TPromoter Activity in the Absence of Functional T Protein during Axis Formation and Elongation in the Mouse

Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides

1988 • 1,848 citations

The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo

1995 • 1,175 citations

A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes

1993 • 1,166 citations

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

1991 • 1,103 citations

Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction

1991 • 980 citations

A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo

1990 • 924 citations

Expression pattern of the mouse T gene and its role in mesoderm formation

1990 • 854 citations

Cloning of the T gene required in mesoderm formation in the mouse

1990 • 847 citations

fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation.

1994 • 784 citations

New type of POU domain in germ line-specific protein Oct-4

1990 • 753 citations

Murine FGFR-1 is required for early postimplantation growth and axial organization.

1994 • 748 citations

Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3.

1995 • 744 citations

Requirement of FGF-4 for Postimplantation Mouse Development

1995 • 743 citations

Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse

1992 • 676 citations

The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo

1992 • 648 citations

no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene

1994 • 628 citations

A dual receptor system is required for basic fibroblast growth factor activity

1991 • 589 citations

Induction of muscle pioneers and floor plate is distinguished by the zebrafish no tail mutation

1993 • 502 citations

Mice homozygous for a targeted disruption of the proto-oncogeneint-2have developmental defects in the tail and inner ear

1993 • 446 citations

Induction of a second neural axis by the mouse node

1994 • 420 citations

The Brachyury gene encodes a novel DNA binding protein.

1993 • 406 citations

A community effect in animal development

1988 • 388 citations

Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse.

1988 • 384 citations

Expression pattern of the Brachyury gene in whole-mount T WIS/T WIS mutant embryos

1991 • 350 citations

eFGF regulates Xbra expression during Xenopus gastrulation.

1994 • 340 citations

Activin signalling and response to a morphogen gradient

1994 • 328 citations

Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression.

1994 • 319 citations

FGF signalling in the early specification of mesoderm in Xenopus

1993 • 319 citations

The Brachyury gene encodes a novel DNA binding protein.

1993 • 308 citations

Development of the short‐tailed mutant in the house mouse

1935 • 305 citations

The T protein encoded by Brachyury is a tissue-specific transcription factor.

1995 • 287 citations

Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression.

1991 • 286 citations

Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm

1996 • 280 citations

Mesoderm formation in response to Brachyury requires FGF signalling

1995 • 276 citations

A truncated form of fibroblast growth factor receptor 1 inhibits signal transduction by multiple types of fibroblast growth factor receptor.

1992 • 272 citations

Ectopic mesoderm formation in Xenopus embryos caused by widespread expression of a Brachyury homologue

1992 • 228 citations

Mesoderm induction in Xenopus caused by activation of MAP kinase

1995 • 223 citations

Analysis of FGF function in normal and no tail zebrafish embryos reveals separate mechanisms for formation of the trunk and the tail

1995 • 221 citations

Immunohistochemical Analysis of the Brachyury Protein in Wild-Type and Mutant Mouse Embryos

1994 • 218 citations

The T gene is necessary for normal mesodermal morphogenetic cell movements during gastrulation

1995 • 212 citations

Whole-mount in situ hybridization in the mouse embryo: gene expression in three dimensions

1993 • 212 citations

Raf-1 kinase is essential for early Xenopus development and mediates the induction of mesoderm by FGF

1993 • 199 citations

Community effects and related phenomena in development

1993 • 199 citations

mRNA localization studies suggest that murine FGF-5 plays a role in gastrulation

1991 • 189 citations

Cell fate and morphogenetic movement in the late mouse primitive streak

1996 • 185 citations

The Chick Brachyury Gene: Developmental Expression Pattern and Response to Axial Induction by Localized Activin

1995 • 166 citations

Mesoderm-inducing properties of INT-2 and kFGF: two oncogene-encoded growth factors related to FGF

1989 • 154 citations

Cell fate in the shoot apical meristem of Arabidopsis thaliana

1992 • 154 citations

Assignment of genes to regions of mouse chromosomes.

1978 • 144 citations

In situ hybridisation.

1990 • 129 citations

Saturation germ line mutagenesis of the murine t region including a lethal allele at the quaking locus.

1988 • 121 citations

Chimeric analysis of T (Brachyury) gene function

1993 • 118 citations

A cell autonomous function of Brachyury in T/T embryonic stem cell chimaeras

1991 • 117 citations

Genetical studies on the skeleton of the mouse. XXIII. The development of brachyury and anury.

1958 • 100 citations

Distinct regulatory control of the Brachyury gene in axial and non-axial mesoderm suggests separation of mesoderm lineages early in mouse gastrulation

1996 • 80 citations

Murine FGF-4 gene expression is spatially restricted within embryonic skeletal muscle and other tissues

1993 • 53 citations

The mouse Brachyury (T) gene

1995 • 45 citations

Effects of the TWis mutation on notochord formation and mesodermal patterning

1995 • 36 citations

GPI expression in female germ cells of the mouse

1981 • 35 citations

Viability and metabolic activity of homozygous Brachyury (T) embryos

1977 • 8 citations