotrophin receptors during lesion-induced synaptic rearrangement in the adult rat hippocampus

1995 • 3 citations