Mesodern-inducing factors and mesodermal patterning

The origin of pattern and polarity in the Drosophila embryo

1992 • 1,367 citations

Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes

1994 • 1,114 citations

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

1991 • 1,103 citations

Induction of epidermis and inhibition of neural fate by Bmp-4

1995 • 782 citations

A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse

1994 • 769 citations

A maternal mRNA localized to the vegetal hemisphere in xenopus eggs codes for a growth factor related to TGF-β

1987 • 747 citations

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

1995 • 731 citations

Nodal is a novel TGF-β-like gene expressed in the mouse node during gastrulation

1993 • 606 citations

Functional analysis of activins during mammalian development

1995 • 579 citations

Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development

1992 • 573 citations

A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos

1992 • 538 citations

Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate

1990 • 508 citations

DVR-4 (Bone Morphogenetic Protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction

1992 • 488 citations

Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

1992 • 486 citations

Identification and cloning of localized maternal RNAs from xenopus eggs

1985 • 464 citations

Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo

1994 • 463 citations

A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo.

1994 • 449 citations

A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin

1995 • 436 citations

Processed Vg1 protein is an axial mesoderm inducer in xenopus

1993 • 417 citations

Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation

1995 • 415 citations

On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo.

1994 • 396 citations

Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm

1993 • 365 citations

eFGF regulates Xbra expression during Xenopus gastrulation.

1994 • 340 citations

A nodal-related gene defines a physical and functional domain within the Spemann organizer

1995 • 332 citations

Activin signalling and response to a morphogen gradient

1994 • 328 citations

FGF signalling in the early specification of mesoderm in Xenopus

1993 • 319 citations

Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene.

1994 • 307 citations

Regional specification within the mesoderm of early embryos of Xenopus laevis

1987 • 286 citations

A mesoderm-inducing factor is produced by a Xenopus cell line

1987 • 276 citations

Mesoderm formation in response to Brachyury requires FGF signalling

1995 • 276 citations

Mesodermal patterning by an inducer gradient depends on secondary cell–cell communication

1994 • 267 citations

Dorsalization and neural induction: properties of the organizer in Xenopus laevis.

1983 • 267 citations

Localized BMP-4 Mediates Dorsal/Ventral Patterning in the Early Xenopus Embryo

1995 • 229 citations

Mesoderm induction by activin requires FGF-mediated intracellular signals

1994 • 225 citations

The biological effects of XTC-MIF: quantitative comparison with Xenopus bFGF

1990 • 220 citations

Activin-mediated mesoderm induction requires FGF

1994 • 208 citations

Secretion and mesoderm-inducing activity of the TGF-beta-related domain of Xenopus Vg1.

1993 • 177 citations

The frog prince-ss: a molecular formula for dorsoventral patterning in Xenopus.

1993 • 167 citations

A truncated bone morphogenetic protein 4 receptor alters the fate of ventral mesoderm to dorsal mesoderm: roles of animal pole tissue in the development of ventral mesoderm.

1994 • 162 citations

Direct and continuous assessment by cells of their position in a morphogen gradient

1995 • 150 citations

Induction of dorsal mesoderm by soluble, mature Vg1 protein

1995 • 150 citations

A novel retrovirally induced embryonic lethal mutation in the mouse: assessment of the developmental fate of embryonic stem cells homozygous for the 413.d proviral integration

1991 • 147 citations

Molecular Cloning and Functional Analysis of a New Activin β Subunit: A Dorsal Mesoderm-Inducing Activity in Xenopus

1995 • 147 citations

Effects of truncated activin and FGF receptors and of follistatin on the inducing activities of BVg1 and activin: does activin play a role in mesoderm induction?

1994 • 145 citations

An interaction between dorsal and ventral regions of the marginal zone in early amphibian embryos

1980 • 142 citations

Localized synthesis of the Vg1 protein during early Xenopus development

1989 • 129 citations

A role for cytoplasmic determinants in mesoderm patterning: cell-autonomous activation of the goosecoid and Xwnt-8 genes along the dorsoventral axis of early Xenopus embryos

1994 • 121 citations

FGF is a prospective competence factor for early activin-type signals in Xenopus mesoderm induction

1995 • 120 citations

Mesoderm-inducing factors in early vertebrate development.

1993 • 120 citations

Mesoderm induction and the control of gastrulation in Xenopus laevis: the roles of fibronectin and integrins

1990 • 116 citations

Expression of Activin mRNA during Early Development in Xenopus laevis

1993 • 101 citations

Developmental expression of the protein product of Vg1, a localized maternal mRNA in the frog Xenopus laevis.

1989 • 95 citations

Slow emergence of a multithreshold response to activin requires cell-contact-dependent sharpening but not prepattern

1994 • 78 citations

Slow emergence of a multithreshold response to activin requires cell-contact-dependent sharpening but not prepattern

1994 • 72 citations

Spatial and temporal expression of basic fibroblast growth factor (FGF-2) mRNA and protein in early Xenopus development

1994 • 55 citations

Morphological differences in Xenopus embryonic mesodermal cells are specified as an early response to distinct threshold concentrations of activin

1994 • 52 citations

Identification of Activins A, AB, and B and Follistatin Proteins in Xenopus Embryos

1994 • 44 citations

Inductive Signals: Revolving vertebrates

1995 • 39 citations

Localization of Activin and Follistatin Proteins in the Xenopus Oocyte

1994 • 30 citations

Expression of Activin Transcripts in Follicle Cells and Oocytes of Xenopus laevis

1993 • 29 citations

Manganese Free Radicals in Cobalt-60 Gamma-irradiated Strawberries

1966 • 9 citations