Brachyury and the T-box genes

Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction

1991 • 980 citations

Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

1997 • 909 citations

Expression pattern of the mouse T gene and its role in mesoderm formation

1990 • 854 citations

Cloning of the T gene required in mesoderm formation in the mouse

1990 • 847 citations

Expression of the T-box family genes,Tbx1-Tbx5, during early mouse development

1996 • 654 citations

The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo

1992 • 648 citations

no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene

1994 • 628 citations

Induction of muscle pioneers and floor plate is distinguished by the zebrafish no tail mutation

1993 • 502 citations

Characterization of a notochord-specific enhancer from the Brachyury promoter region of the ascidian, Ciona intestinalis

1997 • 455 citations

T-Brain-1: A homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex

1995 • 415 citations

The Brachyury gene encodes a novel DNA binding protein.

1993 • 406 citations

Expression pattern of the Brachyury gene in whole-mount T WIS/T WIS mutant embryos

1991 • 350 citations

eFGF regulates Xbra expression during Xenopus gastrulation.

1994 • 340 citations

Xenopus VegT RNA is localized to the vegetal cortex during oogenesis and encodes a novel T-box transcription factor involved in mesodermal patterning

1996 • 309 citations

The Brachyury gene encodes a novel DNA binding protein.

1993 • 308 citations

Development of the short‐tailed mutant in the house mouse

1935 • 305 citations

Mesodermal Control of Neural Cell Identity: Floor Plate Induction by the Notochord

1990 • 300 citations

The T protein encoded by Brachyury is a tissue-specific transcription factor.

1995 • 287 citations

Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm

1996 • 280 citations

Mesoderm formation in response to Brachyury requires FGF signalling

1995 • 276 citations

Evidence of a role for T-☐ genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity

1996 • 271 citations

Tbx6,a Mouse T-Box Gene Implicated in Paraxial Mesoderm Formation at Gastrulation

1996 • 256 citations

Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation

1996 • 241 citations

Inducing factors in Xenopus early embryos

1994 • 234 citations

Mutations affecting the formation of the notochord in the zebrafish, Danio rerio

1996 • 232 citations

Ectopic mesoderm formation in Xenopus embryos caused by widespread expression of a Brachyury homologue

1992 • 228 citations

An ancient family of embryonically expressed mouse genes sharing a conserved protein motif with the T locus

1994 • 225 citations

Immunohistochemical Analysis of the Brachyury Protein in Wild-Type and Mutant Mouse Embryos

1994 • 218 citations

The T gene is necessary for normal mesodermal morphogenetic cell movements during gastrulation

1995 • 212 citations

Expression cloning of a Xenopus T-related gene (Xombi) involved in mesodermal patterning and blastopore lip formation

1996 • 206 citations

Homologs of the mouse Brachyury gene are involved in the specification of posterior terminal structures in Drosophila, Tribolium, and Locusta.

1994 • 206 citations

The Xenopus T-box gene, Antipodean, encodes a vegetally localised maternal mRNA and can trigger mesoderm formation

1996 • 203 citations

A vegetally localized T-box transcription factor in Xenopus eggs specifies mesoderm and endoderm and is essential for embryonic mesoderm formation

1997 • 197 citations

Mutations affecting development of the notochord in zebrafish

1996 • 194 citations

Evolution of Mouse T-box Genes by Tandem Duplication and Cluster Dispersion

1996 • 189 citations

Conservation of Brachyury (T) genes in amphioxus and vertebrates: developmental and evolutionary implications

1995 • 183 citations

Brachyury - a gene affecting mouse gastrulation and early organogenesis

1992 • 180 citations

Gastrulation movements provide an early marker of mesoderm induction in Xenopus laevis

1987 • 172 citations

The Chick Brachyury Gene: Developmental Expression Pattern and Response to Axial Induction by Localized Activin

1995 • 166 citations

An Ascidian Homolog of the Mouse Brachyury (T) Gene is Expressed Exclusively in Notochord Cells at the Fate Restricted Stage

1994 • 160 citations

The Development of Normal and Homozygous Brachy (T/T) Mouse Embryos in the Extraembryonic Coelom of the Chick

1944 • 134 citations

Analysis of competence and of Brachyury autoinduction by use of hormoneinducible Xbra

1997 • 121 citations

Two novel chick T-box genes related to mouse Brachyury are expressed in different, non-overlapping mesodermal domains during gastrulation

1997 • 117 citations

Mesodern-inducing factors and mesodermal patterning

1995 • 113 citations

Patterning of the mesoderm in Xenopus: dose-dependent and synergistic effects of Brachyury and Pintallavis

1995 • 105 citations

THE DEVELOPMENT OF TWO TAILLESS MUTANTS IN THE HOUSE MOUSE

1938 • 104 citations

A homology domain shared between Drosophila optomotor-blind and mouse Brachyury is involved in DNA binding

1992 • 101 citations

Genetical studies on the skeleton of the mouse. XXIII. The development of brachyury and anury.

1958 • 100 citations

Specification of mesodermal pattern in Xenopus laevis by interactions between Brachyury, noggin and Xwnt-8.

1994 • 97 citations

Expression of T Protein in the Primitive Streak Is Necessary and Sufficient for Posterior Mesoderm Movement and Somite Differentiation

1997 • 87 citations

The human homolog T of the mouse T(Brachyury) gene; gene structure, cDNA sequence, and assignment to chromosome 6q27.

1996 • 84 citations

eFGF is expressed in the dorsal midline of Xenopus laevis.

1995 • 81 citations

Distinct regulatory control of the Brachyury gene in axial and non-axial mesoderm suggests separation of mesoderm lineages early in mouse gastrulation

1996 • 80 citations

Conservation of the T-box gene family from Mus musculus to Caenorhabditis elegans

1995 • 65 citations

The mouse Brachyury (T) gene

1995 • 45 citations

T-box family reunion

1997 • 44 citations

Tales of tails: Brachyury and the T-box genes

1997 • 41 citations

Dorso-ventral patterning in the neural tube

1993 • 35 citations

The mouse Brachyury gene and mesoderm formation

1990 • 29 citations

Does the T gene determine the anteroposterior axis of a mouse embryo?

1990 • 25 citations

TPromoter Activity in the Absence of Functional T Protein during Axis Formation and Elongation in the Mouse

1997 • 24 citations

The Brachyury protein: A T-domain transcription factor

1995 • 23 citations

The role of T genes in the organization of the notochord during chordate evolution

1995 • 17 citations

Is There aBrachyury the Second?Analysis of a Transgenic Mutation Involved in Notochord Maintenance in Mice

1995 • 17 citations

Xenopus Brachyury

1995 • 11 citations

The T-related gene (Trg), a Brachyury homologue in insects

1995 • 8 citations