Expression and autoregulation of transforming growth factor β receptor mRNA in small-cell lung cancer cell lines

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Mechanism of activation of the TGF-β receptor

1994 • 2,298 citations

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.

1994 • 1,950 citations

TGFβ signals through a heteromeric protein kinase receptor complex

1992 • 1,519 citations

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

1992 • 1,071 citations

Betaglycan presents ligand to the TGFβ signaling receptor

1993 • 887 citations

Cloning of a TGF$beta; type I receptor that forms a heteromeric complex with the TGF$beta; type II receptor

1993 • 779 citations

Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system

1991 • 661 citations

Identification of human activin and TGFβ type I receptors that form heteromeric kinase complexes with type II receptors

1993 • 656 citations

Expression cloning and characterization of the TGF-β type III receptor

1991 • 638 citations

Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.

1988 • 604 citations

Characterization of Type I Receptors for Transforming Growth Factor-β and Activin

1994 • 558 citations

Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity.

1986 • 541 citations

Genetic changes in the transforming growth factor beta (TGF-beta) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-beta.

1994 • 431 citations

Cloning of a Type I TGF-β Receptor and Its Effect on TGF-β Binding to the Type II Receptor

1993 • 401 citations

Transforming growth factor-β inhibition of epithelial cell proliferation linked to the expression of a 53-kDa membrane receptor

1989 • 325 citations

TGF-β receptors and actions

1994 • 291 citations

Responsiveness to transforming growth factor-beta (TGF-beta) restored by genetic complementation between cells defective in TGF-beta receptors I and II

1991 • 252 citations

Transforming growth factor-β controls receptor levels for epidermal growth factor in NRK fibroblasts

1984 • 232 citations

Loss of receptors for transforming growth factor beta in human T-cell malignancies.

1994 • 219 citations

Growth inhibition by transforming growth factor beta (TGF-beta) type I is restored in TGF-beta-resistant hepatoma cells after expression of TGF-beta receptor type II cDNA.

1993 • 192 citations

Isolation and growth characteristics of continuous cell lines from small-cell carcinoma of the lung

1980 • 182 citations

The transforming growth factor beta receptors types I, II, and III form hetero-oligomeric complexes in the presence of ligand.

1993 • 181 citations

Inhibition of growth by transforming growth factor-beta following fusion of two nonresponsive human carcinoma cell lines. Implication of the type II receptor in growth inhibitory responses.

1992 • 176 citations

Characterization of three new variant type cell lines derived from small cell carcinoma of the lung

1986 • 147 citations

Transcriptional regulation of two serum-induced RNAs in mouse fibroblasts: equivalence of one species to B2 repetitive elements.

1985 • 120 citations

Molecular cloning and characterization of the human and porcine transforming growth factor-β type III receptors

1992 • 85 citations

TGF‐β regulation of epithelial cell proliferation

1992 • 84 citations

Characterization of three small cell lung cancer cell lines established from one patient during longitudinal follow-up.

1988 • 83 citations

Transforming growth factor β and cancer

1995 • 73 citations

Growth suppression by transforming growth factor β1 of human small-cell lung cancer cell lines is associated with expression of the type II receptor

1994 • 47 citations

Expression of transforming growth factor β (TGFβ) receptors and expression of TGFβ1, TGFβ2 and TGFβ3 in human small cell lung cancer cell lines

1993 • 46 citations

Transcriptional Regulation of Two Serum-Induced RNAs in Mouse Fibroblasts: Equivalence of One Species to B2 Repetitive Elements

1985 • 46 citations

COMPARISON OF CHARACTERISTICS OF HUMAN SMALL CELL CARCINOMA OF THE LUNG IN PATIENTS, IN VITRO AND TRANSPLANTED INTO NUDE MICE

1986 • 27 citations

Transforming Growth Factor .BETA.1 Selectively Increases Gene Expression of the Serine/Threonine Kinase Receptor 1 (SKR1) in Human Hepatoma Cell Lines.

1994 • 12 citations