Splicing of Two Internal and Four Carboxyl-terminal Alternative Exons in Nonmuscle Tropomyosin 5 Pre-mRNA Is Independently Regulated during Development

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

SR proteins and splicing control.

1996 • 668 citations

Regulation of Alternative Splicing in Vivo by Overexpression of Antagonistic Splicing Factors

1994 • 612 citations

Distinct Functions of SR Proteins in Alternative pre-mRNA Splicing

1993 • 407 citations

The molecular basis for tropomyosin isoform diversity

1991 • 350 citations

Functional properties of non-muscle tropomyosin isoforms

1994 • 244 citations

β-Actin Messenger RNA Localization and Protein Synthesis Augment Cell Motility

1997 • 235 citations

Differential modulation of actin-severing activity of gelsolin by multiple isoforms of cultured rat cell tropomyosin

1989 • 224 citations

Requirement for Drosophila cytoplasmic tropomyosin in oskar mRNA localization

1995 • 211 citations

Nonmuscle and Muscle Tropomyosin Isoforms Are Expressed from a Single Gene by Alternative RNA Splicing and Polyadenylation

1986 • 190 citations

Expression of transduced tropomyosin 1 cDNA suppresses neoplastic growth of cells transformed by the ras oncogene.

1993 • 175 citations

Alpha-tropomyosin gene organization. Alternative splicing of duplicated isotype-specific exons accounts for the production of smooth and striated muscle isoforms.

1987 • 174 citations

Differential localization of tropomyosin isoforms in cultured nonmuscle cells.

1988 • 132 citations

The SR splicing factors ASF/SF2 and SC35 have antagonistic effects on intronic enhancer-dependent splicing of the beta -tropomyosin alternative exon 6A

1997 • 124 citations

Developmental analysis of tropomyosin gene expression in embryonic stem cells and mouse embryos.

1993 • 124 citations

Three novel brain tropomyosin isoforms are expressed from the rat alpha-tropomyosin gene through the use of alternative promoters and alternative RNA processing.

1990 • 112 citations

The molecular composition of neuronal microfilaments is spatially and temporally regulated

1996 • 98 citations

In vitro splicing of mutually exclusive exons from the chicken beta-tropomyosin gene: role of the branch point location and very long pyrimidine stretch.

1990 • 97 citations

Mapping the Functional Domains within the Carboxyl Terminus of α-Tropomyosin Encoded by the Alternatively Spliced Ninth Exon

1996 • 93 citations

Regulation of microfilament organization and anchorage-independent growth by tropomyosin 1.

1995 • 89 citations

Tropomyosin Localization Reveals Distinct Populations of Microfilaments in Neurites and Growth Cones

1997 • 89 citations

Splicing of pre-mRNA: mechanism, regulation and role in development

1993 • 86 citations

Lack of Drosophila cytoskeletal tropomyosin affects head morphogenesis and the accumulation of oskar mRNA required for germ cell formation.

1996 • 80 citations

Specificity of dimer formation in tropomyosins: influence of alternatively spliced exons on homodimer and heterodimer assembly.

1995 • 76 citations

In vitro and in vivo characterization of four fibroblast tropomyosins produced in bacteria: TM-2, TM-3, TM-5a, and TM-5b are co-localized in interphase fibroblasts.

1992 • 73 citations

Four fibroblast tropomyosin isoforms are expressed from the rat alpha-tropomyosin gene via alternative RNA splicing and the use of two promoters

1991 • 73 citations

Differential control of tropomyosin mRNA levels during myogenesis suggests the existence of an isoform competition-autoregulatory compensation control mechanism

1990 • 73 citations

Organization of the hTMnm gene

1988 • 68 citations

Intracellular Localization of Tropomyosin mRNA and Protein Is Associated with Development of Neuronal Polarity

1995 • 64 citations

Human fibroblast tropomyosin isoforms: Characterization of cDNA clones and analysis of tropomyosin isoform expression in human tissues and in normal and transformed cells

1993 • 63 citations

Expression of Transfected Mutant β-actin Genes: Transitions Toward the Stable Tumorigenic State

1987 • 63 citations

Actin and tropomyosin isoforms in morphogenesis

1997 • 62 citations

Forced expression of chimeric human fibroblast tropomyosin mutants affects cytokinesis.

1995 • 61 citations

Human hTMα Gene: Expression in Muscle and Nonmuscle Tissue

1988 • 59 citations

Alternatively spliced exons of the β tropomyosin gene exhibit different affinities for F-actin and effects with nonmuscle caldesmon

1995 • 53 citations

Alternative Splicing of a Human α-Tropomyosin Muscle-Specific Exon: Identification of Determining Sequences

1992 • 47 citations

Differential regulation of tropomyosin isoform organization and gene expression in response to altered actin gene expression.

1993 • 46 citations

The mRNA and RNA-copy pseudogenes encoding TM30_nm, a human cytoskdetal tropomyosin

1986 • 46 citations

The Sequence of the Alternatively Spliced Sixth Exon of α-Tropomyosin Is Critical for Cooperative Actin Binding but Not for Interaction with Troponin

1997 • 45 citations

Isolation and characterization of cDNA clones encoding a low molecular weight nonmuscle tropomyosin isoform.

1987 • 43 citations

Low molecular weight rat fibroblast tropomyosin 5 (TM-5): cDNA cloning, actin-binding, localization, and coiled-coil interactions

1996 • 41 citations

cis-acting sequences involved in exon selection in the chicken beta-tropomyosin gene.

1992 • 36 citations

Identification of novel alternatively spliced isoforms of the tropomyosin-encoding gene, TMnm, in the rat cochlea

1994 • 33 citations

Choice of 3' cleavage/polyadenylation site in beta-tropomyosin RNA processing is differentiation-dependent in mouse BC3H1 muscle cells.

1992 • 21 citations

Splicing of two alternative exon pairs in beta-tropomyosin pre-mRNA is independently controlled during myogenesis.

1992 • 21 citations

Temporally Distinctive Changes of Alternative Splicing Patterns during Myogenic Differentiation of C2C12 Cells

1995 • 19 citations

Nucleotide sequence of cDNA for nonmuscle tropomyosin 5 of mouse fibroblast

1990 • 18 citations