Growth suppression by transforming growth factor β1 of human small-cell lung cancer cell lines is associated with expression of the type II receptor

Measurement of protein using bicinchoninic acid

1985 • 17,516 citations

A simple, rapid, and sensitive DNA assay procedure

1980 • 5,006 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

TGFβ signals through a heteromeric protein kinase receptor complex

1992 • 1,519 citations

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

1992 • 1,071 citations

Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells

1987 • 998 citations

Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation

1990 • 812 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system

1991 • 661 citations

Expression cloning and characterization of the TGF-β type III receptor

1991 • 638 citations

TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains

1990 • 612 citations

Cloning of a Type I TGF-β Receptor and Its Effect on TGF-β Binding to the Type II Receptor

1993 • 401 citations

A new type of transforming growth factor-beta, TGF-beta 3.

1988 • 396 citations

Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family.

1987 • 387 citations

Identification of another member of the transforming growth factor type beta gene family.

1988 • 326 citations

Transforming growth factor-β inhibition of epithelial cell proliferation linked to the expression of a 53-kDa membrane receptor

1989 • 325 citations

Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction.

1990 • 319 citations

Responsiveness to transforming growth factor-beta (TGF-beta) restored by genetic complementation between cells defective in TGF-beta receptors I and II

1991 • 252 citations

Transforming growth factor beta: potential autocrine growth inhibitor of estrogen receptor-negative human breast cancer cells.

1988 • 247 citations

Growth inhibition by transforming growth factor beta (TGF-beta) type I is restored in TGF-beta-resistant hepatoma cells after expression of TGF-beta receptor type II cDNA.

1993 • 192 citations

Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering.

1991 • 186 citations

Isolation and growth characteristics of continuous cell lines from small-cell carcinoma of the lung

1980 • 182 citations

TGF-beta 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector.

1992 • 182 citations

Inhibition of growth by transforming growth factor-beta following fusion of two nonresponsive human carcinoma cell lines. Implication of the type II receptor in growth inhibitory responses.

1992 • 176 citations

Differential effects of transforming growth factor β on human prostate cancer cells in vitro

1989 • 166 citations

Transforming growth factor beta 1 induces apoptotic cell death in cultured human gastric carcinoma cells.

1992 • 152 citations

Characterization of three new variant type cell lines derived from small cell carcinoma of the lung

1986 • 147 citations

TGF‐β receptors

1992 • 133 citations

Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene product.

1991 • 120 citations

Regulation of growth of normal ovarian epithelial cells andovarian cancer cell lines by transforming growth factor-ß

1992 • 113 citations

Structure and properties of the cellular receptor for transforming growth factor type beta

1986 • 104 citations

TGF‐β regulation of epithelial cell proliferation

1992 • 84 citations

Characterization of three small cell lung cancer cell lines established from one patient during longitudinal follow-up.

1988 • 83 citations

Expression of transforming growth factor β (TGFβ) receptors and expression of TGFβ1, TGFβ2 and TGFβ3 in human small cell lung cancer cell lines

1993 • 46 citations

Expression of transforming growth factor β1 by human endometrial carcinoma cell lines : inverse correlation with effects on growth rate and morphology

1990 • 40 citations

Subcellular localization of the retinoblastoma protein.

1991 • 39 citations

Alteration in growth, cell morphology, and cytoskeletal structures of KB cells induced by epidermal growth factor and transforming growth factor-β

1988 • 37 citations

Abnormalities in structure and expression of the retinoblastoma gene in small cell lung cancer cell lines and xenografts in nude mice.

1990 • 37 citations

Inactivation of the retinoblastoma gene does not lead to loss of TGF-beta receptors or response to TGF-beta in breast cancer cell lines.

1991 • 29 citations

COMPARISON OF CHARACTERISTICS OF HUMAN SMALL CELL CARCINOMA OF THE LUNG IN PATIENTS, IN VITRO AND TRANSPLANTED INTO NUDE MICE

1986 • 27 citations

Human small‐cell lung‐cancer cells are cytokine‐resistant but NK/LAK‐sensitive

1991 • 22 citations

Expression of transforming growth factor beta 1 by human endometrial carcinoma cell lines: inverse correlation with effects on growth rate and morphology.

1990 • 9 citations

Comparison of characteristics of human small cell carcinoma of the lung in patients, in vitro and transplanted into nude mice

1987 • 7 citations

Human small-cell lung-cancer cells are cytokine-resistant but NK/LAK-sensitive

1991 • 3 citations