PKC-dependent Activation of Sphingosine Kinase 1 and Translocation to the Plasma Membrane

Functions of Ceramide in Coordinating Cellular Responses to Stress

1996 • 1,620 citations

Vascular Endothelial Cell Adherens Junction Assembly and Morphogenesis Induced by Sphingosine-1-Phosphate

1999 • 999 citations

Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

1993 • 879 citations

Sphingosine 1-phosphate signalling in mammalian cells

2000 • 698 citations

Sphingosine Kinase Expression Increases Intracellular Sphingosine-1-Phosphate and Promotes Cell Growth and Survival

1999 • 516 citations

Sphingosine 1-phosphate signalling in mammalian cells

2000 • 458 citations

Role of the Sphingosine-1-Phosphate Receptor EDG-1 in PDGF-Induced Cell Motility

2001 • 421 citations

Tumor necrosis factor-α induces adhesion molecule expression through the sphingosine kinase pathway

1998 • 404 citations

Sphingosine Kinase Interacts with TRAF2 and Dissects Tumor Necrosis Factor-α Signaling

2002 • 291 citations

Extracellular Export of Sphingosine Kinase-1 Enzyme

2002 • 281 citations

Involvement of Sphingosine 1-Phosphate in Nerve Growth Factor-Mediated Neuronal Survival and Differentiation

1997 • 278 citations

Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway.

1994 • 273 citations

Activation of Sphingosine Kinase by Tumor Necrosis Factor-α Inhibits Apoptosis in Human Endothelial Cells

1999 • 270 citations

Differential Regulation of Sphingomyelinase and Ceramidase Activities by Growth Factors and Cytokines

1995 • 222 citations

Purification and Characterization of Rat Kidney Sphingosine Kinase

1998 • 221 citations

Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptors

1998 • 208 citations

Sphingosine‐1‐Phosphate in Cell Growth and Cell Death^a

1998 • 202 citations

Expression of a Catalytically Inactive Sphingosine Kinase Mutant Blocks Agonist-induced Sphingosine Kinase Activation

2000 • 186 citations

EDG‐1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration

2001 • 167 citations

Dichotomy of Ca2+ Signals Triggered by Different Phospholipid Pathways in Antigen Stimulation of Human Mast Cells

2002 • 164 citations

Role of Sphingosine 1-Phosphate in the Mitogenesis Induced by Oxidized Low Density Lipoprotein in Smooth Muscle Cells via Activation of Sphingomyelinase, Ceramidase, and Sphingosine Kinase

1999 • 157 citations

Bimodal Regulation of Ceramidase by Interleukin-1β

1997 • 152 citations

Metabolism and selected functions of sphingolipids in the yeast Saccharomyces cerevisiae

1999 • 147 citations

Cystic Fibrosis Transmembrane Regulator Regulates Uptake of Sphingoid Base Phosphates and Lysophosphatidic Acid

2001 • 142 citations

Sphingosine 1-phosphate receptors

2001 • 139 citations

Activation of sphingosine kinase in pheochromocytoma PC12 neuronal cells in response to trophic factors

1997 • 99 citations

Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity

1996 • 78 citations

Ceramide and the eukaryotic stress response

1997 • 65 citations

Tumor Necrosis Factor-α Induces Stress Fiber Formation through Ceramide Production: Role of Sphingosine Kinase

2001 • 64 citations

Sphingosine 1-phosphate receptors.

2001 • 54 citations

TNFα‐induced glutathione depletion lies downstream of cPLA₂ in L929 cells

2001 • 24 citations