TGF‐β regulation of epithelial cell proliferation

Tumor Suppressor Genes

1991 • 1,784 citations

The E2F transcription factor is a cellular target for the RB protein

1991 • 1,461 citations

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

1989 • 931 citations

TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop

1990 • 756 citations

Cellular targets for transformation by the adenovirus E1A proteins

1989 • 747 citations

TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains

1990 • 612 citations

Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor-growth inhibitor in serum-free medium.

1986 • 559 citations

Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity.

1986 • 541 citations

Transforming growth factor beta 1-induced changes in cell migration, proliferation, and angiogenesis in the chicken chorioallantoic membrane.

1990 • 470 citations

TGF-β1 inhibition of transin/stromelysin gene expression is mediated through a fos binding sequence

1990 • 444 citations

Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat.

1988 • 424 citations

Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation.

1990 • 397 citations

Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor beta.

1988 • 324 citations

Growth modulation of mouse keratinocytes by transforming growth factors.

1988 • 242 citations

Transforming growth factor-beta inhibits the generation of cytotoxic T cells in virus-infected mice.

1989 • 164 citations

Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene product.

1991 • 120 citations

Inhibition of early murine hemopoietic progenitor cell proliferation after in vivo locoregional administration of transforming growth factor-beta 1.

1989 • 107 citations

Transforming growth factor beta 1 regulation of c-myc expression, pRB phosphorylation, and cell cycle progression in keratinocytes.

1992 • 81 citations

Growth factors — from genes to clinical application

1990 • 76 citations

c-myc and pRB: Role in TGF- 1 Inhibition of Keratinocyte Proliferation

1991 • 25 citations